Research works
The research papers we track — the newest first. Works with a plain-language summary link to it.
76240 work(s)
- Biology
History of divergence and gene flow shaping geographic variation in Andean warblers (Myioborus).
Studying how genetic variation is structured across space, and how it relates to divergence in phenotypic traits relevant to reproductive isolation, is important for our understanding of the speciation process. We used ddRAD-seq data to examine genetic variation across the distri...
- BiologyOpen access
Abstract When organisms encounter pathogens, they rapidly activate complex defense programs to ensure survival. While these immune responses are vital, they often also incur trade-offs, such as reduced growth and development and must therefore be tightly controlled 1,2 . In this...
- BiologyOpen access
ABSTRACT Schizophrenia is associated with profound working memory deficits, for which there are no approved treatments. Rare heterozygous null mutations in SETD1A , a gene encoding a key epigenetic regulatory protein, have been definitively linked to increased risk for schizophre...
- BiologyOpen access
Insulin-Regulated Actin Dynamics is Disrupted in a Human Keratinocyte Model of Hailey Hailey Disease
Abstract Hailey Hailey Disease (HHD) is an autosomal dominant cutaneous disorder caused by mutations in ATP2C1 , the gene encoding the Golgi/secretory pathway Ca 2+ -ATPase SPCA1. Characterized by suprabasal acantholysis and intertriginous blistering of the skin, HHD treatment fo...
- Physics & SpaceOpen access
Wavelength Requirements for Life Detection via Reflected Light Spectroscopy of Rocky Exoplanets
Searching for signs of life is a primary goal of the Habitable Worlds Observatory (HWO). However, merely detecting oxygen, methane, or other widely discussed biosignatures is insufficient evidence for a biosphere. In parallel with biosignature detection, exoplanet life detection...
- Society & EconomicsOpen access
A framework for evidence-based psychotherapy with AI (EBP-AI).
Artificial intelligence (AI) systems and large language models (LLMs) offer substantial potential to augment or even fundamentally change elements of psychological assessment and treatment. However, current AI technologies have yet to demonstrate the capacity to effect meaningful...
- BiologyOpen access
Abstract Live cells in tissue are plastic, phenotypically dynamic, and modify their function in response to genetic and environmental perturbations. To unleash the power of live-cell imaging to identify phenotype-genotype-function coupling over time, we report the development of...
- Health & MedicineOpen access
Abstract Motivated by distinct walking patterns in real-world free-living gait data, this paper proposes an innovative curve-based sampling scheme for the analysis of functional data characterized by a mixture of covariance structures. Traditional approaches often fail to adequat...
- Physics & SpaceOpen access
Gaia’s Promise to Detect Compact-object Binaries: Where We Stand with the Third Data Release
Abstract With its third data release (DR3), Gaia begins unveiling dormant candidate compact object (CO) binaries with luminous companions (LC) as predicted by several past theoretical studies. To date, three black hole (BH), 21 neutron star (NS), and ≈3200 white dwarf (WD) candid...
- Engineering & TechnologyOpen access
<title>Abstract</title> This paper presents a cost–benefit analysis (CBA) of proposed high-capacity cycling corridors in the wider Ljubljana area, representing the first such evaluation in Slovenia, where comparable infrastructure has not yet been implemented. The low baseline cy...
- Society & EconomicsOpen access
Abstract Background With a large proportion of adults in Canada vaccinated against SARS-CoV-2, it is important to identify who remain at risk for severe COVID-19 outcomes after primary vaccination/additional (booster) doses. Methods Adults (≥18 years) who received at least a prim...
- Climate & EnvironmentOpen access
An interactive online health risk assessment has been created to visualize the health risks associated with climate change at the district level (NUTS3) across Germany. The tool provides a comprehensive assessment by depicting both the current risk patterns and projected conditio...
- Engineering & TechnologyOpen access
Optimal placement of viscous dampers is essential for enhancing the seismic performance of high-rise buildings. In this study, we propose a target-oriented krill herd algorithm with a dynamic search mechanism (DTOKH) to optimize the placement of viscous dampers in high-rise build...
- Society & EconomicsOpen access
Globalization and Market Power
ABSTRACT We use a large episode of trade liberalization in Spain to test a rich set of channels linking trade and markups. The effect of reductions in import tariffs on firm‐level and aggregate markups is pro‐competitive, but there are offsetting effects via other channels. We sh...
- BiologyOpen access
Integrated metabolomics data analysis to generate mechanistic hypotheses with MetaProViz
ABSTRACT With the growing number of metabolomics and lipidomics studies, robust strategies for bioinformatic analyses are increasingly important. However, the absence of standardized and reproducible workflows, coupled with ambiguous metabolite annotations, hampers effective anal...
- Climate & EnvironmentOpen access
Sobre as perspectivas teórico-metodológicas da Agroecologia
This paper is a detailed characterization of the process of participatory research that develops the Agroecology. In this process, a dynamic generation of reflexivity is created, through methods and techniques employed in three different phases. In the first one (Ecological and P...
- Climate & EnvironmentOpen access
This text seeks to reflect on the trajectory of social mobilization for the construction of the notion of coexistence with the semi-arid, from the decade of 1990. The coexistence of the human being with his environment is an essential dimension of Agroecology, having as perspecti...
- BiologyOpen access
The starting point of this paper is the unfeasibility situation of the industrialized agriculture model and the dominant agro-food regime. Building a sustainable alternative is urgently needed. In the last decades, a great number of agroecological experiences have emerged which c...
- Materials & EnergyOpen access
ABSTRACT Structural and optical characterization of Eu 3+ doped atomically precise bismuth oxido nanoclusters (BiO‐NCs) of about 2 nm in size is reported. The BiO‐NC [Bi 38 O 45 (NO 3 ) 24 (dmso) 28 ]:Eu ( C‐1 D :Eu ) is transformed into soluble methacrylate ( − OMc) coordinated...
- Engineering & TechnologyOpen access
<title>Abstract</title> Phosphorus (P) use in agriculture remains inefficient and poses long-term environmental concerns. We investigate the uptake, redistribution, and efficacy of foliar-applied nano-hydroxyapatite (nHAp) in P-deficient barley (Hordeum vulgare), aiming to clarif...