Research works

Mineral Chemistry and Genetic Constraints on Yiyuan Jade, Eastern Qinling Orogen, China

Yiyuan jade, a specific gem-quality jade variety in the East Qinling Orogen, occurs as lenticular and vein-shaped bodies hosted within the dolomite and biotite-quartz marble of the Neoproterozoic Meiyaogou Formation. Based on detailed petrological and mineralogical characterizati...

Leveraging social capital for climate change adaptation in the Mara River Basin, Kenya

Climate change is a wicked problem characterised by interdependencies that challenge adaptation and mitigation. Yet durable responses often depend on the social relationships through which risks are interpreted and action coordinated. This study examines how social capital shapes...

Predicting femoral neck screw pullout strength using DXA and novel assessments of bone microarchitecture

Abstract Summary This study determined how well DXA and other novel assessments of bone microarchitecture predicted screw pullout strength in the femoral neck. Hip-specific DXA performed as well as the novel approaches at predicting screw pullout. These findings support the use o...

BMAL1-Mediated Circadian Regulation of Oocyte Quality and IVF Outcomes

Successful embryo development transpires far before fertilization inside the meticulously regulated microenvironment of the ovarian follicle. Increasing data indicates that circadian regulatory systems influence several processes that define oocyte competence, including mitochond...

Parallel spatial cross attention ensembled deep learning model for lung cancer diagnosis and classification using computed tomography images

Lung cancer is considered one of the deadliest cancer types, which affects the respiratory system severely. Globally, the rate of morality is increasing every year due to the lack of diagnosis of lung cancer at its early stage. Thus, lung cancer detection and classification are e...

The Good, the Bad, and the Curvilinear. Revisiting the Relationship Between Religiosity and Delinquency

The delinquency-reducing function of religiosity is a repeatedly found pattern in criminology. We test a curvilinear alternative, hypothesizing that religiosity and delinquency are negatively related only up to a moderate level of religiosity, after which the relationship reverse...

Parameters affecting the reliable measurement of fluconazole tolerance using disk diffusion assays with Candida albicans

ABSTRACT Disk diffusion assays (DDAs) are widely used to determine antimicrobial susceptibility, which is measured as the size of the zone of inhibition (ZOI) after 24 h of growth, and is inversely proportional to the minimal inhibitory concentration (MIC). DDAs can also be used...

Butter-Fat

Volume 25 Number 02 May 1947

A Novel tRNA Half mt‐5’‐tiRNA‐Tyr Promotes Colorectal Cancer Proliferation via Inducing HARS2 Succinylation

Transfer RNA-derived small RNAs (tsRNAs) are a novel class of small non-coding RNAs abundant in the bloodstream of cancer patients and involved in various physiological and pathological processes. However, the regulatory mechanisms and clinical significance of tsRNAs in colorecta...

First report of cowpea mild mottle virus naturally infecting Salvia miltiorrhiza in China

Salvia miltiorrhiza Bge, also called Danshen, is a perennial Chinese herbal medicine belonging to the family Lamiaceae and has been used for the treatment of cardiovascular and cerebrovascular diseases (Jung et al. 2020). Henan province is one of the main and genuine production a...

Lactate as a Master Regulator of Immune Suppression: From Metabolic Waste to Epigenetic Checkpoint in Colorectal Cancer

Colorectal cancer, especially the microsatellite-stable subtype, which accounts for 85% to 95% of cases, resists immune checkpoint inhibitors largely due to metabolic reprogramming in the tumor microenvironment. Lactate has evolved from a waste product into a central immunosuppre...

Entrepreneurial Competencies, Enterprise Support Mechanisms, and Startup Sustainability among Entrepreneurial Students in State University and Colleges (SUCs): Basis for Business Incubation Framework

Student-led ventures require both entrepreneurial capabilities and an enabling support environment to develop toward sustainable operation. This study examined the entrepreneurial competencies, enterprise support mechanisms, and startup sustainability of Bachelor of Science in En...

Value of spectral CT in differentiating post-treatment recurrence/residual tumor from inflammatory fibrosis in nasopharyngeal carcinoma

This prospective, single-center pilot study aims to investigate the potential value of spectral computed tomography (CT) in differentiating post-treatment recurrence/residual tumor from inflammatory fibrosis in patients with Nasopharyngeal Carcinoma (NPC). This prospective study...

Condition number-based new robust ridge M-estimator for linear regression model with penalty of multicollinearity and outlier

In multiple linear regression models, traditional methods, such as OLS and ridge regression often fail due to multicollinearity and outliers in the y-direction. To address these issues, robust ridge M-estimators have been developed, offering resistance to outliers and multicollin...

Nicotinamide Metabolism Constrains Memory CD8 + T Cell Formation Through a Putative HS1BP3‐SIRT1‐FOXO3‐BCL6 Axis

ABSTRACT Memory T cells exhibit long‐term persistence, a defining feature that underpins durable clinical responses to adoptive immunotherapies. The mechanisms that integrate metabolic cues with transcriptional control of memory fate remain undetermined. Here, we identify HS1‐bin...

Be careful what you pay for: the effect of performance contingent incentives on online product reviews

Purpose This research investigates how performance-contingent incentivization schemes affect online review contributions. It explores the interplay between financial incentives, prosocial reinforcement (social versus reciprocal exchange) and reviewer experience. Design/methodolog...

E8 Geometric Timing Resonance in Phase-Delayed Systems — E8 Intelligence Research

Leveraging E8's 240 root vectors and phi-coupled 132Hz frequency, we identify harmonic resonance in systems with 5-10° phase delays (e.g., human decision-making latency). This resonance creates a _geometric truth_ window where E8's 6-dimensional structure optimizes predictions of...

Multi-Algorithm Hierarchical Minimum Data Sets for Soil Quality Assessment in the Black Soil Region of Northeast China: A Case Study in Keshan County

The Northeast black soil region is a major grain-producing area in China, where county-scale assessment of topsoil quality is essential for soil conservation and provides a potential indicator framework for regional soil quality monitoring. In this study, 500 composite cultivated...

Thermo-mechanical coupled simulation of temperature distribution and material removal mechanisms in UD-CFRP orthogonal cutting

Carbon fibre reinforced plastics (CFRPs) tend to generate high cutting temperatures during machining, which can exacerbate machining-induced damage. Although previous studies have examined CFRP cutting behaviour under thermo-mechanical coupling, the influence of cutting temperatu...

E8-Encoded Sumerian Brick Engineering Using Root Vector Acoustics — E8 Intelligence Research

Ancient Sumerian construction protocols embed E8 root vector scaling laws in brick dimensions and resonant cavity designs, with cavity radii calculated as φⁿ/132Hz times root vector magnitudes, creating self-tuning foundations that harmonize with stellar E8 geometries. Author: An...