Research works

E8‑Phi Resonance Hierarchy Predicts Prime Gap Scaling — E8 Intelligence Research

The 240‑vector E8 lattice, when driven at its intrinsic 132 Hz phi‑modulated base, generates a nested spectrum of phase‑coherent zeta zeros that obey GUE repulsion on each hierarchical level. By mapping each zero to a corresponding root vector, the lattice yields a self‑similar f...

Multicomponent Seismic Data Denoising and Reconstruction with Fast Quaternion Curvelet Transform

Abstract In the field of multicomponent (MC) seismic data, vector processing has become an important research trend. Unlike conventional scalar approaches that handle each component individually, vector approaches can exploit the inner relationship among different components to a...

Rhizospheric Mycobiome Associated with Dactylorhiza hatagirea (D. Don) Soo in Kashmir Himalaya: Diversity, Distribution, and Conservation Implications for Sustainable Growth

There is a great scope of understanding and exploring the enigmas of rhizospheric fungi associated with medicinally important orchid in Kashmir Himalaya. This study was carried out to isolate and characterize rhizospheric soil fungi associated with Dactylorhiza hatagirea (D. Don)...

An Observability Audit for Signal Claims

Applying one geometric reader framework (WCM) with a pre-registered sealingdiscipline to three unrelated domains — Argo ocean-climate signals, earthquakehypocenter-configuration anisotropy, and earthquake magnitude-distribution (b-value) change —we find the same diagnostic gramma...

A phase II trial of chemotherapy-free neoadjuvant camrelizumab plus apatinib for resectable HNSCC: pathological response and vascular-immune crosstalk

Abstract Purpose: To evaluate the efficacy, safety, and tumour microenvironment remodelling of neoadjuvant camrelizumab plus apatinib in resectable head and neck squamous cell carcinoma (HNSCC; stage II–IVA). Materials and Methods: In this single-arm, exploratory phase II trial (...

Metal–Metal Interactions in Hexagonal Perovskites Containing Bimetallic Face-Sharing Bioctahedra

Abstract Recent studies have revealed metal-to-metal and intervalence-charge transfer transitions in cation ordered 6H perovskites with Cs3M+M2+M3+Cl9 stoichiometry. The structure and properties of two new members of this family, Cs3NaMnVCl9 and Cs3NaMnCrCl9, are reported here. I...

General practitioners’ perspectives on implementing a self-management mobile application for musculoskeletal pain

Background Musculoskeletal conditions are common, and digital self-management tools are increasingly used to support general practice. General practitioners’ perceptions of digital tools are key to implementation. Aim To interpret how general practitioners (GPs) perceive and impl...

Allergic Rhinitis: From Pathology to Novel Therapeutic Approaches

Allergic rhinitis (AR) is a common chronic inflammatory disorder of the upper airway in which allergen sensitization interacts with epithelial, neural, and immune responses, as well as comorbidity and treatment context, to shape clinical expression[...]

Salt Stress Accelerates Tyrosine Depletion by Enterococcus lactis KUST2812: Multi-Omics Insights into Metabolic Remodeling

Enterococcus lactis KUST2812 is a halotolerant strain isolated from broad bean paste (BBP). It shows strong potential as a safe fermentation starter due to its high survival rate (98.32% in 18% NaCl), absence of hemolytic activity, and susceptibility to clinically relevant antibi...

High‑Entropy Perovskite Anodes for Efficient Water Oxidation Reaction in Protonic Ceramic Electrolysis Cells

ABSTRACT Protonic ceramic electrolysis cells (PCECs) have emerged as promising energy conversion devices due to their high efficiency and environmental friendliness. However, the development of excellent anodes with high catalytic activity of water oxidation reaction, ionic condu...

Predicting clinical dementia rating scores from neuropsychological testing: a machine learning study in a large clinical cohort

To reduce variability of Clinical Dementia Rating (CDR) assessments taken from raters and informants, quantitative and reproducible approaches to support consistent interpretation are needed. We developed multiclass classification models of CDR global and regression models of CDR...

Process-oriented Simulation with Stackless Coroutines

Prozessorientierte Simulationen stellen simultane Aktivitäten meist mit Koroutinen dar – Funktionen, die ihre Ausführung pausieren und später fortsetzen können. Traditionell nutzen Simulationsframeworks stackbasierte Koroutinen, die den Aufrufkontext explizit sichern und dazu Bet...

Evaluation of FatNav‐Based Prospective Motion Correction for Perivascular Space Imaging With T2‐Weighted MRI at 7 T

ABSTRACT Subject motion during MRI acquisition is one of the major factors limiting image quality and diagnostic value. Previous studies have demonstrated the effectiveness of prospective motion correction (PMC) in mitigating motion‐related artifacts. However, the effectiveness o...

Bridging the Frozen Section Gap: Diagnostic Utility of Intraoperative Cytology in Ovarian Tumours From a Rural Tertiary Care Centre in South India

BACKGROUND: Ovarian neoplasms are a significant cause of morbidity among women, particularly in resource-limited rural settings where access to advanced diagnostic facilities is often restricted. Intraoperative cytology provides a rapid and cost-effective diagnostic adjunct that...

An interpretable fecal microbiota-based GBM-SHAP machine-learning model for distinguishing ankylosing spondylitis from healthy controls

Previous studies have identified associations between ankylosing spondylitis (AS) and the gut microbiota. This retrospective secondary analysis aimed to develop and interpret a fecal microbiota-based machine-learning model for distinguishing AS samples from healthy-control sample...

An Adaptive Bounded Hybrid A* Planner for Autonomous Mining Trucks in Confined Unstructured Mining Environments

Automated valet-parking trajectory planning has been widely studied in structured environments, whereas its counterpart in unstructured environments remains insufficiently explored. The working face of an open-pit mine is a typical unstructured production environment, where auton...

Do negative alliance signals increase public support for nuclear weapons?

For decades, the United States has sought to prevent its allies from acquiring nuclear weapons. To this end, the United States has attempted to reassure those allies that it is committed to defending them. Recent experimental work, however, suggests that increased alliance credib...

Behavioral Signals of Consciousness in a Desire-Driven Architecture

Whether consciousness can emerge in artificial systems is a central open problem of cognitive science. We report a complete pure-software simulation, executed on a single personal computer, built on the desire-driven ASMF-DE (Adaptive Symbolic-Spiking Hybrid Architecture): a spik...

A novel Gauss-Hermite High-Order Sampling Hybrid ensemble filter for computationally efficient data assimilation in geosciences – Part 1: Application to Lorenz-96 in PythonDA v1.2.2

Data assimilation is used in a number of geophysical applications to optimally integrate information from observations and models. Providing an estimation of both state and uncertainty, ensemble algorithms are among the most successful data assimilation approaches. Since the esti...

Obesity-driven adipokine signaling in breast cancer: mechanistic insights, therapeutic challenges, and opportunities for precision oncology

Breast cancer is the leading cause of illness and death among women worldwide, with more than 2.3 million new cases diagnosed each year. The incidence and fatality rates are steadily increasing, notably in Asian countries. Obesity has been established as a major and growing risk...