Research works

Domain-combination based pan-genomic tree of life

Abstract Reconstructing the Tree of Life (ToL) remains a central challenge in evolutionary biology. While sequence-based methods have resolved much of life’s diversity, deep evolutionary relationships often remain elusive, particularly across the three superkingdoms of life. Here...

The Nature of Turbulence at Subelectron Scales in the Solar Wind

Abstract The nature of turbulence at subelectron scales has remained an open question, central to understanding how electrons are heated in the solar wind. This is primarily because spacecraft measurements have been limited to magnetic field fluctuations alone. We resolve this by...

Second-order AAA algorithms for structured data-driven modeling

Abstract The data-driven modeling of dynamical systems has become an essential tool for the construction of accurate computational models from real-world data. In this process, the inherent differential structures underlying the considered physical phenomena are often neglected m...

Brief communication: Towards defining the worst-case breach scenarios and potential flood volumes for moraine-dammed lake outbursts

Abstract. Moraine dam failures are the main source of catastrophic glacial lake outburst floods (GLOFs). The effective GLOF disaster risk management requires reliable identification of areas at risk. While predictive outburst flood modelling benefits from advancing tools and comp...

Codimension two spacelike submanifolds into null hypersurfaces of generalized Robertson–Walker spacetimes

Abstract We study codimension two spacelike submanifolds contained into a general class of null hypersurfaces in generalized Robertson–Walker spacetimes, refer to as nullcones. In particular we analyze light cones and lightlike cylinders in Lorentz–Minkowski spacetime, as well as...

On the coming down from infinity of continuous-state branching processes with drift-interaction.

We study the phenomenon of coming down from infinity – that is, when the process starts from infinity and never returns to it – for continuous-state branching processes with generalized drift. We provide sufficient conditions on the drift term and the branching mechanism to ensur...

Effects of the ekpyrotic mechanism on inflationary phase in loop quantum cosmologies

Abstract In bouncing cosmological models – whether classical or quantum – the big bang singularity is replaced by a regular bounce. A well-known challenge is controlling the growth of shear during the contracting phase, as the shear scales as $$a^{-6}$$ a - 6 toward the bounce, w...

Active learning strategies for the estimation of a feasible set defined from a vector output black-box simulator

Many industrial problems require the use of black-box numerical simulators, for which it is essential to determine the set of so-called feasible input parameters. A set of parameters is feasible if the output of the code on these parameters satisfies given constraints, for exampl...

Waltz: Temperature-Aware Cooperative Compression for High-Performance Compression-Based CSDs

Data compression is widely adopted for modern solid-state drives (SSDs) to mitigate SSD lifetime issues. Researchers have proposed compression schemes at different system layers, including device-side solutions like CCSDs ( c ompression-based c omputational S SD s) and compressio...

Analytical study on the exposedness of potential positions for external human-machine interfaces

As we move towards a future of autonomous vehicles, questions regarding their method of communication have arisen. One of the common concerns is the placement of the signaling used to communicate with pedestrians and road users, but few works have been fully dedicated to the matt...

Universal bound on microwave dissipation in superconducting circuits

Improving the coherence of superconducting qubits is essential for advancing quantum technologies. While superconductors are theoretically perfect conductors, they consistently exhibit residual energy dissipation when driven by microwave currents, limiting coherence times. Here,...

Constant-Factor Algorithms for Revenue Management with Consecutive Stays

Constant-Factor Policies for Consecutive-Stay Bookings Railway operators and hotels must decide whether to accept bookings while preserving capacity for future customers. In “Constant-Factor Algorithms for Revenue Management with Consecutive Stays,” Hu and Wu study this challenge...

Feasibility of implementing collaborative decision skills training among veterans with psychosis: a qualitative study guided by the practical, robust implementation and sustainability model

Abstract Background Collaborative Decision Skills Training (CDST) is a promising group intervention for adults with serious mental illness (SMI) intended to increase collaborative decision-making (CDM) at the patient-clinician level. CDST previously underwent a systematic, commun...

SRF fusion oncogenes encode constitutively activated chimeric transcription factors in myoid soft tissue tumors

ABSTRACT SRF fusion genes drive the pathogenesis of muscle-related soft tissue tumors, including subsets of perivascular tumors, inflammatory myofibroblastic tumor, and rhabdomyosarcoma. SRF encodes Serum Response Factor, a well-characterized transcription factor that regulates m...

Does experience of emotional invalidation in childhood lead to growth – a qualitative enquiry using Interpretative phenomenological analysis

Abstract Background Severe abuse is not the only variant of unpleasant experiences in childhood. Childhood maltreatment in the form of emotional invalidation is potent in shaping future behaviors, both adaptive and maladaptive. Traumatic experiences in childhood are such occurren...

The familiness matrix: A configurational instrument to capture heterogeneity in family firm logics

Familiness is central to understanding both the distinctiveness and the heterogeneity of family firms. Prior research has developed important scales and conceptualizations of family influence, socioemotional goals, and familiness-related dynamics. However, the literature still la...

China’s dual circulation strategy and its impact on European industry: the case of the electric vehicle

Abstract In recent years, the Chinese economy has been hit by several shocks that have heightened the country’s economic security imperative. However, Beijing’s search for greater ‘self-reliance’ is not entirely new. China has often shifted its attention between domestic and glob...

Heterogeneous Treatment Effects in Panel Data: Insights into the Healthy Incentives Program

Problem definition: We study how adding new vendors to the Massachusetts Healthy Incentives Program (HIP), a food subsidy program, affects program utilization. This is an instance of a core problem in causal inference: estimating heterogeneous treatment effects (HTEs) using panel...

Feasibility and safety of seated virtual reality rehabilitation for chemotherapy-induced peripheral neuropathy

Abstract Chemotherapy-induced peripheral neuropathy (CIPN) causes sensory and motor impairments that can significantly reduce quality of life. Although rehabilitation has shown promise as a nonpharmacological intervention, standardized programs have yet to be established. Effecti...

Rare Variants May Influence Disease Risk and Clinical Features in Sporadic Late-Onset Chinese Parkinson’s Disease Patients

BackgroundThe heritability in Parkinson’s disease (PD) may be contributed by rare variants (RVs) in candidate genes. Currently there is limited genetic data on Chinese PD patients.ObjectiveWe aim to identify RVs in Chinese PD patients and investigate their relationships with risk...