Research works

ASSESSMENT OF KNOWLEDGE, ATTITUDE, AND PRACTICE OF EMERGENCY CONTRACEPTION AMONG FEMALE STUDENTS OF FEDERAL COLLEGE OF EDUCATION (TECHNICAL), GOMBE, NIGERIA

Background: Emergency contraception (EC) is an important option for preventing unintended pregnancies. Despite its proven effectiveness, awareness, knowledge, and actual use among young women in Nigeria remain suboptimal. This study evaluated the knowledge, attitudes, and practic...

DESIGN, DEVELOPMENT, AND EVALUATION OF A POLYHERBAL FORMULATION FOR THE MANAGEMENT OF METABOLIC SYNDROME

Metabolic syndrome (MetS) represents a clustering of interconnected risk factors including central obesity, insulin resistance, dyslipidemia, and hypertension, which collectively increase the risk of type 2 diabetes mellitus and cardiovascular disease. The limitations of conventi...

ASSESSMENT OF SERUM ELECTROLYTES, UREA AND CREATININE IN A COMPARATIVE STUDY OF SOME HYPOGLYCEMIC DRUGS ON STREPTOZOTOCIN INDUCED ALBINO WISTAR RATS

Type 2 diabetes mellitus is the 7th leading cause of death in United States of America. One way by which this disease can be managed is through the use of hypoglycemic drugs. This study aims to investigate the effects of some hypoglycemic drugs such as Biguanide (metforming), sul...

A RETROSPECTIVE STUDY ON RISK FACTORS, LIFESTYLE MODIFICATIONS, PHARMACOLOGICAL PROFILE AND ASSOCIATED CO-MORBIDITIES IN WOMENS WITH POLYCYSTIC OVARIAN SYNDROME

Polycystic ovary syndrome (PCOS) is a common hormonal disorder in women of reproductive age characterized by irregular periods, hormonal imbalance, and polycystic ovaries. Retrospective findings show that obesity, central fat accumulation, physical inactivity, unhealthy diet, chr...

RARE CASE OF LIVER ABSCESS SECONDARY TO INTRAHEPATIC RUPTURE OF GALLBLADDER & CHOLECYSTOHEPATIC FISTULA COMPLICATING ACUTE CALCULOUS CHOLECYSTITIS IN AN UNCONTROLLED TYPE 2 DIABETIC: A CASE REPORT AND REVIEW OF LITERATURE

Acute calculous cholecystitis rarely progresses to intrahepatic perforation with formation of a giant liver abscess. Such cases are associated with delayed presentation, uncontrolled diabetes mellitus, and significant morbidity. We report the case of a 62-year-old male with poorl...

A MULTIMODAL AYURVEDIC TREATMENT APPROACH FOR AMAVATA (RHEUMATOID ARTHRITIS): A CASE REPORT

Amavata is a systemic inflammatory joint disorder characterized by the pathological association of Ama and Vata and shares several clinical features with rheumatoid arthritis (RA). This case report describes the clinical and serological outcomes of a sequential Ayurvedic Shodhana...

ROLE OF MEDICINAL PLANTS IN DIABETES MANAGEMENTS

Diabetes mellitus is one of the fastest growing metabolic disorders in the world today, and India carries one of the largest shares of this burden. Although insulin and oral hypoglycaemic drugs are widely used to manage blood glucose, many patients still experience poor glycaemic...

MANAGEMENT OF ABHYANTAR ARSHA (SECOND-DEGREE INTERNAL HAEMORRHOIDS) VIA TARGETED VASA PRATISARNIYA KSHARA KARMA AND COMPLEMENTARY ORAL REMEDIES: A CARE-COMPLIANT CLINICAL CASE REPORT

Background: Arsha (haemorrhoids) is a prevalent anorectal disorder classified under the Ashtamahagada (eight dreadful diseases) in Ayurveda due to its deep-seated pathogenesis and challenging prognosis. Modern lifestyle shifts, characterized by low-fibre dietary habits and prolon...

SYNTHESIS, SPECTRAL CHARACTERIZATION AND IN VITRO ANTIMALARIAL EVALUATION OF NOVEL QUINOLINE-BASED THIAZOLIDIN-4-ONE DERIVATIVES

A series of novel quinoline-based thiazolidin-4-one derivatives were synthesized through a three-step synthetic pathway involving nucleophilic substitution, Schiff base formation and cyclization reactions. Initially, 4-chloroquinoline was converted into 4-hydrazinylquinoline by r...

