Research works

Loneliness trajectories surrounding mobility loss: The role of disability duration

Abstract Objectives Mobility limitations in later life can disrupt social engagement and increase loneliness, but trajectories may differ depending on whether limitations remain or individuals recover. This study examines loneliness trajectories around the onset of mobility limit...

The phantom colon: living in the delay of gut collapse

Abstract Ulcerative colitis (UC) is an inflammatory bowel disease that often demands losing the colon. It has been linked to the loss of microbiome diversity associated with the lifestyle, environmental, immunological, and metabolic processes of modern life. In the United States,...

Isotopic Engineering of Water Reactivity for Stable Aqueous Iron‐Metal Batteries

ABSTRACT The development of aqueous iron‐metal batteries (AIBs) is critically hindered by the severe parasitic hydrogen evolution reaction (HER) at the anodes and the resulting structural degradation of the cathode. Moving beyond conventional additive‐based approaches, this work...

Binary Cuntz Bridge Framework v1.0: Corrected Scale Relation and Conditional Spin(10) Phenomenology

This is version 1.0 of the Binary Cuntz Bridge Framework, released as a preliminary, non-peer-reviewed working paper. This version corrects and strengthens the scale relation by introducing a parametrized total suppression S_tot = S_bridge + Delta S. For the preferred branch sigm...

A Study on the Current Status of Ventilation Systems in Infection-Vulnerable Facilities and the Assessment of Airborne Transmission Risk of Respiratory Infectious Diseases

This study quantitatively assessed the airborne transmission risk of respiratory infectious diseases in infection-vulnerable facilities, focusing on the current status of their ventilation systems. Field investigations were conducted at 32 facilities across Korea, including long-...

The Financial Burden of Amyotrophic Lateral Sclerosis Diagnosis: Estimating Costs of Unnecessary Procedural Interventions and Exclusionary Testing

Background: People living with amyotrophic lateral sclerosis (ALS) experience diagnostic delays, involving multiple visits to neurologists and non-neurologist specialists. During this process, patients may be misdiagnosed and undergo unnecessary procedures. Additionally, ALS diag...

Assessment of degradation in Ion pair membrane high temperature PEM fuel cells using commercial and customized catalysts under varied operating conditions

High-temperature proton exchange membrane fuel cells (HT-PEMFCs) present considerable advantages, such as high energy efficiency and tolerance to fuel impurities; however, durability issues and catalyst costs remain major barriers to commercial adoption. This study systematically...

Paclitaxel-loaded nanostructured lipid carriers surface-functionalized with N6L for pancreatic cancer

Pancreatic ductal adenocarcinoma (PDAC) remains one of the most aggressive and lethal malignancies, with limited therapeutic options. Despite advances in chemotherapy, such as FOLFIRINOX and Abraxane® (nab-paclitaxel) combined with gemcitabine, these treatments show limited effic...

Offshore fish farming in exposed seas: A state-of-the-art review of challenges, potential solutions and numerical modelling

Global warming has accelerated the shift from nearshore to offshore aquaculture, where colder waters, improved water exchange, lower pen density, and reduced inter-pen infection risks provide more favourable conditions for sustainable fish production. However, offshore fish farmi...

The relationship of shift timing with emergency cesarean delivery rate, decision-to-delivery interval, and neonatal outcomes: a retrospective cohort study

Variations in obstetric care across different shifts may affect the timing of emergency interventions and perinatal outcomes. However, evidence on the combined relationship of shift timing with emergency cesarean delivery rate, decision-to-delivery interval (DDI), and neonatal ou...

Surface morphology, printing accuracy and flexural strength of 3D-printed zirconia posts with longitudinal microgrooves

Postcore restoration is essential for compromised teeth. Zirconia is a promising material due to its esthetics, strength, and radiopacity. Additive manufacturing, particularly advanced customized jetting (ACJ) technology, enables the fabrication of complex microstructures on zirc...

The KnoWellian EPOCH-2027: The Eradication of the Platonic Pathogen and the 31 Zero-Free-Parameter Derivations of the Geometric Ground State

Version 2.0 of The KnoWellian EPOCH-2027 represents the complete, closed-loop master synthesis of the KnoWellian Universe Theory (KUT), incorporating two major new appendices and critical cosmological expansions: Appendix A (The KUT Seed — Fee, fi, fo, fum): Introduces a formal b...

Differential modulation of rumen function and bacterial communities in lambs by silage type and nitrogen source

The present study evaluated the effects of sweet sorghum silage as an alternative forage and slow-release urea as a non-protein nitrogen source on ruminal function and bacterial communities in lambs, as determined by enzymes activity, fermentation profiles, and microbial communit...

Age-related and temporal patterns of blood pressure among male industrial workers in Shanghai: evidence from occupational health examinations, 2013–2023

Occupational health examinations provide repeated and standardized health data for workers under surveillance and may offer a valuable resource for long-term blood pressure monitoring. However, evidence on age-related and temporal patterns of blood pressure among occupational pop...

How Feasible is the Use of Saliva for Antiviral Therapeutic Drug Monitoring? A Systematic Review and Analysis

Immunosuppressed patients are susceptible to serious viral infections, often necessitating antiviral prophylaxis and/or treatment. Therapeutic drug monitoring (TDM) has been proposed to optimise drug exposure and clinical outcomes and is typically performed on full blood/plasma s...

Nursing students’ attitudes toward caring for dying patients: a quantitative study

End-of-life care is a fundamental component of nursing practice; however, many nursing students report insufficient preparation, emotional discomfort, and a lack of confidence when caring for dying patients. Cultural and religious factors may further influence students’ attitudes...

Cryo-instrumentation technique: a temperature-modulated approach to improve the mechanical performance of NiTi endodontic instruments

Background The mechanical behavior and shaping performance of heat-treated nickel–titanium (NiTi) rotary instruments are influenced by temperature-dependent phase transformation. Aim This study evaluated cryo-instrumentation technique, in which NiTi instruments are used under con...

Geospatial assessment of agrivoltaic feasibility in the Iberian Peninsula

This work investigates the feasibility of deploying agrivoltaic (AgriPV) systems in the Iberian Peninsula through an integrated geospatial assessment framework. The proposed methodology combines geospatial screening, agroclimatic and spatial datasets, crop suitability assessment,...

Thermo-hydraulic performance improvement of a shell-and-tube heat exchanger using perforated double-segmental baffles: A comparative CFD investigation

This study numerically investigates the thermo-hydraulic performance of a shell-and-tube heat exchanger (STHX) with three different baffle arrangements: conventional single-segmental (CSS), perforated double-segmental (PDS), and modified geometric baffle (MGB). Three-dimensional,...

Why are there so many different guidelines? A qualitative study of the low back pain policy landscape in Australia

Low back pain is a major cause of disease burden around the world. The sheer number and variety of back pain guidelines developed in Australia suggests that there are drivers within the low back pain care landscape to promote development of guidelines which are produced by a wide...