Research works

Osteotomies around the knee are associated with low short‐term adverse event and reoperation rates: A 25‐year national Hospital Episode Statistics analysis in England

Abstract Purpose Osteotomy around the knee (OAK) is an established joint‐preserving procedure. We sought to use large‐scale registry data to examine the short‐term reoperation and adverse outcome rates after OAK. Methods Data on high tibial osteotomy (HTO) and distal femoral oste...

Nitric oxide and wound healing: an update.

Because of its gaseous qualities, nitric oxide (NO) may pass across membranes and has a relatively short half-life. The enzyme complex nitric oxide synthase (NOS) in humans is responsible for the production of NO. This complex is composed of three distinct homodimeric isoforms: (...

Circular-orbit dynamics and QPO constraints in static Einstein–scalar–Gauss–Bonnet black holes

Abstract Einstein–scalar–Gauss–Bonnet (EsGB) gravity provides a physically motivated framework for testing strong-field deviations from the Schwarzschild geometry through scalar hair. We study neutral-particle circular motion and high-frequency quasi-periodic oscillations (HF-QPO...

Integrated Control and Planning of Virtual Coupled Modular Pods for Energy-Efficient Railway Operation

Sustainable and demand-adaptive railway operation requires frameworks capable of aligning service capacity with time-varying demand while ensuring safe, operationally feasible, and energy-efficient service. This paper proposes an integrated control-and-planning framework for modu...

Development of a Cutting Machine for Hybrid Rice Male Parents in Narrow-Row Agriculture: Design, Simulation, and Validation

To address seed contamination, narrow-row mechanized cutting difficulties, and potential damage to maternal plants in muddy paddy fields during hybrid rice seed production, a walk-behind self-propelled hybrid rice male parent pulverizing and cutting machine was designed. The mach...

Prenatal Ultrasound Screening for Corpus Callosum Anomalies: A Narrative Review

Prenatal detection of agenesis of corpus callosum (CC) anomalies is a challenge. Although a correct diagnosis of anomalies of the CC requires direct examination of the CC in the mid-sagittal plane of the fetal brain, the international guidelines on mid-trimester morphology scan d...

Beyond Efficacy: Policy, Delivery, and Equity Determinants of Long-Acting Monoclonal Antibody Uptake for Infant RSV Prevention—A WAidid Consensus Document

Background: Long-acting monoclonal antibodies have become an important strategy for pre-venting respiratory syncytial virus (RSV) disease in infants. Nirsevimab is the first product for which substantial post-licensure implementation data are available, whereas real-world evidenc...

The Loophole That Cannot Close: Why No Bell Test Can Exclude Quantum-Geometry Dynamics

Bell's theorem excludes theories that are both local and realist. Loophole-free Bell tests close the experimental gap by ensuring the two measurement events are spacelike separated — a light-cone constraint that rules out any subluminal influence connecting them. This paper argue...

Combination Treatments for Myopia Progression in Children: A Narrative Review

Despite a growing range of effective monotherapies for childhood myopia control, a subset of children continues to show suboptimal control, prompting interest in combination therapy. This narrative mini-review summarises recent evidence on combining pharmacological, optical, and...

The price of not belonging: The impostor phenomenon’s social stratification and its nexus to perceived discrimination and workplace belonging

This study facilitates a sociological understanding of the impostor phenomenon, a trending topic in academia and beyond. It examines the social stratification of the impostor phenomenon, its relationship to perceived discrimination, and its relevance for workplace belonging. Usin...

Immunometabolic Plasticity in Sarcopenic Obesity: Toward a New Paradigm for Precision Immunonutrition

Despite decades of research, immunonutrition continues to generate heterogeneous and often contradictory clinical outcomes, suggesting that nutrients do not exert fixed immunological effects but rather interact with the biological context in which they operate. Sarcopenic obesity...

Defense Against Information Integrity Attacks in Federated IoT Systems Using Inertial Momentum-Aware IALM-RPCA

While Federated Learning offers a decentralized approach to model training, ensuring the integrity of the information from each IoT client remains a challenge. This work delves into the dynamics of Multi-Stage Federated Learning, its susceptibility to information integrity attack...

AutoEmulate: A PyTorch tool for end-to-end emulation workflows

Computational simulations lie at the heart of modern science and engineering, but they are often slow and computationally costly. A common solution is to use emulators: fast, cheap models trained to approximate the simulator. However, constructing these requires substantial exper...

An Apparent Conservation's Laws Inconsistency Associated With Mixed Added--Mass Coefficients

The examination whether the conservation laws are violated due to the added mass matrix provided here. This work points to inconsistency of the momentum and mass conservation which might also indicate issues with energy conservation in the added mass matrix. In doing so the autho...

Proton mechanical forces structure revisited: Insights from Patterson function analysis

This study applies Patterson function analysis to gravitational form factors to reconstruct the proton’s mechanical force distribution. The resulting density profile is strictly positive and sharply localized, with a half‑maximum radius of 0.109 fm that defines the proton’s compa...

THE β-COHERENT QUARTIC METAMATERIALS: VISCOUS REGULARIZATION, FROBENIUS FILTERING, AND EFFECTIVE METRIC

We prove global well-posedness, uniform hyperbolicity τcoh≈0.061 s, ℱ≥0.999669, Q=49.92 and H-convergence for the viscosity-regularized quartic system ρ(∂tv+v·∇v)−μΔv+∇p=βcut∇·(|∇Φ|²∇Φ)χδ, ∂tΦ+v·∇Φ−βcutΔ̂β(Φ)+γradΦ=−S′p(Φ)+J, Δ̂β(Φ)=−β∇·(|∇Φ|²∇Φ). Geometry Ωshape=Ωcav∪Ωthroat∪Ωti...

Hierarchical Three-Body Problem at High Eccentricities = Simple PendulumIV: Octupole for Librating Kozai-Lidov Cycles

Abstract We solve analytically the long-term octupole evolution of librating Kozai-Lidov cycles - those with a negative Kozai constant, in which the argument of pericenter librates - in the double-averaged restricted hierarchical three-body problem. Librating cycles reach extreme...

Interpretability Engine Optimization (IEO): The Missing Optimization Layer in AI Commerce

Commerce is increasingly mediated by machines. A machine may retrieve an offer it does not fully understand; it cannot reliably constrain, compare, recommend, or transact on that offer without sufficient interpretation. Existing optimization disciplines — SEO, AEO, GEO and relate...

Distinctive properties of the prion protein in the brain and retina in the amyloidosis associated with the PRNP F198S mutation

Abstract Prion protein (PrP) deposits in the form of diffuse and cored plaques occur in most gray matter areas of the brain of individuals affected by Gerstmann-Sträussler-Scheinker disease (GSS) associated with the F198S mutation in PRNP; however, the PrP deposits in the retina...

THE CHRONO-GEOMETRY OF THE β-MATERIAL: GLOBAL EXISTENCE, HYPERBOLICITY AND VISCOUS SATURATION FOR A CUTOFF QUARTIC OPERATOR

We study an incompressible MHD system coupled to a scalar field Φ through a degenerate fourth-order energy term F_β = (β/4)(∂μ Φ ∂^μ Φ)² χ_R with cutoff χ_R of order q=5. The operator Δ̂{β,R}(Φ) := -∇·( β |∇Φ|² ∇Φ χ_R ) is of p-Laplacian type with p=5. The single parameter β has...