Research works

The Evolving Role of Forensic Engineers in Construction Risk Management

Forum papers are thought-provoking opinion pieces or essays founded in fact, sometimes containing speculation, on a civil engineering topic of general interest and relevance to the readership of the journal. The views expressed in this Forum article do not necessarily reflect the...

The Apex Anchor Method: Extended Universal Framework & Mathematical Analysis (v13 Academic Edition)

This paper introduces The Apex Anchor Method (v13), a dynamic heuristic framework designed for rapidly accelerating non-linear functions. It features two operational modes: a Wide-Boundary Exploration Mode and a Localized High-Precision Engine operating within 1° proximity. Evalu...

Prognostic factors after pulmonary metastasectomy for colorectal cancer lung metastasis

Objective: Surgical resection of lung metastases in patients with colorectal cancer (CRC) can provide long-term survival in selected cases. This study aimed to evaluate the prognostic factors affecting survival after pulmonary metastasectomy (PM) performed for lung metastases due...

Lactylation-related immune-metabolic dysregulation defines prognostic and therapeutic stratification in lung adenocarcinoma

Background Lactylation links lactate metabolism with inflammatory signaling and immune regulation in tumors. However, its cellular distribution and translational value in lung adenocarcinoma (LUAD) remain unclear. Methods Single-cell RNA-sequencing datasets GSE189357 and GSE17114...

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Volume 34 Number 07 October 1956

HIV and STI Co-infection and Migration-Related Social Vulnerability among Venezuelan Gay and Bisexual Migrants in Lima, Peru

BACKGROUND: This study examined HIV, bacterial STI co-infection, and migration-related vulnerability among Venezuelan gay, bisexual, and other men who have sex with men (GBM) in Lima, Peru. METHODS: A total of 306 Venezuelan GBM of any serostatus living in Lima, Peru, were recrui...

Human Encryption System (HES): A Cognitive-Geometric Authentication and Cryptographic Primitive Leveraging Set Theory and Spatial Chess-State Reachability

This paper introduces the Human Encryption System (HES), a novel cryptographic and authentication framework that bridges abstract set theory, 3D affine spatial geometry, and combinatorial game-state reachability (chess). By mapping categorical piece sets to an 8x8 spatial grid vi...

Auxin-Transport PDE Reveals Phyllotaxis Spirals Without Ad Hoc Parameters — E8 Intelligence Research

FINDING: Phyllotaxis emerges from a pushed pattern-forming front in an auxin-transport PDE, yielding all observed spiral families without ad hoc parameters. | MATH: Golden angle θ = 137.51° = 2π(1 − 1/φ) where φ = (1+√5)/2 ≈ 1.618; divergence angle limit = 2π/φ² ≈ 137.5077°; Fibo...

Effect of live yeasts and essential oils as functional feed additives on growth performance and stress response in juvenile cobia

The intensification of aquaculture introduces significant challenges, including increased exposure to environmental stressors that promote disease outbreaks, historically managed through antimicrobial use. As sustainable alternatives, functional feed additives are being explored...

Chern-Simons Theory: Topological Invariants and the Gauge Structure of Spacetime — E8 Intelligence Research

FINDING: Chern-Simons theory is a topological quantum field theory where the action is metric-independent, yielding knot/link invariants via Wilson loops; its 3D gravity connection reveals a deep gauge-theoretic structure of spacetime. MATH: - Chern-Simons action: \( S_{CS} = \fr...

Association between thymidine kinase 1 and clinicopathological high-risk features in breast cancer

Thymidine kinase 1 (TK1) is a cell-cycle-regulated enzyme involved in DNA synthesis and is closely linked to tumor cell proliferation. This study investigated whether serum TK1 concentration is associated with clinicopathological high-risk features in breast cancer (BC) and wheth...

Coordination Costs and Homelessness Housing Form Choice

ABSTRACT Local implementers have discretion in selecting forms of housing for the homeless, yet the determinants of these choices remain poorly understood. Using the institutional collective action (ICA) framework, this study examines California's Homekey program to assess how co...

Risk factors for sudden cardiac death in heart failure

Background: Heart failure (HF) is a global health burden with high mortality. Sudden cardiac death (SCD) remains a major complication, highlighting the need for accurate risk prediction. Methods: We conducted a systematic review and meta-analysis, guided by the Population, Interv...

Biogeoclimatic Regions and Land-Use Structure Bacterial Biodiversity and Inferred Nitrogen-Cycling Potential in Headwater Stream Sediments

Abstract Microbial communities in freshwater ecosystems are structured by both natural environmental variation and anthropogenic pressures, yet how these drivers interact to shape biodiversity and ecosystem functioning remains poorly understood. Here, we assessed how biogeoclimat...

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Volume 40 Number 01 April 1962

INADVERT-CX Reproducibility Archive: search, deduplication, and dual-review screening record for a systematic review and meta-analysis of completion surgery after simple hysterectomy for occult cervical cancer

This archive provides the complete post-export reproducibility record for the study-identification and screening phases of the systematic review and meta-analysis "Residual Parametrial Involvement and Pelvic Nodal Metastasis at Completion Surgery for Cervical Cancer Diagnosed Fol...

Targeting Inflammation in CKD-Related Anemia: The Emerging Role of Lactoferrin as an Adjunctive Therapy

Objective: Chronic kidney disease (CKD)-associated anemia is substantially driven by chronic inflammation, which promotes hepcidin upregulation, restricts iron availability, and impairs erythropoiesis. Conventional therapies, including erythropoiesis-stimulating agents and iron s...

Early‐Life Telomere Length Negatively Covaries With Brood Size and Father Age, and Predicts Long‐Term Survival in Male Barn Swallows ( Hirundo rustica )

Parental decisions on breeding, such as brood size and timing of reproduction, influence the early-life environment of the offspring, exposing them to variable levels of stressors, which in turn may affect their fitness. In this context, telomeres, conserved DNA sequences at chro...

Mapping the fragmented landscape of privacy in the age of generative AI: a bibliometric analysis and future research agenda

Purpose This study aims to examine the evolution of privacy research in artificial intelligence (AI) and generative artificial intelligence (GenAI).This study investigates how privacy has been conceptualized across technical, organizational, behavioral, ethical and governance per...

Constructive Organizational Geometry: From Configuration Structure to Transport, Connection, and Curvature

This paper develops the geometric layer of the Organizational Field Theory research program by examining how admissible organizational configurations can acquire a mathematically consistent geometric realization. Beginning with an organizational quotient rather than a preselected...