Research works

Elevated thyroglobulin due to a back musculature schwannoma in differentiated thyroid cancer: a case report

Case presentationOn 29 June 2021, a 36-year-old man with stage T4N1M0 differentiated thyroid cancer presented to the First Affiliated Hospital of Anhui Medical University for radioiodine therapy aimed at eliminating metastases.The patient had previously undergone bilateral radica...

Chinese expert consensus on extraintestinal manifestations of inflammatory bowel disease

Inflammatory bowel disease (IBD) is a chronic, relapsing, inflammatory condition of the gastrointestinal tract that primarily includes Crohn's disease and ulcerative colitis. Beyond the typical gastrointestinal symptoms, IBD is frequently associated with various extraintestinal m...

A Case of Hybrid Lower Limb Revascularization for Aortoiliac Occlusive Disease with Severe Bilateral Common Femoral Artery Calcification Occlusions

大動脈腸骨動脈閉塞症TASC II分類D病変のうち，腎動脈直下閉塞に加え両側総大腿動脈（CFA）高度石灰化閉塞を伴う症例では，確実な内腔およびアクセスの確保という点で治療戦略に工夫を要する。我々はそのような症例に対して，両側CFA血栓内膜摘除術と血管内治療を組み合わせたハイブリッド血行再建術を...

Whole-genome resequencing identifies a novel SNP associated with lumbar vertebrae number in Dezhou donkeys

The number of vertebrae is an economically significant trait in livestock, with variations in this trait directly influencing meat and hide production performance. Within the Dezhou donkey population, five distinct thoracolumbar vertebrae combinations have been identified (T17L5,...

Technology adoption drives entrepreneurial performance through integrated PEST factors supporting sustainable economic growth and innovation

Entrepreneurial performance in emerging economies is shaped not only by macro-environmental conditions but also by entrepreneurs’ ability to adopt and leverage digital technologies. However, empirical research remains limited in explaining how political, economic, social, and tec...

Clinical characteristics of the reduced bone mineral density subgroup among adults with type 2 diabetes mellitus: a retrospective cross-sectional study

Skeletal fragility in type 2 diabetes mellitus (T2DM) is incompletely represented by areal bone mineral density (BMD). We defined an operational reduced-BMD subgroup using routine hospital information-system data and examined whether routinely available clinical variables showed...

Association of the triglyceride-glucose index with prostate cancer risk and prognosis: a systematic review and meta-analysis

The triglyceride-glucose (TyG) index has emerged as a convenient and reliable surrogate marker for insulin resistance (IR) and has been linked to an increased risk of several malignancies. However, its association with prostate cancer (PCa) risk remains uncertain. We therefore co...

Analysis of Pharmacist Interventions during Remote Accompaniment to Physician’s Home Visits in a Medically Underserved Area: A Comparative Study with Conventional In-Person Practice

Participation of pharmacists during physicians’ home visits is effective in home healthcare. However, substantial practical barriers exist in regions where medical resources are unevenly distributed. This study sought to clarify the effectiveness and limitations of a hybrid onlin...

Exosomal microRNAs in tumor–heart crosstalk: nanobiological mechanisms and therapeutic implications

Exosomes are nanosized extracellular vesicles (30–200 nm) that function as natural nanocarriers for intercellular communication by transporting biological macromolecules, particularly microRNAs (miRNAs). These small, non-coding RNA macromolecules regulate gene expression post-tra...

Reliability and validity of the modified chinese version of new Cleveland clinic colorectal cancer quality of life questionnaire

The New Cleveland Clinic Colorectal Cancer Quality of Life Questionnaire (CCF-CaQL) was developed to assess postoperative quality of life (QoL) in patients with colorectal cancer (CRC). Since its introduction, it has been validated in several countries. This study aimed to evalua...

Genome-wide characterization of the SnRK gene family in jujube (Ziziphus jujuba Mill.) reveals that ZjSnRK7 and ZjSnRK9 may contribute to salt stress tolerance

During the plant life cycle, biotic and abiotic stresses critically influence survival and development. Sucrose non-fermenting 1-related protein kinases (SnRKs)-a conserved class of key signaling regulators-play a central role in stress response mechanisms shaped by long-term pla...

How long can suction drains be safely retained after surgery for musculoskeletal malignant tumors?

In orthopaedic surgery, prolonged suction drainage has been associated with an increased risk of infection, and drain removal within 24 h is generally recommended. However, whether this recommendation applies to musculoskeletal tumor surgery, which is often more invasive and asso...

Comparative evaluation of decision tree and random forest models for multi-class water quality classification of the Yamuna river

Monitoring the quality of water in rivers is important for environmental sustainability. This study presents a comparison of Decision Tree (DT) and Random Forest (RF) classifiers for multi-class classification of the water quality of the Yamuna River on the basis of temperature,...

Hybrid dynamic feature convolution with transformer fusion model for the detection of intrusion during manufacturing process

Intrusion detection is essential in contemporary manufacturing systems. These are vulnerable to various cyber threats due to the integration of cyber-physical systems and continuous data exchange. Traditional intrusion detection systems include statistical models and standard mac...

How reliable is percutaneous transforaminal endoscopic discectomy during the learning curve? A comparison of outcomes with microsurgical discectomy experiences

We aimed to share our early experience with percutaneous transforaminal endoscopic discectomy (PTED) during the initial phase of the learning curve and to compare its clinical and perioperative outcomes with microsurgical discectomy (MD) in selected patients with symptomatic lumb...

Magnetic fields and agro-industrial by-products as sustainable approaches to enhance carotenoid and lipid production by Rhodotorula mucilaginosa

This study aimed to evaluate magnetic fields (MF) and agro-industrial media as sustainable approaches to produce carotenoids and lipids by Rhodotorula mucilaginosa. Cultivations were carried out in shaken flasks with previously optimized agro-industrial media with sugarcane molas...

Dental caries among 12-year-old adolescents in shanghai: a cross-sectional study on prevalence, severity, and associated risk factors

This study aimed to assess the prevalence, severity, and associated factors of dental caries in permanent teeth among 12-year-old adolescents in Shanghai, China. A cross-sectional study was conducted in 2021 among 1,305 adolescents from six randomly selected districts. Clinical e...

An Action-masking and Self-labeling-based Learning Method for Block Sequencing and Bay Assignment Optimization in Shipbuilding Panel Lines

The block sequencing and bay assignment problem in a shipbuilding panel line is a complex combinatorial scheduling problem in which upstream serial processes and downstream parallel bay processes are coupled under multiple operational constraints. In practical panel-line planning...

Robust State Estimation via Dual-threshold NIS-based Kalman-FIR Switching

This study proposes a robust state estimation framework for discrete-time linear time-invariant systems using a statistically grounded switching mechanism between the Kalman filter (KF) and the optimal finite impulse response (OFIR) filter. While the KF provides minimum-variance...

Latent subtypes and gender differences in the comorbidity of depression and sleep disturbances among adolescents: insights from network analysis and latent profile analysis

This study aimed to explore potential subtypes, influencing factors, and gender differences in the associations between adolescent depression and sleep disorders. A cross-sectional study was conducted among adolescents utilizing the Center for Epidemiologic Studies Depression Sca...