Research works

EFFECT OF NATURAL POLYPHENOL EXTRACTS ON HIGH-FRUCTOSE-INDUCED METABOLIC DYSREGULATION

High-fructose consumption has been implicated in the development of metabolic disorders characterized by obesity, insulin resistance, dyslipidemia, oxidative stress, inflammation, and hepatic dysfunction. This study evaluated the protective effects of natural polyphenol extracts...

MANAGEMENT OF KARNINI YONIVYAPAD WITH APAMARGA KSHARA: A CONCEPTUAL AYURVEDIC REVIEW

Karnini Yonivyapad is one of the twenty Yonivyapad described in Ayurvedic classics, characterized by the development of a Karnika-like growth at the Garbhashaya-dwara-mukha (cervix). Clinically, it presents with symptoms such as excessive mucoid vaginal discharge, itching, pelvic...

CONCEPT OF BHASMA: FROM SHODHANA AND MARANA TO MODERN PHYSICOCHEMICAL CHARACTERIZATION

Background: Bhasma represents a distinctive category of Ayurvedic medicinal preparations produced through a series of pharmaceutical procedures designed to transform metals and minerals into therapeutically suitable forms. The classical processes of Shodhana, Bhavana, Marana and...

FORMULATION AND EVALUATION OF PERIWINKLE HAIR SERUM

Herbal hair serums are becoming an increasingly important area in cosmetic dermatology due to their bioactive components and low risk of side effects. This study details the formulation and assessment of a new hair serum that features Catharanthus roseus (Periwinkle) extract as i...

UNDERSTANDING SWEDANA PRINCIPLES WITH MODERN THERMODYNAMICS MECHANISM

Swedana Karma is one among the main Panchakarma procedure in Ayurveda that induces the production of sweat, reduces stiffness (Stamba), heaviness (Gaurava), and controls the coldness of the body.[1] Swedana karma is widely used as Purvakarma for most of the Panchakarma procedures...

AYURVEDIC APPROACH TO AVASCULAR NECROSIS - A CASE REPORT

Avascular necrosis (AVN) is the death of bone tissue resulting from an interrupted blood supply, progressing from an initial ischemic phase to a necrotic stage that frequently affects the femur, humerus, and knees, with 16000 new cases annually in India. While often asymptomatic...

PHYSICOCHEMICAL ANALYSIS OF SHANKHDRAV RASA AND ITS IN-VITRO CYTOTOXIC ACTIVITY ON HT – 29 HUMAN COLORECTAL ADENOCARCINOMA CELL LINE

Ayurveda emphasizes the maintenance of health through the balance of Dosha, Agni, and Dhatu, while Rasa Shastra and Bhaishajya Kalpana describe pharmaceutical techniques for preparing safe and effective medicines. Shankhadrav Rasa is a classical distillation-based formulation pos...

AN AYURVEDIC MANAGEMENT OF FISSURE IN ANO (PARIKARTIKA): A CASE REPORT

Introduction: Parikartika is ano-rectal disease having symptoms like burning sensation, may associated with swelling per anus and hematochezia .Its prevalence has been increasing due to sedentary lifestyle and increased in consumption of junk food. Patient Information: A 27 years...

ROLE OF HERBAL MEDICINES IN THE MANAGEMENT OF POLYCYSTIC OVARY SYNDROME (PCOS): A REVIEW

Polycystic Ovarian Syndrome (PCOS) is a complex endocrine disorder commonly affecting women of reproductive age. In India, nearly two out of every ten women are affected by PCOS. The condition is characterized by polycystic ovarian morphology, ovulatory dysfunction, and hyperandr...

APPLICATION OF BETHESDA SYSTEM IN CYTOLOGICAL EVALUATION AND CORRELATION TO HISTOPATHOLOGY OF SOLITARY THYROID NODULE

Background: Thyroid nodules are common, and while most are benign, solitary thyroid nodule (STN) carry a risk of malignancy. Fine-needle aspiration cytology (FNAC) remains the cornerstone for preoperative evaluation. The Bethesda System for Reporting Thyroid Cytopathology (BSRTC)...

