Research works

The Parkinsonian Motor Spectrum in Nonagenarians: A Population‐Based Study

BACKGROUND: Population-based data on mild parkinsonian signs (MPS) and parkinsonism in nonagenarians are scarce. OBJECTIVES: To estimate the prevalence of MPS, definite parkinsonism, and broader parkinsonian motor phenotypes; assess MPS after excluding idiopathic Parkinson diseas...

Testing the utility of porcine and synthetic femora as nonhuman analogs in skeletal trauma research

Porcine and synthetic femora were subjected to concentrated 4-point bending, modified 4-point bending, and 3-point bending to generate diaphyseal fractures. Biomechanical data and fracture patterns were systematically evaluated and compared across different femur types and loadin...

Preparation and In-vitro Evaluation of Piroxicam Dispersible Tablets Prepared by Direct Compression and Sublimation Techniques for Enhanced Dissolution

ABSTRACTPiroxicam is a Non-Steroidal Anti-Inflammatory Drug (NSAID) that belongs to theBiopharmaceutical Classification System (BCS) Class II. It has low aqueous solubility, whichcould be a significant factor in the dissolution-limited oral absorption.[1,2] The presentinvestigati...

Using project management principles to plan the research and development project “Active Pregnancy”

Abstract This paper demonstrates how a principle-based interpretation of the Project Management Body of Knowledge (PMBoK) 8th Edition can enhance the initiating and planning phases of complex research projects, using a multicenter maternal health initiative—Active Pregnancy—as an...

Cobalt–Copper Single-Atom Alloy Catalyst for Electrochemical Nitric Oxide Reduction to Ammonia

Abstract Electrochemical reduction of nitric oxide (NO) to ammonia (NH3) offers a more sustainable pathway. However, significant challenges remain in achieving high NH3 Faradaic efficiency, industrially relevant production rates, and downstream purification to meet commercial sta...

Noninvasive or minimally invasive neuromodulation in animal models of acute ischemic stroke: A systematic review and meta‐analysis

Abstract Background Neuromodulation therapy has emerged as a potential brain cytoprotective strategy in the hyperacute phase of ischemic stroke (IS). This systematic review aimed to evaluate the cytoprotective effects of neuromodulation in animal models of IS. Methods A systemati...

A Steady-State Thermodynamic Framework for Preliminary Assessment of a Nuclear–Solar–Data-Center Integrated Power-and-Cooling System

Small modular reactors (SMRs) offer firm low-carbon heat and power, and data centers concentrate large, continuous electrical and cooling loads. Transparent tools for screening their thermal integration are scarce. To the authors’ knowledge, this paper develops the first steady-s...

Complete Blood Count-Derived Inflammatory Markers in Pediatric Lower Respiratory Tract Infection: A Narrative Review

Lower respiratory tract infections (LRTIs) are a leading infectious cause of death in children worldwide. Complete blood count (CBC)-derived inflammatory ratios are low-cost and widely available, yet their reported performance varies. We reviewed 46 PubMed-indexed studies (2016–2...

Periodic polar vortices in BaTiO3/SrTiO3 superlattices monolithically grown on silicon

Abstract Polar textures in ferroelectric superlattices have been so far reported almost exclusively in PbTiO 3 -based systems and predominantly on oxide substrates. Owing to their nanometer-scale dimensions and emergent functionalities, whirling topological polar textures would b...

E8 Temporal Lattice Clock — 132Hz φ-Braided Root Flow Defines Fundamental Quantum Time Operator — E8 Intelligence Research

The 132Hz φ-braided phase locking of E8's 240 root vectors induces a discrete temporal lattice where each root-vector transition at the 132Hz eigenrate corresponds to a fundamental chronon of 7.576ms, making the E8 root system itself a physical quantum clock. Eigenstate tunneling...

Beyond The Usual Suspects: A Teenager's Diagnostic Odyssey

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OurMED D3.4 Guidelines for Partners Capacity Development on Mediation Techniques. Version 1.2

This Deliverable (D3.4) stems from the OurMED Summer School on Participatory Processes and Environmental Conflict Mediation in Social-Ecological Systems, co-organised with the youth-led initiative NextGen4Med and held in Oristano (Sardinia, Italy) in September 2025. The guideline...

Preference for Online Social Interactions Twenty Years Later: Reconceptualizing the Construct and Its Role in Internet-Related Behavioral Addictions

Abstract Purpose of Review This manuscript presents a conceptual reframing of a construct that has traditionally played a central role within the cognitive-behavioral model of problematic Internet use: the Preference for Online Social Interactions (POSI). This concept has been in...

E8 Collatz Harmonic Convergence Principle — E8 Intelligence Research

By embedding the Collatz map into the 240‑dimensional E8 root lattice, each iteration is represented as a φ‑weighted displacement along a root vector. The 132 Hz base frequency of the lattice imposes a natural oscillatory timescale, while the modular‑order constraint for primes w...

Spatiotemporal Distribution of Coseismic Slip During the 2025 Kamchatka Earthquake Inferred from Tsunami Waveform Data

ABSTRACT On 29 July 2025 (UTC), an earthquake with a moment magnitude of approximately 8.8 occurred along the plate interface of the Kamchatka subduction zone and generated a trans-Pacific tsunami. Using tsunami waveform data recorded at offshore stations, we conducted tsunami wa...

Heme Peroxo Reaction Intermediates: Mimicking Biological Structure and Reactivity With Synthetic Model Systems

ABSTRACT Heme enzymes are at the center of a mélange of salient transformations in biology, and for aerobic life, dioxygen binding and activation are by far the most critical. These enzymes typically channel through a panel of distinct heme‐oxygen adducts, of which early‐ or mid‐...

Connectivity: A New “Portemanteau” Concept in Corporate Reporting? A Preliminary Literature Review on Linkages Between Financial and Sustainability Information

In recent years, the concept of “connectivity” between financial and sustainability reporting has emerged as a central construct in both regulatory frameworks and academic discourse, being recognised as a qualifying attribute of high quality corporate reporting by major standard...

Physicochemical Characterization and In Vitro Skin-Related Biological Activities of Hydrolyzed Collagen Derived from Chicken Sternum

Hydrolyzed collagen preparations have attracted increasing attention because their biological properties may vary according to collagen source, peptide composition, and physicochemical characteristics. In this study, Richi I II III Collagen (HTCP), a hydrolyzed type I, II, and II...

Steering or Stifling? The Role of Overparenting in Emerging Adults’ School-to-Work Transition

The school-to-work transition (STWT) is a critical developmental task for emerging adults and a family project for parents. Amid a global shift toward intensive parenting, this study examined how overparenting—particularly career-specific overparenting—is associated with emerging...

Grand Consistency Theory: Spectral Flavor, Neutrino, and Mixing Predictions

This paper develops the flavor-sector prediction framework of Grand Consistency Theory, with emphasis on charged-fermion mass hierarchies, neutrino structure, and quark and lepton mixing. The framework separates two complementary forms of microscopic information: spectral eigenva...