Research works
The research papers we track — the newest first. Works with a plain-language summary link to it.
126741 work(s)
- Biology
Abstract Accurate single-CpG methylation analysis in dense regions is critical for cancer diagnostics but challenged by adjacent CpG interference. Here, we developed EPICATCH, an interference-tolerant ratiometric Cas13a biosensor to overcome this limitation. Exploiting LbuCas13a′...
- Materials & Energy
Abstract Multimetallic nanoparticle catalysts present exciting opportunities to achieve sustainable chemical transformations based on their unique structure that can lead to enhanced reactivity, especially when a blend of functional metal atoms is incorporated. The fundamental sc...
- BiologyOpen access
Salt stress is a major abiotic stress that restricts the growth and development of maize, often leading to irreversible yield losses when it occurs at flowering. To dissect the genetic basis of flowering-related traits under salt stress, a natural panel of 395 maize inbred lines...
- Materials & Energy
Abstract Controlling the spatial distribution of photoluminescent molecules within constrained microenvironments remains a fundamental challenge in enhancing their photophysical properties. Herein, we demonstrate that the differential adsorption behavior of enantiopure and racemi...
- Society & EconomicsOpen access
The article examines how the concept of identity is expressed in the Uzbek language of historical and ethnological scholarship of the independence period. Three lexical resources are identified: the native derivative o‘zlik with its extension o‘zlikni anglash, the Arabic-derived...
- Physics & SpaceOpen access
One-dimensional photonic crystals (1D PhCs) are among the most fundamental building blocks of modern photonic devices owing to their simple, lithography-free architecture, ease of fabrication, and versatile optical properties. Their optical response can be reconfigured through ex...
- Engineering & TechnologyOpen access
HydroPrior: Offline LLM-Prior-Guided Residual Warning for Hydropower Bearing Vibration
Hydropower vibration monitoring requires early warnings with manageable inspection costs despite scarce verified fault labels. HydroPrior combines offline large language model (LLM) priors with lightweight residual-based warning. The LLM converts channel descriptions and training...
- Health & MedicineOpen access
Abstract Background RAS pathway mutations occur in ~ 40% of colorectal cancers (CRCs), with KRAS- and BRAF- mutant tumors exhibiting distinct mutational, transcriptional, and epigenetic landscapes. Advances in next-generation sequencing enable integrated analyses of multi-omics d...
- Health & MedicineOpen access
Genetic evidence for the psychosis continuum: polygenic score analysis
Background The psychosis continuum conceptualises psychotic phenomena as existing on a spectrum from subclinical experiences to psychotic disorders. Despite epidemiological and clinical evidence in support of this model, few studies have examined polygenic liability across the se...
- Health & Medicine
Electrolyte- and Catalyst-Free Electrochemical Synthesis of Unsymmetrical Diorganoyl Selenides
Abstract A facile electrocatalytic radical coupling of Katritzky salts with diselenides for the efficient synthesis of various alkyl aryl unsymmetrical selenides has been developed under mild conditions. This sustainable protocol is driven by renewable electrical energy, features...
- AI & Computing
Mobile network operator (MNO) data provide rich, high-resolution information that is valuable for a wide range of statistical analyses. In Germany, however, current data-privacy practices severely restrict the release of high-resolution datasets. This paper demonstrates that pert...
- AI & ComputingOpen access
Multilevel Embedding and Dropout for Improved 3D Object Detection in Autonomous Driving Systems
The balance between performance and model complexity in terms of time and storage is crucial fordeploying effective and practical autonomous driving systems. However, some recent advancements in 3D LiDAR object detection come at the cost of significant increases in computational...
- AI & ComputingOpen access
Effective lithological mapping and mineral exploration remain challenging in geologically complex and underexplored Precambrian terrains. This is particularly relevant to the Arabian–Nubian Shield (ANS), a Neoproterozoic orogenic belt extending across northeastern Africa and Arab...
- AI & ComputingOpen access
√2 as the Minimal Irrationality: Algebraic, Geometric, and Ontological Analysis
The number √2 occupies a unique position in mathematics. It is not merely the first proved irrationality, but the minimal irrationality in a strict sense, which we make precise. The work consistently unfolds the minimality of √2 through five independent criteria and shows that al...
- Society & EconomicsOpen access
How are innovation inputs and measured outputs distributed across the regions of a resource-dependent post-Soviet economy, and how closely do they correspond? We use a balanced official panel of Kazakhstan’s 17 regions for 2014–2025 (204 region–year observations) covering four in...
- Society & Economics
Geometric ornament as material knowledge: Ethnogeometric structures of spatial cognition
This article proposes a method for analysing recurring geometric relationships in Chalcolithic Botai material culture in northern Kazakhstan. Ornamented artefacts, dwelling architecture and settlement layout are examined without assuming a single symbolic code or historical conti...
- Health & MedicineOpen access
Abstract Purpose To determine whether upper respiratory tract co-detection of human rhino-/enterovirus is associated with a distinct clinical phenotype in children with Mycoplasma pneumoniae infection. Methods We analyzed 236 children with M. pneumoniae infection detected by mult...
- Health & MedicineOpen access
ABSTRACT Managing multidrug-resistant gram-positive infections is challenging, especially when prolonged therapy is needed for conditions like bacteremia, endocarditis, osteomyelitis, or other deep-seated infections. Oritavancin, a long-acting lipoglycopeptide, is increasingly us...
- Society & Economics
The Testimonium Flavianum , 1893–2025
This article responds to T.C. Schmidt, Josephus and Jesus: New Evidence for the One Called Christ (2025), which argues that Josephus’ account of Jesus and the first Christians ( Antiquities 18.63–64; the Testimonium Flavianum ) is authentic and that Josephus got his information a...
- Health & Medicine
Purpose: To characterize the behavior of single and combined intravitreal tamponade agents using magnetic resonance imaging (MRI), with emphasis on identifying the most effective materials and postoperative positioning strategies for complex retinal detachments involving both sup...