GREEN-SYNTHESIZED ZINC OXIDE NANOPARTICLES FROM CYMBOPOGON CITRATUS EXHIBIT ENHANCED ANTIBACTERIAL AND ANTIBIOFILM ACTIVITY AGAINST MULTIDRUG-RESISTANT ESCHERICHIA COLI ISOLATED FROM RETAIL FISH

The increasing prevalence of multidrug-resistant (MDR) foodborne bacteria has created an urgent need for sustainable antimicrobial alternatives capable of overcoming conventional antibiotic resistance. The present study investigated the antibacterial and antibiofilm potential of...

FORMULATION AND PRELIMINARY EVALUATION OF CAFFEINE LOZENGES PREPARED USING A SILICON MOLD

Caffeine is a widely consumed beverage containing caffeine, which is known for its stimulating effects. The present work aimed to formulate Caffeine lozenges for oral delivery. The formulation was prepared using Caffeine along with suitable excipients such as sweetening agents, b...

CLIMATE CHANGE AND ITS IMPACT ON INDIA

Climate change is one of the main environmental challenges facing the world today. India is facing several problems. Climate change is associated with various adverse impacts on agriculture, water resources, forest and biodiversity, health, coastal management and increase in temp...

PHARMACOLOGICAL INVESTIGATION OF ANTI-INFLAMMATORY ACTIVITY OF COMBINED EXTRACT OF OPHIOPOGON JABURAN AND PANDANUS AMARYLLIFOLIUS USING EXPERIMENTAL ANIMAL MODEL

The present study aimed to develop and evaluate polyherbal suspension of Ophiopogon jaburan and Pandanus amaryllifolius extracts for antioxidant and anti-inflammatory activity. Methanolic extracts were prepared by Soxhlet extraction and evaluated for percentage yield, phytochemic...

FORMULATION AND EVALUATION OF PREBIOTIC BIOGEL FROM GARCINIA INDICA(RIND) FOR SKIN HEALTH

The present study focused on the formulation and evaluation of a prebiotic biogel containing Garcinia indica (kokum) rind extract for potential skin-care applications. Kokum rind was shade-dried, powdered, and extracted using 70% ethanol by maceration. The obtained extract was su...

COMPARATIVE ASSESSMENT OF EMOTIONAL DISTRESS AMONG SCHOOL GOING ADOLESCENT GIRLS USING DEPRESSION, ANXIETY AND STRESS 21 (DASS-21) AND HOSPITAL BASED ANXIETY AND DEPRESSION (HADS) SCALES

Background: Adolescent girls are particularly vulnerable to depression, anxiety, and stress because of rapid biological, psychological, and social changes. Screening for psychosocial-wellbeing and understanding the interrelationship between screening results is a matter of resear...

EFFECTIVENESS OF KUKKUTANDA SWEDA AND ALLIED AYURVEDIC INTERVENTIONS IN BELL'S PALSY: A CLINICAL CASE REPORT

Background: Facial expressions are the universal medium of emotion and communication. In Ardita these features are impaired due to Vāta vitiation, leading to facial distortion and paralysis. It closely correlates with Bell’s palsy, an acute lower motor neuron type of facial nerve...

VARANADI KASHYAM: AN HERBAL PRODUCT FOR PROSTATE TREATMENT

Varanadi Kashyam is an ayurvedic proprietary medication that commonly used for the treatment of urinary problems, including Benign Prostatic Hyperplasia (BPH) and reduces inflammation-induced urinary retention. Traditionally, it is used for the treatment of fatty liver disease, a...

A REVIEW OF LEPA KALPANA WITH SPECIAL REFERENCE TO MODERN HERBAL DUSTING POWDER

Lepa Kalpana is a well-established external pharmaceutical dosage form described in Ayurveda under Bahiparimarjana Chikitsa.[1] Among its various forms, Anulepana is advocated as a daily topical application for maintaining skin hygiene, enhancing complexion, controlling perspirat...

REVISITING THE VIDDHA KARMA IN AYURVEDIC TRADITION: A COMPREHENSIVE ANALYSIS

Vidha Karma is a unique parasurgical (Anushastra karam) procedure described in Ayurveda by Acharya Sushruta, among the 8 shastra karma, that involves therapeutic puncturing of specific anatomical sites to relieve pain (Shoolghana Chikitsa) and manage various diseases. Rooted in t...