Research works

Moving From Laboratory to Clinical Metrics for Diagnostic Tests

This Viewpoint explores the distinction between analytical and diagnostic performance measures.

Desire, Ruin, and Ecological Resistance: Reading Sanduk Through Eco-socialism and Eco-feminism

This study examines Siddhartha Chanakya’s SandukFootnote1 (2025), an independent Indian film that transforms the imagery of war into a radical ecological allegory of life at the limits of the Anthropocene. Set in a post-nuclear wasteland stripped of history and national identity,...

Intrinsic capacity decline and multilevel intervention needs of disabled older adults in nursing homes: a qualitative study based on the social-ecological systems theory

Intrinsic capacity (IC) is a central pillar of healthy ageing. Diminished IC is closely associated with poorer health outcomes and a greater degree of care dependence among disabled older adults. This study used the social-ecological framework to examine lived experiences and int...

Rural–Urban Migration and Sustainable Integration in China: Institutional Barriers and Pathways toward Inclusive Urban Citizenship

Abstract China has experienced one of the largest internal migration processes in modern history, driven by rapid industrialization, economic restructuring, and urban expansion since the late 1970s. Rural-to-urban migration has significantly contributed to China’s economic transf...

Design and mechanistic study of hollow SiO 2 ‐based porous liquids for catalytic CO 2 cycloaddition

Abstract Porous liquids (PLs) are novel materials with permanent pores, showing promise for gas capture and catalysis. Hollow SiO 2 (HS) is commonly used to construct Type I PLs due to its well‐defined structure and functionalizable surface. Here, ionic liquids IL1–5 with catalyt...

Inter-Rater Agreement in PD-L1 (22C3) Expression Evaluation in Colon Cancer

Programmed death-ligand 1 (PD-L1) is a predictive biomarker in various cancers. In colorectal cancer, PD-L1 expression evaluation is not part of the routine examination and standardized evaluation methods are lacking. This study aimed to examine inter-rater agreement in PD-L1 exp...

Quantifying spatially explicit reductions in wheat irrigation demand across the Indus basin through laser land leveling

Farmers in the Indus River Basin often irrigate their crops using surface irrigation on uneven fields, resulting in reduced irrigation performance and high irrigation demand. Assessment of irrigation performance is essential for reducing irrigation water use and identifying viabl...

Ultra-fast battery health estimation from random 100 mV charging fragments using conditional generative diffusion

State-of-health (SOH) estimation is essential for lithium-ion battery management. However, real-world disruptions often result in fragmented battery data, making reliable SOH estimation challenging. Generative artificial intelligence offers a promising paradigm to address these l...

Committed Computation Traces: Hybrid Verification of Neural Network Inference Between Probabilistic Replay and Zero-Knowledge Proofs

Organizations increasingly outsource neural network inference to third-party compute providers, and have no mechanism to confirm that the computation they paid for is the computation that ran. A provider can substitute a cheaper or quantized model, skip layers, return cached resu...

E8‑Phi Resonant Topology for Adaptive Antenna Arrays — E8 Intelligence Research

By mapping the 240 E8 root vectors onto the 132 Hz harmonic using φ‑scaled phase increments, a self‑similar lattice emerges that defines a new resonant topology for directional antenna arrays. The lattice's discrete symmetry ensures constructive interference at integer multiples...

Pressure-Induced Transitions in the Friction and Wear of Self-Lubricating PEO-Graphite Coatings for Magnesium-Polymer Sliding

This study investigates the influence of nominal contact pressure on the tribological behaviour of oxide coatings produced by plasma electrolytic oxidation (PEO) on AZ31B magnesium alloy and subsequently modified with graphite. While the effects of composition are well documented...

THEORETICAL ARCHITECTURE, MACROECONOMIC SUSTAINABILITY, AND INSTITUTIONAL GOVERNANCE IN THE DIRECT PARTICIPATORY POLITICAL SYSTEM

ABSTRACT This manuscript establishes the structural, epistemological, and institutional foundations of the DIRECT PARTICIPATORY POLITICAL SYSTEM. It addresses current international debates regarding the systemic crisis of representative democracy, public administration failures,...

Effectiveness of Multidomain Cardiac Rehabilitation After Myocardial Infarction by Patient Frailty: Prespecified Subgroup Analysis of the PIpELINe Trial

BACKGROUND: Frailty is common among older patients surviving myocardial infarction, is associated with adverse outcomes, and is often perceived as a barrier to cardiac rehabilitation (CR). The aim of this study is to determine whether frailty influences prognosis after myocardial...

Marketing Strategies and Market Performance of Ayurvedic Products: Evidence from Seller and Consumer Perspectives in Karnataka

The rapid expansion of the Ayurvedic sector in India reflects a broader shift toward natural, preventive, and holistic healthcare systems. Karnataka has emerged as a key regional hub for Ayurvedic production and consumption due to its rich biodiversity, strong manufacturing base,...

Efficient nitrogen management as a win-win strategy for air quality, health, and climate

Reactive nitrogen (Nr) management links climate policy, air quality and food production, yet its combined impacts remain poorly quantified. Here, we conduct ensemble simulations with two global climate models, Goddard Institute for Space Studies (GISS) and Community Earth System...

HomocamptothecinPayloads with Enhanced Potency forAntibody-Drug Conjugates

Abstract Camptothecin derivatives, exemplified by DXd, are a dominant class of payloads for antibody-drug conjugates (ADCs). Herein, we describe the design and synthesis of H2, a novel homocamptothecin featuring a simplified hydroxybutyl structure that circumvents the complex ass...

Knowledge and Risk Perception Regarding Skin Cancer in Immunosuppressed Patients: A Systematic Review and Meta-Analysis

Immunosuppressed patients have a substantially increased risk for developing skin cancer. Therefore, it is mandatory that such patients are adequately informed and aware of skin cancer and their increased risk to modify their behavior. Numerous studies have evaluated the topic, b...

When Legal Grounds Expire: Warrant Withdrawal, Dependency Cascades, and Living Normative Memory in CriptoIUS

Legal artificial intelligence is commonly evaluated at the level of the answer, but consequential legal systems require a different object of governance: the continuing warrant for institutional reliance. A legal conclusion may have been well grounded when produced and yet become...

Sector Paper XXV — The δI Substrate and the Unified Recovery of All Physics

Sector Paper XXV delivers the full structural recovery of all major physics domains from the δI‑substrate, completing the emergence chain of UN Theory. Using only public‑safe correlation geometry, alignment‑mode structure, horizon dynamics, collapse‑energy operators, and ξ‑field...

Efficacy and evidence certainty of traditional Chinese exercises for musculoskeletal disorders: an umbrella review of meta-analyses

Objectives To comprehensively evaluate the efficacy and exercise prescription parameters of traditional Chinese exercises (TCEs) on health outcomes in patients with musculoskeletal disorders (MSDs) and rigorously assess the certainty of the evidence. Design Umbrella review. Data...