Research works

TMEM135 deficiency prevents intestinal lipid accumulation by coordinating lipid uptake and oxidation through ELOVL6-mediated PPARα activation

Abstract Excessive lipid accumulation impairs digestion and gastrointestinal function. Transmembrane protein 135 (TMEM135) is involved in lipid metabolism of various tissues. Here, TMEM135 deficiency increased intestinal lipid absorption through ELOVL6-dependent oleoylethanolamid...

Micro- and NanobubblesEnhance the Abatement of BiodegradableMicropollutants in Aged Biological Activated Carbon Filters

Abstract It has been demonstrated that the abatement of micropollutants in drinking water by biological activated carbon (BAC) filters with aged media deteriorates due to the decreased porosity and aerobic metabolism in dense biofilm. In this study, micro- and nanobubbles (MNBs)...

The Garden That Left No Trace: Virtual Reconstruction at the Evidential Minimum — a Conjectural Renaissance Kitchen Garden for Burg Schönebeck

Gardens are the most perishable class of built heritage. A demolished building leaves foundations, fragments, andusually documents; a garden leaves soil. When the garden in question was a working kitchen garden at a minorWestphalian castle — never painted, never engraved, never d...

Nanopore-ConfinedSub-Nanometer Co and Ni Specieson Porous Carbon Nitride for Efficient Water Electrolysis

Abstract Electrochemical water splitting is a promising route in clean energy production. Therefore, the development of efficient, stable, and cost-effective electrocatalysts remains highly desirable. Here, we report a facile nanopore-confinement strategy for growing well-dispers...

Machine learning–based screening tool for predicting the risk of oropharyngeal dysphagia in patients with ischemic stroke

Abstract Purpose Dysphagia frequently complicates recovery after stroke, necessitating effective predictive tools. This study aimed to develop supervised machine learning models to predict dysphagia risk in ischemic stroke patients. Method We retrospectively analyzed data from 10...

Dual-tracer 18 F-FDG and 68 Ga-DPI-4452 PET revealed distinct features of synchronous multiple renal cell carcinomas

A 66-year-old male presented with gross hematuria and a left renal mass. 18 F-FDG PET/CT revealed an FDG-avid mass in the mid-pole of the left kidney with renal vein tumor thrombus. The patient was subsequently enrolled in a clinical trial evaluating the carbonic anhydrase IX (CA...

Foodservice operator and implementation support practitioner needs for sustaining healthy food retail practices in Australian foodservice settings: findings from a national cross-sectional survey

Abstract Background Food outlet practices that support consumers in making healthier food and drink purchases (e.g. healthy product availability and promotion) are key strategies for improving population diets. To have lasting population health impacts, these practices must be su...

The Börekci Solar Antimatter Collector v6: A Liouville-Limited, Plasma-Magnet-Free Architecture that Closes on Demonstrated Trap Technology

Version 6 of the Börekci Solar Antimatter Collector is an audit-and-rebuild of version 5. Three physics errors in v5 are identified and repaired. (i) The collection area was taken as the area of a circle whose radius is the magnetic deflection radius. This violates Liouville's th...

Single-use bronchoscopes in contemporary respiratory practice: current evidence and clinical applications

Abstract This narrative review examines the evolving role of single-use flexible bronchoscopes (SUFBs) in contemporary respiratory medicine. SUFBs have become an increasingly important part of respiratory practice, particularly following the COVID-19 pandemic, which highlighted t...

Beyond Capital and Labour: The Firm as a Flow Architecture for Organizational Value Creation

Why do firms with similar capital, labour, technologies, and market access produce radically different outcomes? This conceptual paper develops a dynamical architecture of organizational value creation. It treats the firm as a cross-temporal flow architecture through which resour...

Breast reconstruction and breast cancer surgery in Brazil’s public health system: a nationwide interrupted time-series analysis, 2008–2024

Abstract Background Breast reconstruction is a key component of comprehensive breast cancer care, yet access remains uneven in many middle-income countries. In Brazil, federal policies have sought to expand reconstruction within the public health system (SUS), but long-term natio...

The Effects of Stop Sexual Harassment: a Cluster-Randomized Controlled Trial

Abstract Sexual and gendered harassment is prevalent among adolescents and associated with health outcomes. Evidence from randomized controlled trials of school-based interventions addressing such harassment outside dating contexts among students under 16 years is limited. This s...

PhosphorusChemistry and the Origin of Life: From N -PhosphorylAmino Acid to Protocell

Conspectus A central question in origin-of-life research is how biological macromolecules and cellular structures arose from simple precursors under prebiotic conditions. This review focuses on the chemical evolution model of N-phosphoryl amino acids (NPAAs) and their multifacete...

Comparative evaluation of Bacillus and Lactobacillus in cottonseed hull fermentation

Abstract Microbial fermentation is an effective approach to improving the nutritional value of cottonseed hulls and alleviating feed resource shortages. However, the interaction mechanisms between Bacillus and Lactobacillus within fermentation systems remain unclear. In this stud...

Decoupling geometry and topography reveals contrasting ecomorphological signals in carnivoran carnassial teeth

Abstract The lower carnassial tooth (m1) is a key innovation underlying the ecological diversification of Carnivora. However, their exceptionally diverse phenotypes result from both functional adaptation and phylogenetic inertia which challenges ecomorphological inferences. We in...

Systematic Tuning of Lattice Strain and Surface Structures of Platinum Alloy Nanowires for Enhanced Oxygen Reduction Performance

Abstract The development of nanostructured catalysts with improved oxygen reduction reaction (ORR) performance is pivotal for advancing high-performing polymer electrolyte fuel cells (PEFCs). In this study, we synthesized Pt-alloy nanowires with systematically tuned morphologies,...

Wireless Communication Evolution: A Comprehensive review of the Architecture, Technologies, Applications, Challenges, and Future Prospects of 6G

6G, the sixth generation of wireless communication, is expected to introduce exceptional technologies and use cases that once seemed fictional. Each generation of wireless communication systems has enabled the exchange of messages such as voice, video and other types of data betw...

Observational Phase-Coherent Residual Modulation in Type Ia Supernova Hubble Diagrams

We analyze a reported nonlinear-phase modulation in Type Ia supernovaHubble-diagram residuals, emphasizing visualization, cross-compilation phasecoherence, look-elsewhere effects, waveform choice, endpoint artifacts, andpassband systematics. In a reconstructed 7687-entry diagnost...

Charting the future of auditing: a global latent Dirichlet allocation-based exploration (1988–2024)

Abstract This study aims to identify key themes and research trends in auditing through a comprehensive analysis of 5961 Scopus-indexed articles published from 1988 to 2024. Latent Dirichlet allocation (LDA) was employed to uncover dominant themes and associated conceptual groupi...

Caregiver Perspectives on Implementation of Discharge Plans for Children With Medical Complexity

OBJECTIVE The quality of discharge processes impacts adverse outcomes post hospitalization for children with medical complexity (CMC). Perspectives of caregivers at risk for communication challenges (eg, non-English speakers, those with limited health literacy, immigrants) on und...