KARNA SRAV (OTORRHEA): AN INTEGRATIVE AYURVEDIC AND MODERN PERSPECTIVE

Karna Srav, described under Karna Roga in Ayurveda, refers to abnormal ear discharge and is considered a symptom rather than an independent disease.[12] It closely correlates with Otorrhea in modern medicine, commonly caused by infection, trauma, or tympanic membrane perforation....

PHYTOCHEMICAL, ANTIMICROBIAL ANALYSIS AND ANTIOXIDANT ACTIVITY OF CLITORIA TERNATEA LEAVES (APRAJITA)

This study is about a beautiful blue flowering plant called Clitoria ternatea, commonly known as ‘Aprajita’ in India and globally as the butterfly pea, blue pea, or Asian pigeonwings belonging to the family “Fabaceae”. This plant has been used in traditional ayurvedic medicine as...

A REVIEW OF UPAVANAVINODA: INSIGHTS INTO VRIKSHAYURVEDA FOR SUSTAINABLE AGRICULTURE AND ENVIRONMENTAL HEALTH

The domestication and cultivation of plants have been integral to human civilization since ancient times. In Ayurveda, Vrikshayurveda represents the traditional science of plant health and sustainable cultivation. Among its classical texts, Sharangadhara Paddhati (13th century CE...

IMPROVEMENT IN SEMEN PARAMETERS IN MEN WITH NON-OBSTRUCTIVE AZOOSPERMIA FOLLOWING INDIVIDUALIZED AYURVEDIC FERTILITY MANAGEMENT: A RETROSPECTIVE CASE SERIES

Background: Male factor infertility contributes to approximately 40–50% of infertility cases worldwide, with non-obstructive azoospermia representing one of the most challenging causes. Although assisted reproductive techniques remain the standard treatment, many couples seek con...

ECO-ANALYTICAL INNOVATION IN RP-HPLC: A SUSTAINABLE FRAMEWORK FOR METHOD DEVELOPMENT AND VALIDATION

Reverse Phase High-Performance Liquid Chromatography (RP-HPLC) is one of the most widely used analytical techniques in pharmaceutical analysis for the qualitative and quantitative determination of drugs. However, conventional RP-HPLC methods often require large volumes of organic...

PHARMACOVIGILANCE AND ADVERSE DRUGS REACTION

Pharmacovigilance, a scientific discipline of the public health and medicine. The primary goal is the detection, evaluation, understanding and prevention of ADRs and other drug-related problems. ADRs are a significant cause of patient morbidity and mortality, prolongs hospitaliza...

GREEN PHARMACY: ECO-FRIENDLY APPROACHES IN PHARMACEUTICAL MANUFACTURING – A REVIEW

Green pharmacy is an emerging approach that integrates the principles of environmental sustainability into pharmaceutical research, manufacturing, distribution, use, and disposal of medicines. The pharmaceutical industry contributes significantly to environmental pollution throug...

ASSOCIATION OF ANTIBIOTIC RESISTANCES AMONG MYCOBACTERIUM TUBERCULOSIS AMONG SALAH-ALDEEN COMMUNITY

Background: Mycobacterium tuberculosis, the etiological agent causing tuberculosis, is one of the most common contagious diseases that poses a serious threat to human health. As per the recent WHO report, TB incidence throughout the world amounts to 10.7 million and the total dea...

SUCCESSFUL GLYCEMIC CONTROL WITH MICON GOLD FACILITATING GRADUAL TAPERING OF ORAL HYPOGLYCEMIC AGENT - A CASE REPORT

Madhumeha is described under Prameha in Ayurveda and resembles Type 2 Diabetes Mellitus. Long-term hyperglycemia leads to microvascular and macrovascular complications. Ayurvedic formulations such as Vasant Kusumakar Rasa have been traditionally used in the management of Madhumeh...

MACHINE LEARNING IN PHARMACEUTICAL FORMULATION DEVELOPMENT

The use of ML algorithms in pharmaceutical research has enabled remarkable progress, especially by circumventing the problems inherent in the trial and error method of drug development. This review is intended to highlight the growing use of machine learning algorithms such as ar...

DEVELOPMENT OF HPMC-BASED MATRIX TABLETS FOR THE SUSTAINED RELEASE OF METFORMIN HYDROCHLORIDE

537 million individuals globally are affected by type 2 diabetes mellitus (T2DM) India has the highest number of cancer cases worldwide. Metformin Hydrochloride is classified as a biguanide of BCS Class III. It is the first oral agent used to treat diabetes. Side-effects of this...