Research works

Evaluating the toxicity of polystyrene micro- and nanoplastics in human bronchial epithelial cells: differences and challenges using aerosol and suspension exposures

Objective: Studies investigating toxicity of airborne micro- and nanoplastics (MNPs) are mostly based on conventional submerged cell cultures while limited studies utilize air-liquid interface (ALI) systems. Inherent differences in these culture/exposure modalities, such as parti...

Tuberculous Meningitis in Pediatric Patients: Diagnosis, Clinical Course, and Outcomes in the Modern Era

Tuberculous meningitis (TBM) is a critically severe form of extrapulmonary tuberculosis in pediatric patients. Presents a significant diagnostic challenge during the early stages of clinical manifestation. Delayed recognition of meningeal tuberculous inflammation leads to the inv...

Silica Nanoparticles Elicit Pulmonary Inflammation via STING-Dependent Activation of NF-κB p65 Signaling Pathway

Silica nanoparticles (SiNPs) are common nanoparticles that are widely used in industrial and medical applications. Inhalation exposure to SiNPs is frequently inevitable in modern society. While the adverse effects of SiNPs on lung injury have been extensively documented, the intr...

The Correlation of Psychological Symptoms, Quality of Life and Resilience in Patients with Recurrent Non-Melanoma Skin Cancer

Recurrent non-melanoma skin cancer (NMSC) may be accompanied by cosmetic, functional, and emotional consequences. Aims: To examine associations among psychological symptoms, quality of life, resilience, and religiosity and to compare psychological outcomes between patients treate...

Health-Related Quality of Life and Associated Factors in Long-Term Breast Cancer Survivors With and Without Lymphedema: A Cross-Sectional Study

Breast cancer-related lymphedema is a common long-term complication of breast cancer treatment that may continue to affect survivors well beyond active treatment. This study compared health-related quality of life between long-term breast cancer survivors with and without lymphed...

When safe havens fail: regime-dependent spillover connectedness among African stock markets, precious metals, and cryptocurrencies

Abstract This study examines the dynamic and quantile-dependent spillover connectedness among African stock markets, precious metals, and cryptocurrencies. Using daily data for seven major African stock markets, three precious metals, and three cryptocurrencies from July 2007 to...

Building Better Environments: A Baker’s Dozen of Methodologies for Configuring and Selecting Emulation Environments in EAASI

Abstract Emulation-as-a-Service Infrastructure (EAASI) is a digital preservation framework that enables users to configure and interact with emulated computing environments through a web browser. In the last decade, EAASI has been deployed in North America and Australia, demonstr...

Joint Inversion of Seismic and Geoelectrical Data Targeting Geological Faults

Near-surface geological faults play a crucial role in subsurface systems because they influence fluid flow and transport and can cause geotechnical failure. Topography can sometimes indicate the presence of fault zones, particularly in active tectonic settings where geomorphic fe...

From training to transformation: considering the importance of the post-training environment as a catalyst for sustained behaviour change

Purpose Research has extensively examined change management programmes, yet studies continuously report a failure rate of approximately 70%. One often cited factor is insufficient provision of ongoing training. Where included, training is often treated as a solitary event without...

Peer comparisons and the cost of pro-social behavior: Evidence from the lab

Behavioral nudges in the form of peer-comparison information have, in many cases, proven effective in promoting pro-social behavior. The most prominent example is the use of home energy reports in electricity markets. While there is evidence that peer comparisons can induce reduc...

Water-State Reorganization as the Molecular Origin of the Thermo-Mechanical Anomaly in Hydrated Polymer Networks

Abstract Hydrated polymer networks are widely used across diverse environmental conditions, including varying humidity and temperature ranges, for numerous applications. The three distinct types of water present within hydrated polymer networks, namely tightly bound water, loosel...

Prioritizing site groups for intrinsic biodiversity assets using complementarity and not just rarity

Abstract Conservation practitioners rightfully focus on at‐risk species when valuing biodiversity assets and prioritizing spatial units. However, sites often contain few if any of those species, making valuation and prioritization difficult. A complementarity approach that incorp...

Follow up immunogenicity of a mixed vaccination schedule with one dose of nonavalent and one dose of bivalent HPV vaccines 36 months post-vaccination among boys and girls

Background: Following up on previously published short-term findings, we assessed the persistence of the immune response at 36 months following mixed-HPV vaccination schedules using one nonavalent (9vHPV) dose and one bivalent (2vHPV) dose (administered interchangeably) compared...

Multi-stage single-cell atlas of a chordate non-embryonic development unveils dedifferentiating bud founder cells

Abstract Colonial tunicates are the only chordates capable of forming fully functional bodies from somatic tissues through non-embryonic development, or budding. In Botryllus schlosseri , budding produces new individuals (zooids) from a portion of the peribranchial epithelium of...

Diffusive Particles Travel Through a Tube in Less Time than the Flowing Fluid in Which They Are Suspended

This article presents a summary of recent theoretical investigations on the residence time distribution (RTD) of particles in laminar flow tubes based on the stochastic simulation of particles trajectories and on a formerly unpublished comparison of the numerical simulation resul...

CAF-1 in Replication and Repair: A Critical Genetic Mediator of Synthesis-Coupled Nucleosome Assembly

Eukaryotic genomes are organized into chromatin, a highly compact structure in which DNA is packaged into nucleosomes. Nucleosome formation, where DNA is wrapped around histone proteins, is essential for genome stability. This compaction protects DNA from damage and regulates acc...

The Radical-Graded Hochschild Cohomology of Truncated Cycle Algebras

Let \(Q_e\) be the oriented cycle on \(e\geq2\) vertices and let \(A=kQ_e/J^N\), where \(J\) is the arrow ideal and \(N>e\). Suppose that \(\operatorname{char}k\nmid N\), and put \(\mathfrak m=\operatorname{rad}\operatorname{HH}^0(A)\). The positive-degree Hochschild cohomology g...

Fable Is Gone — Don't Give Up: OpenRouter Fusion + Chinese LLMs + Review Layer (archived 2026-09-03)

How to set up opencode with OpenRouter Fusion and five Chinese LLMs (DeepSeek, Kimi, more), plus a GPT review layer — full opencode.json config included. Archived version of https://comcomponent.com/en/blog/2026/06/14/000-opencode-fusion-chinese-llms/, as published on 2026-09-03....

A Novel Task-Package Partitioning Method for Shipbuilding Considering Four-Dimensional Features of Intermediate Products

Shipbuilding task packages are commonly defined from professional experience, which can produce heterogeneous work content within packages, dense coordination interfaces across packages, and uneven labor-time allocation. This study formulates task-package partitioning as a multi-...

Immunohistochemical detection of high-risk human papillomavirus E6/E7 oncoproteins is associated with aggressive clinicopathological features in prostate cancer: a Sudanese cohort study

Abstract Background The role of human papillomavirus (HPV) in prostate cancer development remains uncertain, despite accumulating evidence of a potential link in certain populations. While HPV is a known cause of several epithelial cancers, its connection to prostate cancer (PCa)...