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iPROLEPSIS_Updated report on user research and co-creation process

This deliverable, D2.5 “Updated report on user research and co-creation process,” summarises how patients, healthcare professionals, and researchers have jointly shaped the development of the iPROLEPSIS Digital Care Ecosystem. The report presents the progress of user research and...

Synthesis of Quinazoline Derivatives and Mechanistic Approaches in Lung and Breast Cancers

The quinazoline/quinazolinone ring is known as a unique scaffold, and its derivatives possess a broad biological activity profile, including antibacterial, antifungal, anticonvulsant, anti-inflammatory, anti-HIV, and analgesic activity, primarily focusing on anticancer activity....

Investigation of the Detection Frequency of Demodex spp. in Marmara University Faculty of Medicine Students According to Mask Use and Personal Hygiene Habits During the COVID-19 Pandemic

Objective: spp. Methods: . Volunteers were asked to complete a questionnaire about their personal hygiene habits. SPSS v.16.0 (IBM Corp., Armonk, NY, USA) software was used to analyse the results. Results: spp. (p=0.036). Conclusion: spp. in the cheeks of individuals using medica...

Solvent‐Based Spray Coating in Pneumatic Conveying in a Dedicated Spray Chamber Using Rapid Prototyping Created Nozzles

ABSTRACT Coating processes are used in various industries to adapt the particle surface. Pneumatic conveying systems are already present in many particle processing plants for transportation. The dilute flow regime in the commonly used Wurster coater is also present. This article...

A Robust Sequential Acoustic Sensing Framework for Shallow-Water Meteorological Monitoring in IoUT

Passive acoustic monitoring of ocean surface wind speed and rainfall faces severe degradation in shallow waters due to multipath propagation and non-meteorological noise interference. To address these challenges within the Internet of Underwater Things (IoUT), this study proposes...

Double-Edged Political Connections: The Effects on Domestic and International Performance Under Weak Institutions

Abstract While political connections are commonly linked to positive effects on firm performance, much less is known about the contingencies that shape these benefits. This study examines the simultaneous differential effects of political connections on domestic and international...

QANDLI DIABETDA GLYUKOZA–INSULIN DINAMIK MODELINING MATEMATIK TAHLILI VA PARAMETRLAR SEZGIRLIGI

Ushbu tezisda qandli diabet sharoitida glyukoza va insulin miqdorlarining vaqt bo'yicha o'zgarishini matematik modellashtirish masalasi o'rganiladi. Glyukoza insulin o'zaro ta'siri oddiy differensial tenglamalar tizimi yordamida ifodalanadi. Modelda glyukozaning organizmga kirish...

Markovian Dynamics Associated with d-Orthogonal Polynomials and Generalized Birth and Death Processes in Multiple-Life Insurance

We construct upward skip-free continuous-time Markov chains from finite-band recurrences associated with d-orthogonal polynomial systems. In the alternating-sign chamber, the recurrence yields an order-d generalized birth–death generator with one upward and at most d downward jum...

Boosting the Solar Water-Splitting Performance of a CuO Photocathode via Synergetic Interfacial Hole Extraction and Surface Electron Collection

Abstract P-type cupric oxide (CuO) is a promising photocathode material for solar hydrogen production, whereas its practical application is severely limited by constrained photoelectrochemical (PEC) performance and poor photostability. Herein, an integrated NiO/CuO/CuS photocatho...

Contralateral repeated bout effect in the triceps surae after unilateral heel drop exercise at 2- and 7-day interbout intervals

Abstract Purpose A single bout of unaccustomed eccentric exercise can protect against subsequent strength loss and soreness, with protection sometimes transferring to the unexercised contralateral limb. The contralateral repeated bout effect (CL-RBE) may be relevant for muscle–te...

Cosmological Constraints on the Formation and Survival of Small Hydrogen

The paper investigates the possibility of small hydrogen (SH) formation in the early Universe during an interval of about 10–80 s after the Big Bang. Assuming that SH exists as proposed by the author earlier, the current study examines the cosmological conditions under which the...

Impact of alcohol consumption on helicobacter pylori infection in patients with functional dyspepsia: a prospective observational study

Helicobacter pylori infection is a major cause of dyspeptic symptoms, but its association with alcohol consumption remains controversial. Few prospective studies have evaluated this relationship in patients with functional dyspepsia undergoing upper gastrointestinal endoscopy. Th...

Interpreter use in Nordic paediatric oncology care – a multicentre cross-sectional study

BACKGROUND AND PURPOSE: Tailored, language-appropriate information is fundamental for children and their families in paediatric oncology, influencing both the quality of care and clinical outcomes. Yet, for families who speak another language, interpreter services are not used to...

The Complete Two‑Weight \(\mathbb{Z}/5\mathbb{Z}\) Goemans–Linial Cone

For the weighted Cayley graph on \(\mathbb{Z}/5\mathbb{Z}\) whose difference‑\(\pm1\) edges have weight a and difference‑\(\pm2\) edges have weight b, we determine the uniform‑demand sparsest cut and the Goemans–Linial relaxation for every \(b\ge 0\) with \(a+b>0\). Both values a...

Drug−Drug Salts of Rucaparib with Nonsteroidal Anti-Inflammatory Drugs: Crystal Structures, Intermolecular Interactions, Solubility Enhancement, and Antitumor Activity

Abstract Rucaparib (RUCA) is an orally administered PARP inhibitor with an important clinical value in cancer therapy, but its poor aqueous solubility remains a major challenge for improving its dissolution behavior and pharmaceutical performance. In this study, drug−drug salt fo...

From Conflict to Coordination: Children as Strategic Problem Solvers in Social Dilemmas

Human cooperation requires resolving social dilemmas—situations in which individual interests conflict with what is best for the group. A growing body of work has begun to explore how children develop and implement solutions to these conflicts, shedding new light on the developme...

Breaking the black box of SEAA: the internal drivers of authentic ESG performance

Purpose In response to calls for more critical paradigms in Social and Environmental Accounting and Accountability (SEAA), this study challenges the treatment of corporate sustainability as a “black box.” We investigate the internal mechanisms that drive authentic Environmental,...

Potential Harms of Ocular and Periorbital Topical Vitamin A Application: A Systematic Review and Meta-Analysis

Purpose: Topical vitamin A derivatives (retinoids) are widely used for dermatologic and cosmetic indications and are often applied to the face and periorbital region. Although vitamin A is essential for epithelial integrity and tear film homeostasis, concerns exist regarding pote...

Towards Sustainable Recovery of Phenolics, Proteins, and Arabinoxylans from Brewer’s Spent Grain Through Deep Eutectic Solvents: Extraction Strategies, Structure–Function Relationships, and Food Biorefinery Perspective

Brewer’s spent grain (BSG) is the primary by-product of the brewing industry and a low-cost lignocellulosic resource rich in phenolics, proteins, and arabinoxylans (AXs). Conventional recovery methods using acids, alkalis, and organic solvents often involve energy-intensive proce...

The making of digital rangelands: Navigating the implications of rangeland datafication and smartification in Kenya

A shift is occurring in how the global environmental community understands and talks about rangelands. Long seen as economically unproductive and environmentally degraded environments, rangelands are now being recast as sources of untapped ecological benefit and climate optimism....