Research works

CONCEPT OF SIRA IN SUSHRUTA SAMHITA: A REVIEW WITH MODERN ANATOMICAL CORRELATION

The Sushruta Samhita, one of the Brihattrayi (the three principal classical texts of Ayurveda), is regarded as the foremost authority on surgical science and is especially renowned for its detailed exposition of Sharira (Śārire Suśrutaḥ Śreṣṭhaḥ). It provides a comprehensive desc...

IMPACT OF HEADPHONES AND IN-EARBUDS ON HEARING PERCEPTION AND KARNANADA (TINNITUS) AMONG YOUNG ADULTS: AN OBSERVATIONAL CROSS-SECTIONAL STUDY

Background: The widespread adoption of personal audio devices (PADs), particularly headphones and in-earbuds, has increased the risk of recreational noise-induced hearing loss (NIHL) and tinnitus among young adults. Ayurveda describes similar auditory manifestations under Karnana...

CUSHING'S DISEASE IN A YOUNG ADULT WITH ADRENAL INCIDENTALOMA: A DIAGNOSTIC ODYSSEY THROUGH BIOCHEMICAL AND RADIOLOGICAL WORKUP

Cushing’s disease, resulting from ACTH-dependent hypercortisolism driven by a pituitary corticotroph adenoma, represents a diagnostically challenging endocrine disorder. We report the case of a 29-year-old male who presented with dyspnea and was found to have features of cortisol...

EVALUATION OF SAFETY AND EFFICACY OF ERASAVIR NASAL AND MOUTH SPRAY COMBINATION IN UPPER RESPIRATORY VIRAL INFECTIONS: A PROSPECTIVE RANDOMIZED CONTROLLED STUDY

ErasaVir, an investigational antiviral formulation developed by Strassenburg Pharmaceuticals Pvt. Ltd., is designed as a dual-application mouth and nasal spray intended to inhibit viral replication and prevent viral adhesion in the upper respiratory tract. Comprising natural oil...

A CLINICAL STUDY TO EVALUATE THE EFFICACY OF ERANDADI TAILA KARNAPOORNA ALONG WITH GOGHRITPANA IN THE MANAGEMENT OF KARNA BADHIRYA (SENSORINEURAL HEARING LOSS)

Shira is the part of the body where life along with sense faculties resides. There are five Gyanendriyan (Shira sense organs) mentioned by our Acharyas. Among them, the functional aspect of hearing is “Shravanendriya”. The seat of Shravanendriya is Karna..Hearing is an important...

RARE MEDICINAL PLANT HUGONIA BELLI SEDGW. PHYTOCHEMICAL PROFILING AND IN VITRO ANTIMICROBIAL PROPERTIES OF THE METHANOLIC LEAF EXTRACT

Hugonia belli, popularly known as Modira kanni gida, is a rare plant species in India. The main objective of this study was to examine the phytochemical constituents and in vitro antimicrobial activity of this plant. Qualitative screening revealed the presence of phenols, alkaloi...

A TYPICAL VIRAL PNEUMONIA MASQUERADING AS A TROPICAL ILLNESS

We present a case of a 1 4-year-old female from Mumbai who was referred to Tirunelveli Medical College and Hospital (TVMCH) with a 1 4-day history of high-grade intermittent fever, followed by progressive breathlessness and non-productive cough. Initial investigations revealed th...

UNANI PERSPECTIVE OF PEDIATRIC TUBERCULOSIS (SIL): CLASSICAL MANAGEMENT AND SUPPORTIVE STRATEGIES FOR ATT-INDUCED ADVERSE EFFECTS

Mycobacterium tuberculosis, the cause of tuberculosis (TB), continues to be a serious worldwide health concern, especially for children in high-burden nations. Due to its paucibacillary origin, ambiguous clinical presentation, and challenges with microbiological confirmation, pae...

REVIEW ON FORMULATION AND EVALUATION FOR ETHOSOMAL GEL

Ethosomal gel is an advanced lipid-based vesicular system developed to improve the topical and transdermal delivery of drugs by enhancing their penetration through the stratum corneum. Ethosomes are composed mainly of phospholipids, ethanol, and water, with ethanol playing a key...

PLASMID PROFILING AND POST-CURING ANTIBIOTIC SUSCEPTIBILITY EVALUATION OF SELECTED MULTIDRUG-RESISTANT SURGICAL SITE INFECTION BACTERIAL ISOLATES

Background: Multidrug-resistant (MDR) bacterial pathogens associated with surgical site infections (SSIs) represent a major therapeutic challenge due to widespread dissemination of plasmid-mediated antimicrobial resistance. Characterizing plasmid profiles and determining the cont...

