Research works
The research papers we track — the newest first. Works with a plain-language summary link to it.
140262 work(s)
- Health & MedicineOpen access
Metal artifact reduction sequence MRI in hip periprosthetic joint infection management
Aims: There is currently no validated noninvasive method to determine infection control prior to prosthesis reimplantation during the two-stage revision process for hip periprosthetic joint infections (PJI) after total hip arthroplasty (THA). This prospective study investigates w...
- Materials & Energy
Molecular Design for the Multidimensional Modulation of Supramolecular Nanoparticle Interactions
Abstract Surface ligand engineering based on reversible supramolecular hydrogen bonding provides a versatile strategy for programmable nanoparticle (NP) self-assembly, yet quantitatively linking the molecular structure to interparticle interactions remains challenging. Here, expl...
- Climate & EnvironmentOpen access
Research on climate effects of large herbivores in Europe: a systematic map
Abstract Background Land management practices have significant impacts on biodiversity and climate change processes. Conservation and rewilding practitioners are increasingly seeking to enhance ecosystem functions and carbon sequestration simultaneously, encouraged by climate pol...
- Health & MedicineOpen access
OBJECTIVES: Dental caries results from dysbiotic shifts in the microbial community, so modulating biofilm composition represents a valid preventive strategy. The aim of this double-blind randomized crossover in situ study was to investigate how a fluoride rinse can modify the com...
- AI & ComputingOpen access
SAC-Net: Structure-Aware Collaborative Network for Graph Similarity Computation
Abstract Graph Similarity Computation (GSC) is a core task in graph analysis. However, current mainstream GNN-based similarity models still suffer from two fundamental bottlenecks. First, constrained by the inherent mechanism of recursive local aggregation, namely the 1-Weisfeile...
- AI & ComputingOpen access
Triangle Sums, Peripheral Cycles, and Contractions for Orderable Cographic Matroids
For closed simplicial surface triangulations, this preprint proves a general triangle-rooted gluing theorem for compatible cographic orderings and an exact if-and-only-if criterion for triangle sums. It constructs infinite families of 3-connected regular non-graphic orderable cog...
- BiologyOpen access
Innate immunity provides a critical first line of defense against pathogens and homeostatic perturbations. Pattern recognition receptors detect these disruptions and initiate immune responses through multi-protein complex formation to drive inflammatory signaling and cell death p...
- Health & MedicineOpen access
BACKGROUND: Rural immersion programs are commonly used to expose medical students to rural practice using curriculum-embedded placements. However, evidence regarding short-term, funded, voluntary, rural immersion placements that are not part of standard curricula-based training a...
- Society & EconomicsOpen access
The Internet as Precedent: Architectural Lessons for Federated Computing
This technical note examines the Internet as an architectural precedent for Federated Computing. The analogy lies in preserving local autonomy by making only the conditions required across boundaries explicit. It is not a proposal for a Federated Computing protocol stack, nor a d...
- Physics & Space
Abstract The spin ladder model is an important platform bridging one-dimensional and two-dimensional magnetic systems, with its physical properties modulated by geometric configuration. As such, the S = 1/2 two-leg antiferromagnetic spin ladder has attracted attention due to its...
- Health & MedicineOpen access
MODERN METHODS OF TREATMENT OF PATIENTS WITH OBSTRUCTIVE JAUNDICE OF TUMOR ORIGIN
Objective: To evaluate the clinical significance of modern surgical and minimally invasive biliary decompression methods in patients with obstructive jaundice of tumor origin and to optimize treatment strategies. Materials and Methods: The treatment outcomes of 235 patients trea...
- Materials & EnergyOpen access
Abstract The variational quantum Eigensolver (VQE) provides a scalable route to molecular ground-state energies on near-term quantum hardware, but its accuracy degrades rapidly as system size grows because hardware-efficient ansätze cannot span the full correlation subspace. We...
- Health & MedicineOpen access
Abstract Background Radioactively labeled somatostatin analogs (SSAs) are used in PET imaging of meningiomas due to the high expression of somatostatin receptor (SSTR) subtype 2. 18 F-labeled SSTR-tracers offer several economic and logistical advantages over 68 Ga-labeled tracers...
- AI & ComputingOpen access
Imputing longitudinal PROM data at the item and score level in clinical trials
Abstract Background Missing data in patient-reported outcome measures (PROMs) can affect estimation accuracy and inferential validity, particularly under missing-at-random (MAR) mechanisms. Multiple imputation (MI) is commonly recommended, but the relative performance of item-lev...
- Health & MedicineOpen access
Abstract Background Intraoperative hypotension is a common occurrence during general anaesthesia that has consistently been associated with perioperative organ injury. While international consensus guidelines increasingly advocate for maintaining absolute mean arterial pressure t...
- BiologyOpen access
卒中后抑郁与焦虑是卒中后高发神经精神并发症，可延缓神经康复，增加复发及死亡风险。该病临床漏诊率较高，缺乏早期特异性标志物，传统药物起效慢且不良反应明显。外泌体作为一类直径30~150 nm的细胞外囊泡，稳定性强，可穿透血脑屏障，携带多种蛋白质及微小RNA介导细胞间通讯，参与卒中后脑微环境重塑...
- Health & Medicine
Abstract The reductive coupling of alkynes and alkenes has emerged as a straightforward protocol for C–C bond formation from readily available feedstocks. Herein, we report a phosphine-mediated photocatalytic defluorinative reductive coupling of alkynes and trifluoromethyl alkene...
- Biology
CONTEXT: Inhibiting phosphodiesterase (PDE) activity to increase cyclic adenosine monophosphate (cAMP) concentrations is a core strategy in artificial sperm activation. PDE3, a key member of the PDE family, comprises two subtypes, PDE3A and PDE3B. However, their specific expressi...
- Society & EconomicsOpen access
The Internet as Precedent: Architectural Lessons for Federated Computing
This technical note examines the Internet as an architectural precedent for Federated Computing. The analogy lies in preserving local autonomy by making only the conditions required across boundaries explicit. It is not a proposal for a Federated Computing protocol stack, nor a d...
- Engineering & TechnologyOpen access
Error Indicators and Adaptivity for a Least-Squares Method Applied to the Monge-Ampère Equation
Abstract We introduce novel a posteriori error indicators for a nonlinear least-squares solver for smooth solutions of the Monge-Ampère equation on convex polygonal domains in $$\mathbb {R}^2$$ R 2 . The theoretical analysis is carried out for smooth solutions. At each iteration,...