Research works

Healthy subjects gut microbiome modulation by Bacillus coagulans BCP92

Background: Probiotics are recognized for their ability to restore balance in the gut microbiome during dysbiosis. However, their effects on the gut microbiota of healthy individuals have rarely been investigated. This study aimed to evaluate the safety and efficacy of Bacillus c...

Uncertainty-aware multi-objective optimization for rebalancing bike shared systems

Abstract Overnight rebalancing in dock-based bike-sharing systems requires routing a limited fleet of trucks before user activity begins. This article formulates static rebalancing problem under stochastic demand uncertainty as a bi-objective combinatorial optimization problem th...

The Windmill Problem: A Rotational Symmetry Masterpiece in IMO History — E8 Intelligence Research

FINDING: The 2011 IMO "windmill" problem (Q2) is the standout mathematical artifact — it encodes a rotational symmetry argument about finite point sets, while the 2026 IMO Problem 1 and the "hardest ever" problem are pedagogical showcases of combinatorial and number-theoretic ext...

Macroscopic Quantum Teleportation: Progress Without a Unified Mathematical Law — E8 Intelligence Research

FINDING: Macroscopic quantum state transfer is advancing via atom interferometry, macroscopic tunneling, and entangled mechanical-object tomography — but no unified mathematical law for teleportation of macroscopic objects emerges from these sources. | MATH: No explicit equations...

Genome-Wide Analysis of Alternative Splicing Identifies a Prognostic Signature in ER-Positive Breast Cancer

Background/Objectives: Alternative splicing (AS) contributes substantially to transcriptomic diversity and has emerged as an important regulator of cancer progression. However, the genome-wide characterization of AS events specific to estrogen receptor (ER)-positive breast cancer...

Sartorial Armor and Systemic Violence: A Socio-Psychological Analysis of Criminal Legitimacy, Brand Contamination Immunity, and the Industrialization of Human Vulnerability

This paper conceptualizes the "Sartorial Armor Paradigm," examining the socio-cultural mechanisms bywhich formal tailoring resists brand contamination while commercial luxury labels frequently succumbto subcultural degradation. By analyzing organized crime’s historical reliance o...

Optical signatures and functional insights of E-C-C-Ce bio-nanocomposite

In the present study, a novel and flexible eco-friendly E-C-C-Ce (ethyl cellulose-chitosan-carbon black-CeO 2 ) bio-nanocomposite film has been developed via a simple solution-casting route. The work focuses on understanding the influence of CB/CeO 2 nanofillers on the optical, d...

Butter-Fat

Volume 40 Number 03 August 1962

Kraft-McMillan Inequality as Discrete Sphere Packing via Root Systems — E8 Intelligence Research

FINDING: Kraft-McMillan inequality defines the exact boundary condition for uniquely decodable codes, linking discrete information theory to lattice geometry via root systems. | MATH: Kraft-McMillan: ∑ 2^(−lᵢ) ≤ 1 (binary case); general: ∑ D^(−lᵢ) ≤ 1 for D-ary codes. E8 root sys...

A little sedge goes a long way : emergent vegetation as a key driver of littoral methane flux

In northern (>50°N) freshwater ecosystems, aquatic vegetation is expanding, potentially enhancing methane (CH₄) emissions through plant-mediated transport and organic matter input. Despite this, most studies do not directly measure CH₄ flux from shoreline emergent vegetation. To...

Red-Teaming the Honest Negatives: Bounded Closing Paths for a Compact Spherical-Tokamak Breeder and a Deuterium-Helium-3 Tandem-Mirror Burner

A reduced-order red-team of the binding gates of a compact spherical-tokamak breeder and a deuterium-helium-3 tandem-mirror burner. For each honest negative, alternatives are brainstormed, bounded, ranked, and only the promising ones promoted to high-fidelity validation. The curr...

A CLINICAL CASE OF ANKYLOSING SPONDYLITIS IN A PATIENT WITH DYSPLASTIC SCOLIOSIS

Damage to the musculoskeletal system is one of the most common manifestations of rheumatic diseases. However, the reason for its involvement in the pathological process may be other diseases or their combinations. Ankylosing spondylitis (AS) is one of the most difficult to diagno...

Hereditary Diffuse Gastric Cancer With Poorly Differentiated Gallbladder Adenocarcinoma: A Case Report Suggesting Carcinogenesis in the Stomach and Gallbladder Caused by a Pathogenic Germline Variant in CDH1

Background/Aim: Hereditary diffuse gastric cancer (HDGC) is an autosomal dominant cancer syndrome primarily characterized by a high lifetime risk of diffuse gastric cancer and lobular breast cancer. It is predominantly caused by inactivating germline variants in the tumor suppres...

Influence of salt concentration in the drying Lake Urmia on the saltwater intrusion

Study region Lake Urmia and its adjacent coastal aquifer in northwestern Iran, a region that has experienced substantial lake shrinkage over recent decades. Study focus Lake desiccation has increased salinity and water density while lowering lake levels, introducing competing con...

Thermal-Barrier Decoupling - The Cornerstone Plug Mechanism

The plug's electrostatic potential is the burner's binding gate. A thermal barrier — a local density/potential depression sustained by ECH hot electrons and sloshing ions — decouples the plug potential from the central-cell electrons: the ion-confining-potential requirement drops...

Higher holonomy for curved L∞-algebras 1: simplicial methods

We construct a natural morphism ρ from the nerve MC∙⁡(L)=MC⁡(Ω∙⊗^L) of a pronilpotent curved L∞-algebra L to the simplicial subset γ∙(L)=MC⁡(Ω∙⊗^L,s∙) of Maurer-Cartan element satisfying the Dupont gauge condition. This morphism equals the identity on the image of the inclusion γ...

Rosacea epidemiology: a meta-analysis

Background. Rosacea is a chronic, multifactorial dermatosis, the epidemiology of which is a pressing issue in modern dermatovenereology. Objective. To analyze the incidence of rosacea in the Republic of Bashkortostan for 2019—2023, as well as to review literature data on the prev...

Sikh immigration, theology, and pan-ethnic solidarity: A comparative analysis of Sikh theology practiced in three different nation-states

This paper examines how Sikh theological principles, specifically Miri-Piri (the unity of spiritual and temporal authority) and Sarbat da Bhala (welfare of all humanity), function as operational frameworks for political action and pan-ethnic solidarity across the global Sikh dias...

LLM-Assisted Initial Population Generation for Multi-Objective Joint Service Placement and Traffic Routing in 6G Networks

In forthcoming 6G networks beyond 5G, services with increasingly stringent performance requirements are expected to emerge, requiring dynamic and flexible service placement and traffic routing. Furthermore, the integration of non-terrestrial networks for global coverage introduce...

Butter-Fat

Volume 36 Number 10 January 1959