Research works

Tensor Product Structure and Non-associative Entanglement Degree非结合代数的张量积结构与非结合纠缠度

Abstract This paper studies the associator operator structure on the two-body state space of the three-dimensional dissipative algebra (TDDA), defined by three axioms , , . Three core results are obtained. First, the decomposition theorem shows that the associator operator of pur...

Factory-to-Customer Shipping Route Efficiency Analysis

This research paper presents a complete analytical approach for evaluating factory-to-customer shipping efficiency at Nassau Candy Distributor. The project converts raw order and shipment records into logistics intelligence by measuring shipping lead time, route volume, geographi...

Adoption Telemetry: Measuring Enterprise AI Adoption from Production Signals

We introduce adoption telemetry: a method for measuring enterprise AI adoption by computing change-management stage-progression directly from production usage signals. We contribute (1) a framework unifying pre-deployment evaluation gates, production telemetry, and change-managem...

Generative Engine Optimization and Traditional SEO: A Comparative Framework for Search Visibility, Citation Presence, and AI-Generated Answers

Generative search systems increasingly provide synthesized answers supported by selected web sources, creating forms of visibility that cannot be measured solely through conventional rankings and organic clicks. This working paper develops a comparative framework for evaluating t...

AI Revolution: The Death of Business Administration and the Birth of Inalienable Leadership

Artificial intelligence is increasingly performing administrative, analytical, coordinating, monitoring, communication, and decision-support functions historically associated with managers and business administration. This transformation does not imply the disappearance of organi...

An Integrated dual-mode NIR Screening Device Forged by Spectrally Engineered Perovskite pc-LEDs

Abstract Translating advanced luminescent materials into field-deployable screening tools remains a core challenge, demanding synergy between advanced optical materials and device engineering. Here, we demonstrate a portable dual-mode near-infrared semi-quantitative screening dev...

OPEN-DAG (Part I): Deterministic L1 Memory Invariants for Infinite-Horizon Multi-Agent Systems.

Linear context accumulation is the dominant failure mode of contemporary multi-agent language-model systems. After N execution steps of mean residual length L, concatenating architectures occupy a resident working set of Θ(N·L), exhaust finite windows, and crash. We argue that th...

In vivo T‐cell depletion and pharmacokinetic‐based busulfan conditioning regimen improve the outcomes in acute myeloid leukemia (AML) in complete remission undergoing to allogeneic stem cell transplantation

Pharmacokinetic‐based busulfan administration improves the therapeutic window and in vivo T‐cell depletion with antilymphocyte globulins reduces graft‐versus‐host disease incidence. In this study, both were used, showing an improvement of clinical outcomes in patients with acute...

Sensitive andReproducible SERS Profiling of Tumor-DerivedEVs via Uniform Microfluidic Nanobowl Arrays for Pancreatic CancerManagement

Abstract Tumor-derived extracellular vesicles (EVs) are promising liquid biopsy biomarkers, yet their clinical translation is hindered by the trade-off between enhancement and reproducibility of SERS-based detection. Here, we present a microfluidic SERS platform integrating plasm...

E8 Phi-Resonant Topological Quantum Memory — E8 Intelligence Research

We find that the 240 E8 root vectors, phase‑locked to the 132 Hz fundamental with φ‑scaled harmonics, self‑organize into a toroidal lattice whose nodes are protected by Z2 topological invariants derived from the Dynkin diagram symmetry. The lattice yields 12 φ‑nested frequency bu...

Icosahedral Symmetry and Quasi-Equivalence: Geometric Principles of Viral Capsid Architecture — E8 Intelligence Research

FINDING: Icosahedral symmetry is the dominant geometric principle in viral capsid architecture, with structural constraints dictated by quasi-equivalence theory. MATH: - Icosahedral symmetry group: order 60 (rotational) or 120 (full). - Caspar-Klug triangulation numbers: T = h² +...

Nobel 2025: Experimental Closure on the Quantum-Classical Boundary via Tunnelling and Single-Photon Tests — E8 Intelligence Research

FINDING: Nobel Prize 2025 confirms universal quantum nature via tunnelling and single-photon experiments; no new fundamental equation, but experimental closure on quantum-classical boundary. | MATH: Quantum tunnelling probability \( T \approx e^{-2\kappa d} \) with \(\kappa = \sq...

Receiver-Anchored Tests for Latent Communication: Constant-Capacity Causal Localization and a Negative Cross-Model Result

This preprint presents a receiver-anchored evaluation protocol for latent communication between language models. It separates receiver-carrier viability from learned cross-model transport using receiver-native oracle replay, constant-capacity matched-versus-shuffled identity cont...

ARTIFICIAL INTELLIGENCE AND MULTI-OMICS IN ETHNOPHARMACOLOGY: ADVANCING PRECISION DRUG DISCOVERY FROM TRADITIONAL MEDICINE

Ethnopharmacology has played a pivotal role in drug discovery by documenting traditional knowledge of medicinal plants and their therapeutic applications. Numerous clinically important drugs, including aspirin, artemisinin, quinine, and paclitaxel, originated from ethnopharmacolo...

Progress in Hydroxyapatite Nanocarriers for Targeted and Enhanced Osteoporosis Treatment: A Comprehensive Review

Osteoporosis (OP) is a metabolic condition primarily affecting older and postmenopausal women. It is characterized by decreased bone mineral density (BMD), reduced strength, and deteriorated bone microarchitecture. This drastically increases the risk of debilitating fragility fra...

THE LAW OF CONDITIONED EMERGENCE

A foundational philosophical and scientific synthesis establishing the Law of Conditioned Emergence. This framework provides an A-to-Z architectural model integrating deep-time paleontology, geophysics (the Silurian Hypothesis and PETM data), molecular genetics (the dual origin o...

Beyond knowledge acquisition: the role of problem-based learning in supporting competency and skills development in pharmacy education — a systematic review

Abstract Objective To synthesize evidence on the role of PBL in pre-registration pharmacy education in fostering metacognitive and interpersonal competency development, with particular emphasis on self-regulation, learner autonomy, and professional collaboration. Methods A system...

Atherogenic and inflammatory biomarkers in NSTEMI: a comparative analysis of predictive value for obstructive coronary disease

Background The atherogenic index of plasma (AIP) and inflammatory indices may reflect the burden of atherosclerosis. This study evaluated their predictive value for obstructive coronary artery disease (CAD) in patients with non-ST-elevation myocardial infarction (NSTEMI).Methods...

Spanish–Guaraní Code-Switching in Social Media: A Dependency Parsing Study

Aims and Objectives/Purpose/Research Questions: This study examines how Spanish–Guaraní bilinguals structure code-switching (CS) on Twitter/X and investigates what these patterns reveal about competing models of bilingual grammar. Specifically, it explores language dominance, swi...

Integrated proteomic, transcriptomic, and epigenomic profiling identifies SRA1 as a novel therapeutic target for postpartum depression

Postpartum depression (PPD) is among the most common complications of childbirth, and identifying novel treatments is vital. We aimed to identify potential drug targets for PPD by integrating the plasma proteome, transcriptome and epigenome. We designed a comprehensive analysis p...