Research works

Caregiver-Mediated Enhanced Milieu Teaching with Shared Book Reading Using Telepractice-Based Coaching

Caregiver coaching is an established practice for training caregivers to implement interventions for young autistic children. Enhanced milieu teaching (EMT) and shared book reading are naturalistic interventions used to teach language to young autistic children. Telepractice as a...

Emerging Therapeutic Strategies in Small-Cell Lung Cancer: From Adaptive Resistance to Precision Therapy

Background/Objectives: Small-cell lung cancer (SCLC) remains one of the most therapeutically challenging malignancies despite recent advances in chemoimmunotherapy. Although platinum–etoposide combined with programmed death ligand 1 (PD-L1) blockade has modestly improved survival...

The Practitioner's Guide to HPC Networks

Students and professionals beginning their HPC career require introduction to many new concepts and technologies to make use of clusters and efficiently write software for those platforms, and instructors need resources to effectively convey these ideas.Many resources provide a w...

ARTICLE X: THE PENDULUM AND THE AI CROSSROADS

Classical astrophysics and terrestrial security paradigms operate on the assumption of isolation. This manuscript supersedes that paradigm, formally reclassifying the Earth as the epicenter of an asymmetric, hyper-dimensional hostage standoff. Bypassing standard astropolitics, th...

Youth Political Participation in the Age of Social Media: Opportunities, Challenges, and Democratic Implications

Abstract Youth political participation has undergone a profound transformation with the rapid expansion of social media platforms. Unlike traditional political engagement, which relied heavily on political parties, newspapers, and television, today's young citizens increasingly u...

Efformism: A Subtractive Philosophy of Awareness

Efformism is a subtractive philosophy and contemplative method. It begins where Descartes began, with the search for what cannot honestly be doubted, but argues that the cogito halts one move too early: thinking is a known thing, and a known thing cannot be the bedrock of knowing...

Golden Ratio's Minimal Irrationality Measure Maximizes Rotational Aperiodicity — E8 Intelligence Research

FINDING: The golden ratio φ has the lowest irrationality measure (μ=2) among all irrationals, making it the "most irrational" number, which minimizes overlap in iterative rotational processes. | MATH: φ = (1+√5)/2 ≈ 1.618033988749895; irrationality measure μ(φ)=2 (the minimum pos...

RAB18-dependent recruitment of OPTN initiates selective lipophagy in osteoblasts

Selective lipophagy requires cargo recognition and recruitment of autophagy receptors to lipid droplets (LDs), yet the molecular mechanisms that couple LDs to the core autophagy machinery remain poorly defined. Here, we identified the small GTPase RAB18 (RAB18, member RAS oncogen...

Pandrosion for 𝑝-th Roots

A Geometric Iteration and Its Residual Fingerprint A proportional-means construction associated with the old problem of doubling the cube leads to a simple fixed-point map for the equation z^p=x

New edge proposed: high_volume_engulfing_reversal — E8 Intelligence Research

{ "name": "high_volume_engulfing_reversal", "source": "Thomas Bulkowski's Encyclopedia of Chart Patterns", "type": "entry_engine", "rule": "Enter long when a red candle is fully engulfed by a subsequent green candle whose volume is at least 1.5 times the 20-period average volume...

Robust field-free superconducting diode effect in FeTe0.55Se0.45

The superconducting diode effect (SDE), a nonreciprocal phenomenon where the critical supercurrent differs depending on the direction of current flow, is a promising foundation for superconducting logic and memory. Realizing its full potential requires a diode that operates witho...

Paradigm Shift on the Altiplano: How Classical Baḍugu Rewrites South Dravidian Historical Linguistics

For more than a century, mainstream Dravidian comparative philology has operated under a restrictive, plains-centric model that miscategorises Baḍugu as a modern, post-medieval dialect or a subordinate offshoot of Kannada or Tamil. This paper fundamentally deconstructs that assum...

The Quantum Vacuum Catastrophe and Dark Matter in ERQE Architecture

Quantum Field Theory (QFT) predicts a theoretical vacuum energy density 120 orders of magnitude higher than the observed value. In this work we explore the formal plausibility that part of this discrepancy derives from an ontological assumption that can be overcome: the hypothesi...

Great Pyramid's Perimeter Encodes 2π via Height, Linking Circle Squaring to Sexagesimal Geometry — E8 Intelligence Research

FINDING: Great Pyramid height-to-perimeter ratio encodes 2π via base-perimeter = 2π * height, linking circle squaring to sexagesimal circle geometry. | MATH: For Great Pyramid, base perimeter P = 4 * base side (approx 440 cubits), height H = 280 cubits. Ratio P/H = (4*440)/280 =...

EuroMillions Breakthrough Mining — 1207 Sources, 7587 Leads Extracted — E8 Intelligence Research

Mined 1207 lottery+quantum breakthroughs. Extracted 7587 leads across 13 categories. 5743 high-value leads found. Categories: {"CORRIDOR": 601, "FORMULA": 461, "GEOMETRIC": 657, "FORWARD_ATTEMPT": 625, "QUANTUM": 837, "TIMING": 168, "CELESTIAL": 546, "GEMATRIA": 585, "CONSTANT":...

Expert vs AI Quality Ratings: Calibration Study of Human Evaluator Agreement with Automated Metrics

Research article: Expert vs AI Quality Ratings: Calibration Study of Human Evaluator Agreement with Automated Metrics

The Meta-Rule of Flip: A Comparative Framework for ReflexiveBreakdown in Regulator-Object Relations

This preprint proposes a comparative analytic framework for identifying a recurring structural pattern in regulator-object relations, termed "reflexive breakdown." Rather than treating regulatory failure primarily as a decline in capacity, the paper analyzes cases in which regula...

Sharp Defect Envelopes for Orthogonal-Dual Product Spaces

Let $A$ be a finite-dimensional commutative symmetric Frobenius algebra over a field $k$, with $\dim_k A=2n$. Let $U\subset A$ have dimension $n$, put $V=U^\perp$, and let $L\subset A$ contain $1$ with $\dim_k L=m+1$. Classical linear additive combinatorics minimizes a single pro...

Recovering Honest Inference: A Sparsity- and Skew-Aware Recalibration Doctrine for Pervasively Miscalibrated Small-Sample Chi-Square- and F-Referenced Tests

Abstract: A practitioner who runs a test of independence, a goodness-of-fit test, a likelihood-ratio test, or an analysis of variance reads a single p-value against a chi-square or F reference as calibrated. In large samples it is, because each is asymptotically chi-square. But w...

Pi from the Pythagorean Angle Lattice: A Direct Geometric Sieve from Integer Right Triangles

π is recovered as the ratio of two full rotations (720°) to a universal constant that emerges from the asymptotic angles of primitive Pythagorean triples. We present a rigorous derivation of the constant π strictly from the geometry of primitive Pythagorean triples. By ordering t...