Research works

The right time to quit: patients' experiences of smoking cessation support during COPD hospitalisation

Introduction Smoking cessation is a central component of disease management in chronic obstructive pulmonary disease (COPD). Hospitalisation provides an opportunity to initiate smoking cessation support. The present study aimed to explore how patients with COPD perceived the usef...

An openBIM–openGIS framework for route-aware embodied-carbon assessment in public building procurement

Urban construction supply chains contribute substantially to greenhouse-gas emissions and logistical inefficiencies, partly due to fragmented digital workflows between Building Information Modelling (BIM) and Geographic Information Systems (GIS). This study introduces an openBIM–...

Mantle heterogeneity drives spreading center dynamics at Arctic Mid-Ocean Ridge

The Mohns and Knipovich mid-ocean ridges in the Arctic Ocean are ideal settings to investigate the dynamics of spreading centers, being the region affected by intricate interplays between oblique plate kinematics and curved plate boundary geometry. Furthermore, significant mantle...

When the Introducer Becomes the Limiting Factor: A Technical Note on a Simple Modification to Facilitate Spinal Anesthesia With Pencil-Point Needles in Morbidly Obese Patients

Morbid obesity is associated with increased skin-to-dura distance, which may complicate spinal anesthesia using standard-length pencil-point spinal needles. We describe a simple technical modification developed during spinal anesthesia in a parturient with a body mass index of 40...

Hierarchical Enzyme Function Prediction Based on Structural Confidence and Active-Site-Aware Attention

Accurate enzyme function prediction is important for protein functional annotation, drug discovery, metabolic-pathway analysis, and synthetic biology. Although recent structure-based methods have improved Enzyme Commission (EC) number prediction, they still have several limitatio...

Moderate Biochar–Compost Mixture Is More Effective in Improving Biomass, Nutrient Fluxes, and Photosynthetic Outputs for Sustainable Land Restoration and Soil Fertility

ABSTRACT Soil nutrient depletion severely constrains crop productivity in degraded and saline environments. Strategies such as biochar–compost integration could be useful for sustainable agriculture and land restoration on a global scale. This study evaluated the effects of bioch...

Gas InvasionPatterns in Saturated Marine Sediments

Abstract Gas invasion into fluid-saturated marine sediments is relevant to various geophysical and environmental processes, such as the formation of gas hydrate reservoirs and their behavior during depressurization-based gas production. The link between pore-scale mechanisms and...

MACHINE LEARNING AND ARTIFICIAL INTELLIGENCE FOR THE DIAGNOSIS OF POLYCYSTIC OVARY SYNDROME (PCOS): A NARRATIVE REVIEW

Polycystic Ovary Syndrome (PCOS), now broadly termed as Polyendocrine Metabolic Syndrome, is one of the most common endocrine disorders among women of reproductive age, with high global prevalence ranging from approximately 6% to 21% depending on the diagnostic criteria applied,...

Co(Healthcare): Applied Continuity Architecture and Evaluation Pathways (Paper 10.2.1)

Paper 10.2.1 is a non‑canonical sub‑extension of Paper 10.2 in the DCE 10.x Continuity Geometry series. It translates the continuity geometry of the healthcare substrate into applied, operational, and measurable continuity architecture for real healthcare environments. The paper...

A Body Within a Body — Pregnancy, Personhood, and Inner Jurisdiction

This essay examines pregnancy as an embodied relation between unequal scales of life and asks how moral responsibility can recognize developing life without transferring jurisdiction over the pregnant body to another person or the state. It proposes inner jurisdiction—not as abso...

Addendum to NavMesh Cosmology: A Deterministic Derivation of the Total Baryonic Mass of the Universe via Spatial Computational Latency

In the foundational framework of NavMesh Cosmology, the 10^122 magnitude discrepancy of the Vacuum Catastrophe was resolved by redefining cosmological time as an emergent property of spatial computational latency, yielding a universal Slowdown Ratio (𝑆𝑟≈7.69×10^60) [1]. In this b...

Trifluoromethyl-Benzimidazole-Hydrazone Derivatives as Promising Selective Anticancer Agents: Synthesis, Cytotoxicity, and Molecular Docking Insights

Background/Objectives: Benzimidazole and hydrazone scaffolds are widely investigated in anticancer drug discovery because of their structural versatility and capacity to interact with multiple cancer-related targets. This study aimed to synthesize a series of trifluoromethyl-subs...

Weight and Glycemic Outcomes Following GLP-1 Receptor Agonist Therapy in People Living with HIV: A Retrospective Study at a Bronx Hospital

Background/Objectives: People living with HIV (PLWH) who undergo prolonged antiretroviral therapy (ART) may experience weight gain as a potential side effect. Many of these individuals are prescribed glucagon-like peptide 1 (GLP-1) receptor agonists (RAs), or dual GLP-1 and gluco...

Implementation barriers, facilitators, and fidelity of a mobile money-based savings tool for pregnant women in the Analamanga region of Madagascar: an ex-post process evaluation

Abstract Background Mobile payment services could improve access to obstetric care by easing saving, raising revenue, and pooling resources. Between 2019 and 2022, a mobile money-based savings tool for obstetric care was implemented in the Analamanga region of Madagascar followin...

Why change management initiatives fail during strategy implementation: a multi-level qualitative case study

Purpose This study aims to examine why change management initiatives fail during strategy implementation by analysing how failures emerge, interact and compound across organisational levels. Design/methodology/approach A qualitative single embedded case study was conducted within...

Cobalamin‐Dependent O ‐Demethylation of Polymethoxyflavones by Enzymes Isolated From the Human Gut Microorganism Blautia producta MRG‐PMF1

O ‐demethylation of aryl methyl ethers is an invaluable transformation, playing a critical role in ecological circulation by degrading abundant lignin‐derived compounds and other natural products. Chemical O ‐demethylation requires harsh reaction conditions; thus, the need for bi...

Unlocking business performance in logistics: the hidden power of software-enabled decision-making and process capabilities: evidence from Türkiye

Inderscience is a global company, a dynamic leading independent journal publisher disseminates the latest research across the broad fields of science, engineering and technology; management, public and business administration; environment, ecological economics and sustainable dev...

Fe3O4 Nanopowder under the Effectof Conventional Ultrasonication Treatment

Abstract A new study was conducted to assess the actual effect of ultrasonication, a highly common treatment used to desegregate and deagglomerate nanoparticles for their subsequent dispersion in different media. In particular, Fe3O4 conventional magnetite nanoparticles suspended...

Working from the inside out

Purpose This paper aims to review the latest management developments across the globe and pinpoint practical implications from cutting-edge research and case studies. Design/methodology/approach This briefing is prepared by an independent writer who adds their own impartial comme...

Sleep disturbances as early indicators of incident psychiatric disease

PURPOSE: Sleep disturbances are common in individuals with psychiatric diseases and may emerge years before diagnosis. It remains unclear whether they reflect modifiable risk factors or early manifestations of psychiatric illness. We aimed to investigate how different sleep dimen...