THE HISTOLOGICAL AND BIOCHEMICAL EFFECTS OF THE N-HEXANE FRACTION OF TELFAIRIA OCCIDENTALIS LEAVES ON THE LIVER OF STREPTOZOTOCIN-INDUCED DIABETIC WISTAR RATS

Introduction: DM is a metabolic disorder that not only impairs pancreatic function but also disrupts liver protein balance and compromises hepatic structural integrity. Aim: To assess the effect of the n-hexane fractions of TO (nHFTO) leaves extracts on liver injury caused by DM....

A TYPICAL VIRAL PNEUMONIA MASQUERADING AS A TROPICAL ILLNESS

We present a case of a 1 4-year-old female from Mumbai who was referred to Tirunelveli Medical College and Hospital (TVMCH) with a 1 4-day history of high-grade intermittent fever, followed by progressive breathlessness and non-productive cough. Initial investigations revealed th...

PHYTOCHEMICAL SCREENING AND ANTIOXIDANT EVALUATION OF LANTANA CAMARA FLOWER EXTRACTS

Lantana camara, popularly called as Spanish flag and wild sage, belonging to the family Verbenaceae, is majorly distributed across India, notably in Jammu and Kashmir, South India, Himachal Pradesh, Uttar Pradesh, Maharashtra, and several other regions. Lantana camara is most wid...

SCOPE OF AGADATANTRA IN ENVIRONMENTAL POLLUTION WITH SPECIAL REFERENCE TO JANAPADODHWANSA

The escalation of global industrialization has made environmental degradation a primary driver of both acute and chronic human pathologies. Modern public health systems struggle to contain the multi-systemic impact of chemical, atmospheric, and aquatic toxins. This review examine...

FRUITS OF ROSA BRUNONII LINDL. – AN EFFICIENT BIOREAGENT FOR REMOVAL OF TOXIC DYES FROM WATER

Ripened fruits of Rosa brunonii Lindl. have been collected from Badshahithaul, located in the Chamba block of Tehri district, Uttarakhand, India. Different parts of fruits viz. whole fruit (500 mg), seeds (500 mg) and deseeded peel with pulp (500 mg), have been separately treated...

BRONCHIAL ASTHMA:: HOMEOPATHIC APPROACH

Bronchial asthma is a chronic inflammatory disease of the airways characterized by reversible airflow obstruction, bronchial hyper-responsiveness, and recurrent episodes of wheezing, dyspnoea, chest tightness, and cough. Climatic conditions, particularly the monsoon season, signi...

A PROSPECTIVE OBSERVATIONAL STUDY ON EVALUATION OF RATIONAL USE OF ANTIBIOTICS, OUTCOME AND IMPACT OF PATIENT EDUCATION ON MEDICATION ADHERENCE AND QUALITY OF LIFE IN PNEUMONIA PATIENTS IN A TERTIARY CARE HOSPITAL: A PILOT STUDY.

Background: Pneumonia is a major cause of morbidity and mortality worldwide and is commonly treated with antibiotics. Irrational antibiotic use contributes to antimicrobial resistance, prolonged hospitalization, increased healthcare costs, and poor clinical outcomes. Clinical pha...

A RANDOMIZED OPEN LABELLED CONTROLLED CLINICAL STUDY TO EVALUATE THE EFFICACY OF AMLAKYADI GHRITA AND SHATAVARI GHRITA NASYA IN THE MANAGEMENT OF RAJONIVRITTIJANYA LAKSHANAS W.S.R. POST MENOPAUSAL SYNDROME

Background: Menopause is a physiological transition characterized by permanent cessation of menstruation due to ovarian follicular depletion and declining estrogen levels. The associated vasomotor, psychological, musculoskeletal, and urogenital symptoms substantially impair the q...

CLINICAL OUTCOMES OF INDIVIDUALIZED HOMEOPATHIC TREATMENT COMBINED WITH ARDHA SARVANGASANA IN PATIENTS WITH LOWER LIMB SWELLING, CELLULITIS, VARICOSE VEINS, AND VARICOSE ULCERS: A PROSPECTIVE OBSERVATIONAL STUDY

Chronic venous disorders include lower-limb edema, varicose veins, cellulitis, and venous ulcers. Venous hypertension, valve incompetence, impaired calf-muscle pump function, inflammation, obesity, prolonged standing, age, pregnancy, and previous deep vein thrombosis are recogniz...

GAS CHROMATOGRAPHIC METHOD DEVELOPMENT AND VALIDATION FOR QUANTITATIVE ANALYSIS OF LYSERGIC ACID DIETHYLAMIDE IN ILLICIT PREPARATIONS

The objective of this study was to develop and validate a simple and reliable GC-FID method for quantitative determination of Lysergic acid diethylamide in illicit drug samples. Chromatographic conditions and detection parameters were optimized. Separation was performed on a HP-5...