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EuroMillions Breakthrough Mining — 3036 Sources, 25943 Leads Extracted — E8 Intelligence Research

Mined 3036 lottery+quantum breakthroughs. Extracted 25943 leads across 13 categories. 23643 high-value leads found. Categories: {"CORRIDOR": 2202, "FORMULA": 2035, "GEOMETRIC": 897, "FORWARD_ATTEMPT": 2337, "QUANTUM": 2552, "TIMING": 274, "CELESTIAL": 2121, "GEMATRIA": 2235, "CON...

National immunisation recommendations: why country-specific evidence and context matter

National Immunisation Technical Advisory Groups (NITAGs) are independent expert groups issuing recommendations on the introduction and use of licensed vaccines in national programmes. They consider both context-free evidence — safety, efficacy, effectiveness — and country-specifi...

Fundamental Constants from the Microscopic Spectrum

This paper develops the fundamental-constant sector of Grand Consistency Theory (GCT) by establishing a spectral connection between the microscopic Constraint Laplacian and measurable physical constants. Planck’s constant, Newton’s gravitational constant, the cosmological curvatu...

Early Surgery in Crohn’s Disease: Clinical and Evolutionary Profile

Background: Crohn’s disease (CD) is a chronic condition with increasing prevalence, where early management is crucial for improving long-term prognosis. This study aimed to assess the rate of early surgery, identify associated factors, and compare the outcomes of patients undergo...

Multiscale physicochemical evolution of mined coal links structure transport and reaction kinetics during thermochemical conversion

Global reliance on coal for energy generation and chemical production necessitates physics-based frameworks that move beyond empirical bulk characterization toward predictive and sustainable utilization strategies. Coal is a heterogeneous, reactive porous medium whose structure,...

EuroMillions Breakthrough Mining — 3028 Sources, 25855 Leads Extracted — E8 Intelligence Research

Mined 3028 lottery+quantum breakthroughs. Extracted 25855 leads across 13 categories. 23555 high-value leads found. Categories: {"CORRIDOR": 2194, "FORMULA": 2027, "GEOMETRIC": 897, "FORWARD_ATTEMPT": 2329, "QUANTUM": 2544, "TIMING": 274, "CELESTIAL": 2113, "GEMATRIA": 2227, "CON...

Synthesis and evaluation of antioxidant and antimicrobial activity of new spiropyrrolos

In this research we synthesized the Fe3O4/TiO2/MWCNTs magnetic nanocomposites using water extract of Spinacia oleracea leaves and the high performance of synthesized catalyst was confirmed by employing of it in the multicomponent reaction of reaction of isatoic anhydride, tert-bu...

FAK regulates leptin-induced angiogenesis and vasculogenic mimicry in breast cancer

Abstract Leptin, an adipokine primarily secreted by adipose tissue, has been implicated in tumor progression by regulating angiogenesis. Leptin also plays a key role in tumor vascularization by promoting vasculogenic mimicry (VM). During tumor progression, leptin activates severa...

From frameworks to futures: health adaptation pathways across the Shared Socioeconomic Pathways

Abstract Effectively managing the rising health risks of climate change requires consideration of plausible adaptation pathways under a range of scenarios of changes in greenhouse gas emissions and socioeconomic development to systematically explore the solution space for climate...

Awake Tracheal Intubation Practice and Clinical Decision-Making in Brief Airway Scenarios Among Anesthesiologists in Türkiye: A Cross-Sectional Survey

Objective: Awake tracheal intubation (ATI) is recommended for an anticipated difficult airway, yet its use remains limited. This study evaluated anesthesiologists’ ATI practices and scenario-based decision-making and identified factors associated with its use.Material and Methods...

Cross-scale Data-Driven Heat Flow Prediction in the Ordos Basin and Adjacent Areas: An XGBoost Model with SHAP Interpretability

Summary Terrestrial heat flow is a fundamental parameter characterizing the thermal regime of sedimentary basins, but sparse and unevenly distributed measurements limit regional heat flow mapping. This study integrated cross-scale geological and geophysical features to compare XG...

A multidimensionalMuscle quality index in severe bbesity: relationships with ageing, adiposity, and functional performance

Traditional anthropometric indicators such as body mass index (BMI) may inadequately capture functional muscular impairment in obesity. To investigate a multidimensional composite muscle quality index (MQI) integrating relative strength and lower-limb functional power in adults w...

CHITOSAN-BASED NANOCARRIERS FOR ANTI-ASTHMATIC DRUG DELIVERY: FORMULATION PRINCIPLES, BIOLOGICAL RATIONALE AND TRANSLATIONAL CHALLENGES

Asthma treatment depends on reliable drug delivery to control bronchoconstriction and chronic airway inflammation. Chitosan-based nanocarriers are being investigated because they combine biodegradability, modifiable cationic charge, mucoadhesion and the ability to form particles...

Latent Meta-Abstraction over Transformer Representations: A Two-System Architecture for Persistent Meta-Abstraction and Compute Leverage

This concept paper proposes a two-system architecture pairing a conventional transformer (Primary Model) with a separately parameterized Meta-Abstraction Model restricted operationally to activation-derived Primary representations and its own latent memory. A smaller or lower-cos...

Grid4Earth: An Open-Source Python Ecosystem for Geospatial Data Integration Using an Ellipsoidal HEALPix DGGS

Abstract. The rapid growth in Earth observation (EO) and Digital Twin Earth data volumes creates a need for global, reproducible, and cloudnative spatial representations. Conventional latitude–longitude grids and projected tiling systems remain useful, but they introduce projecti...

eBPF-based cybersecurity mechanisms: a systematic literature review

Abstract Extended Berkeley Packet Filter (eBPF) has emerged as a kernel-level programmable framework enabling dynamic security enforcement in modern operating systems. While eBPF’s potential for cybersecurity applications has attracted significant research attention, existing wor...

Reason for Using Frequency and Percentage to Analyze Categorical Data

Categorical data, consisting of distinct groups or non-numerical categories, forms a fundamental part of empirical research across social sciences, healthcare, and business analytics. Analyzing such data requires appropriate statistical summaries that accurately reflect central t...

From Mirror to Autonomy to Self-Reference: Protocol-Level Markers of Autopoiesis in a Human–AI Coupled System

This paper presents a theory-generating case study of a human–AI coupled system over a 12-day window (six active days), inducing an operationalizable criterion (Criterion O) for observable markers of autopoiesis and committing to prospective classification pending an independent...

MoS 2 /Graphene Floating‐Gate Transistor Toward Non‐Volatile Memory and High‐Precision Synaptic Operations

ABSTRACT Molybdenum disulfide () and graphene, as two significant members of the two‐dimensional family, have garnered considerable attention for enhanced non‐volatile memory (NVM) applications. Nonetheless, the synaptic behavior of the /graphene floating‐gate structures is yet t...

Real-world implementation and evaluation of a pharmacogenomic clinical decision support system for allopurinol and HLA-B*58:01

Abstract Background Allopurinol-induced severe cutaneous adverse reactions (SCARs), including Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN), are strongly associated with the HLA-B*58:01 allele. Despite guidelines recommending genotyping prior to initiation,...