Research works

Management of Adverse Events Associated with MET TKIs in Patients with Advanced NSCLC: A Podcast Discussion

MET exon 14 (METex14) skipping is observed in approximately 3–4% of patients with non-small-cell lung cancer (NSCLC). These patients are typically older and may or may not have a history of tobacco use. Several small molecule MET tyrosine kinase inhibitors (TKIs) have been develo...

Scour reduction performance of multi-layer collars around a cylindrical monopile

Local scour around offshore wind monopiles can reduce foundation embedment and threaten long-term structural performance. This study experimentally investigates single-, double-, and triple-layer collar systems under steady clear-water currents, with emphasis on the effects of co...

Physical activity in advanced urological cancers undergoing immune checkpoint inhibitor treatment: a qualitative study exploring patient perspectives and experiences

Physical activity (PA) can improve health and treatment outcomes in cancer patients. However, patients with advanced cancer undergoing immune checkpoint inhibitor (ICI) therapy often experience debilitating side-effects that impact PA participation. Because PA experiences in pati...

Odd-Parity Crystalline Electric Field and Multipoles in Icosahedral Quasicrystal and Approximant: Magnetic Toroidal and Electric Dipoles in Ce-Based Systems

Quasicrystals (QCs) lack periodic arrangement of atoms but possess unique structural order distinct from periodic crystals and random systems. The electronic property is far from complete understanding. Here we have formulated not only even-parity but also odd-parity crystalline...

Does child exposure to different discipline types vary by religion of caregiver in religiously diverse Trinidad and Tobago?

Background Some United States' (US) studies report that children in Conservative Protestant households are more exposed to physical punishments than children in other Christian and non-religious households. However, few studies examine the relationship between caregiver religion...

Progress in deformation mechanisms and emerging functionalities of metastable β titanium alloys: Insights from advanced characterizations

Metastable β titanium alloys, characterized by diverse microstructural evolution due to a high content of β stabilizers, offer great potential for achieving high multifunctionality, such as excellent strength and ductility combination, biocompatibility, superelasticity, shape mem...

The deep operator finite element method: A discrete variational neural operator for elasticity under variable loading

Learning solution operators for parametric partial differential equations is essential for real-time simulation and engineering analysis. However, existing physics-informed neural operators often suffer from unstable training due to numerical quadrature errors, sampling variabili...

Geometry-engineered heat sinks for enhanced cooling performance in immersion-cooled servers

This study introduces a novel geometry-engineered dual-CPU heat sink framework for single-phase immersion liquid cooling (SPILC) servers, addressing the limitations of uniform designs that ignore the distinct thermal-hydraulic conditions of upstream and downstream CPUs. The origi...

Decentralized microphone pair selection for steered response power based localization in wireless acoustic sensor networks

Abstract In distributed microphone arrays, using all microphones for sound source localization (SSL) significantly increases computational complexity. In wireless acoustic sensor networks (WASNs), this challenge is further compounded by the energy and bandwidth required to exchan...

The splicing factor SPR2 interacts with the RNA-binding protein PPR8 to facilitate mitochondrial intron splicing and is essential for maize seed development

Intron splicing plays a crucial role in organellar gene expression in plants, yet its mechanism remains poorly understood. We previously reported a small PPR protein, SPR2, which is a general splicing factor in the splicing of over half of the mitochondrial introns via interactio...

A binomial precision method for compound interest

This document presents a simple method to calculate compound interest using binomial expansion. Unlike the standard formula, this approach lets you choose how accurate you want the answer to be by controlling the number of terms used. It also gives a clean, easy rule for deciding...

Research on Multi-Point large strain measurement sensors based on flexible thin Films and fiber Bragg Gratings

To achieve highly sensitive distributed measurement of large strains, this paper proposes a surface-attached FBG array sensor based on a flexible PDMS/SiO 2 substrate. The sensor structure is designed, and a finite element model of the flexible thin-film substrate and the S-shape...

“How can I help you learn?” Incorporating emotions into parents' support of young children's self-regulated learning at home and school during prolonged crisis

Background Parents apply their knowledge of cognition, emotion, and behavior (metacognition, metaemotion, and metabehavior) to provide children external regulation to achieve learning goals. Aims Two studies examined how parents' metaprocesses shape children's self-regulated lear...

Combined effects of abdominal binders and TENS on post-operative pain, distress and constipation in puerperium period after cesarean section

The abdominal binders and transcutaneous electrical nerve stimulation (TENS) are widely used by clinicians for pain, wound healing and in stabilization. However, these benefits have not been properly investigated in women who have undergone cesarean delivery. To determine the com...

Physics-constrained large language model-assisted optimal scheduling approach for hydro-wind-solar systems considering multi-level backwater effects

Multi-level backwater effects couple downstream reservoir water levels with upstream tailwater levels and effective heads, which complicates the long-term coordinated scheduling of cascade hydro–wind–solar systems. This study addresses this scheduling problem by developing a phys...

Heterogeneous impact of household resilience on food and nutrition security: evidence from Senegal

Abstract This study investigates the heterogeneous impact of household resilience on food and nutrition security, using household-level data from Senegal. We use the Resilience Index Measurement and Analysis II (RIMA-II) framework to capture household resilience capacity. We empl...

Left ventricular end-diastolic diameter to body surface area ratio as a continuous risk marker in left ventricular non-compaction with a dilated phenotype: a multicenter cross-sectional study

Dilated cardiomyopathy (DCM) is a risk factor for poor outcomes in patients with left ventricular non-compaction (LVNC). This study aims to identify key factors associated with the DCM phenotype in LVNC and develop a risk stratification model. This multicenter cross-sectional stu...

Effect of Cell-Free Supernatant from Lacticaseibacillus paracasei on the Nutritional, Oxidative, and Microbiological Quality of Sous-vide Cooked Red Deer Meat

Game meat, including red deer ( Cervus elaphus ), is valued for its high protein content and favorable lipid composition but remains highly susceptible to oxidative deterioration, which limits its technological stability during processing and storage. Natural clean-label strategi...

A Multiplatform Chemical Perspective on Coffee Identity: Interplay Between Origin, Cultivar, and Fermentation Time

Abstract Green coffee bean chemistry is shaped by the geographic origin, plant genetics, and post-harvest processing, but their relative contributions across complementary chemical layers, within a single, tightly controlled context, remain comparatively underexplored. We applied...

Death anxiety and its associated factors among palliative care nurses in China: a multicenter cross-sectional study

To investigate the current status of death anxiety among palliative care nurses, explore its associated factors based on the Conservation of Resources theory, and provide an empirical reference to inform future targeted clinical interventions. A multicenter cross-sectional study...