Research works
The research papers we track — the newest first. Works with a plain-language summary link to it.
78103 work(s)
- Climate & EnvironmentOpen access
Existing state cadastral land valuation methodologies often focus exclusively on economic factors while ignoring geo-environmental hazards. This paper proposes a mechanism for incorporating seismic risk indicators and environmental degradation into the cadastral model to improve...
- Physics & SpaceOpen access
How much unitary symmetry does the Born exponent actually need? Within coordinate-additive probability rules—each outcome weighted by a function $g$ of its amplitude modulus—invariance under a single genuine two-coordinate mixer already forces the quadratic $g(x)=cx^2$ for every...
- BiologyOpen access
Transposable elements (TEs) account for nearly half of the human genome and shape chromatin organization, gene regulation, and genome evolution. However, their contributions to human physiology and disease remain incompletely understood. The most active elements in humans, LINE-1...
- Health & MedicineOpen access
One Landscape, Many Inputs: Cancer Prevention as Cofactor-and-Gene Route-Competition
A Hypothesis & Theory / Ideas & Speculation synthesis of one-carbon (folate) metabolism, gene–diet interaction, and cancer chemoprevention. It builds on established multistage-carcinogenesis and chemoprevention findings (including the documented harm signals of some supplement tr...
- Health & MedicineOpen access
Clinical Prediction Models (CPMs) compute an individual's risk of an outcome, given a set of predictors. Guidance states CPMs should be constructed using data sampled from the target population. However, researchers might have access to ancillary data sets from different time poi...
- AI & ComputingOpen access
Background. The main protease (MPro) of coronaviruses (CoVs) is an essential enzyme involved in viral replication and represents an attractive target for antiviral drug discovery. Based on the similar binding pocket residues within the MPro of different CoVs, the study aimed to i...
- Materials & EnergyOpen access
Thermal cycling–induced nitriding increases energy-storage density in titanate ferroelectric films
Enhancing dielectric energy-storage density ( U e ) requires maximizing the difference between maximum and remanent polarizations (Δ P ). Improving Δ P remains fundamentally challenging, as existing strategies rarely achieve simultaneous high maximum polarization and low remanent...
- Health & MedicineOpen access
Background: Models of trauma-related dissociation rely on two conflicting assumptions: dissociation as a single transdiagnostic severity continuum versus dissociative disorders as categorically distinct from PTSD. Neither has been tested at the level of symptom organization acros...
- Society & EconomicsOpen access
As securing parents’ participation in elementary school activities is not guaranteed, identifying the factors that encourage such cooperation is necessary. We examined how Japanese parents’ perceptions of parent-school-community cooperation (team orientation) and leadership relat...
- BiologyOpen access
Targeted ATAC-see (tATAC-see): A visual assay for target-specific chromatin profiling
We present targeted ATAC-see (tATAC-see), a visual genomics assay for site-specific chromatin profiling. By integrating the in situ visualization of ATAC-see with antibody-tethered tagmentation, tATAC-see captures chromatin states at defined protein-occupied domains with the simp...
- Physics & SpaceOpen access
Abstract About 15 years ago, a new type of extreme (with kinetic energies of $$\textrm{E}_k \sim 10^{47-49}$$ E k ∼ 10 47 - 49 erg) molecular outflows associated with very luminous ( $$\ge $$ ≥ $$10^5$$ 10 5 $$\textrm{L}_\odot $$ L ⊙ ) and massive ( $$10^3$$ 10 3 $$\textrm{M}_\od...
- BiologyOpen access
Towards density-optimal DNA storage with practical bijective coding
DNA storage is a promising solution to data explosion due to its high density and longevity. However, existing coding methods struggle to efficiently avoid error-prone sequences while retaining usable ones, leading to low density and high copy numbers. Here we show Siyuan Code, a...
- Materials & EnergyOpen access
A strong-coupling theory for polarizable symmetrically charged walls with counterions only
A pair of parallel polarizable planar walls at a distance d is considered. The walls are symmetrically charged with a uniform surface charge density, neutralized by mobile point counterions moving between them. The case of repulsive particle images is studied in the strong-coupli...
- BiologyOpen access
Draining the Brain: A Novel Noninvasive Lymphatic Therapy for Parkinson’s Disease
The discovery of the glymphatic system and meningeal lymphatic vessels established that the brain possesses an organized lymphatic clearance network that drains to the deep cervical lymphatics. Disruption of this system has been suggested to contribute to the accumulation of path...
- Health & MedicineOpen access
Energetic cost of weight shifting and asymmetric weight-bearing during standing in humans
During prolonged standing, humans commonly shift their weight and spontaneously alternate between symmetric and highly asymmetric standing, bearing most of their body weight on one leg. Here, we tested the hypothesis that humans adopt asymmetric weight-bearing to reduce metabolic...
- BiologyOpen access
APLNR is a therapeutically important G protein-coupled receptor (GPCR) implicated in cardiovascular and metabolic regulation; however, how agonist binding reorganizes receptor dynamics to promote signaling competence remains poorly understood. Here, we used the small-molecule ago...
- Health & MedicineOpen access
Background/Objectives: The development of functional staple foods with improved metabolic properties represents a practical dietary strategy for the prevention of type 2 diabetes. This study investigated the effects of incorporating sprouted fenugreek (Trigonella foenum-graecum L...
- Society & EconomicsOpen access
Lexical Context Effects During Reading: The Impact of Vocabulary Knowledge and Word Frequency
Skilled readers are thought to rely on bottom-up processing to activate word meanings in long-term memory from their form (i.e., spelling or sound) in a process described as ‘context-free’ lexical processing. However, other research suggests skilled readers recognize words faster...
- Society & EconomicsOpen access
Sustainable refurbishment of historic healthcare complexes requires more than the preservation of isolated material fragments. It must reconcile cultural significance, continuity of care, inherited environmental qualities, contemporary technical requirements, material compatibili...
- Health & MedicineOpen access
Abstract Prognostic models for metastatic urothelial carcinoma (mUC) have limited accuracy and additional clinically meaningful factors are needed to improve risk stratification. Time to metastasis from initial diagnosis (TTM) is an established prognostic variable in other urolog...