Research works

Uncovering the scale and link of two SARS-CoV-2 outbreaks in nursing homes by combining integrated genomic surveillance, contact tracing, and point-of-care testing

Abstract Aim The local public health authority (LPHA) in Duesseldorf received notification of two SARS-CoV-2 outbreaks in nursing home A and nursing home B in October 2021 and embarked on an outbreak investitation to identify the source of the outbreak and epidemiological links b...

The effect of Midwifery continuity of care on maternal outcomes among women with psychosocial risk factors in Sweden: A registry-based cohort study

BACKGROUND: Women identified with psychosocial risk factors are at higher risk of interventions during labour and birth and adverse maternal outcomes. Midwifery Continuity of Care (MCoC) reduces interventions and improves maternal outcomes among low-risk women; however, evidence...

Understanding and Applying Useful Instruments to Evaluate Bipolar Spectrum Disorder

Bipolar disorder, a chronic and recurrent psychiatric illness, is characterized by substantial diagnostic challenges and heterogeneous clinical manifestations.Because patients often present during depressive episodes and may not recognize previous hypomanic symptoms, standardized...

Query-Relative Soundness of Legal-Reply Compression in Shogi : Quotient Criteria, Canonical Repair, and Action-Edge Counterexamples

Compressing a finite set of legal Shogi replies into coarse classes can reduce the amount of downstream checking, but such compression is meaningful only relative to what is being asked about those replies. We formalize this point as a query-relative quotient condition. For a pos...

Mechanistic insights, clinical significance, and management strategies for postgastrectomy hypoglycemia in gastric cancer patients in the era of continuous glucose monitoring: a narrative review

Purpose: Postgastrectomy hypoglycemia (PGH) is increasingly recognized as a potential metabolic complication after gastrectomy for gastric cancer. This narrative review summarizes its clinical relevance, underlying mechanisms, and management strategies in the era of continuous gl...

Multi-Layered Electrospun Scaffold Design Strategies Targeting Osteosarcopenia

Osteosarcopenia, the concurrent deterioration of bone density and skeletal muscle mass and function, represents a growing clinical challenge in ageing populations worldwide. Conventional single-tissue therapeutic approaches fail to address the intricate biochemical and mechanical...

Glomerular hyperfiltration in dipstick-negative type 2 diabetes mellitus: a novel determinant of kidney function decline in type 2 diabetes mellitus

Background: The independent impact of type 2 diabetes mellitus (T2DM) on kidney outcomes beyond albuminuria remains unclear. We evaluated whether T2DM affects kidney outcomes in individuals with normal kidney function without albuminuria. Methods: Data from the National Health In...

Strain-release photocatalytic access to rigidified isosteres of bicyclic heterocycles

We present the synthesis of fused isoxazolidine-pyrrolidine architectures via a dual rigidification strategy. These frameworks are accessed through an atom-economical approach using variously substituted isoxazolines and bicyclo[1.1.0]butane (BCB) derivatives under mild condition...

Explainable ensemble machine learning for dissolved oxygen prediction in a reservoir using SHAP and chord diagram analysis

Dissolved oxygen (DO) is a key indicator of reservoir water quality and ecosystem integrity. The dynamics of DO are governed by complex physical, chemical, and biological reactions such as thermal stratification, nutrient interactions, photosynthesis, respiration, and microbial d...

Plants, soil, and coexistence: an alternative approach to modelling plant-soil feedback

Abstract Background and Aims Plant-soil feedback (PSF) affects plant coexistence and diversity. Although the current paradigm provides a direct experimental method to quantify PSF and explains coexistence with varying levels of success, the emphasis on pairwise interactions hinde...

Implementation strategies and adjunctive interventions for HIV testing and linkage-to-care in the United States: a systematic review

Ending the HIV Epidemic in the United States depends on expanding HIV testing and rapidly linking people to care. However, methods to improve testing and linkage-to-care are inconsistently described and often conflate health system–level implementation strategies with recipient-d...

Role of sodium hypophosphite on morphology and corrosion resistance of Ni-P coated Nd-Fe-B

Uniform and dense electroless nickel (EN) was recognized as a promising protective coating for Nd-Fe-B magnets. However, large potential difference between intergranular phase and main phase of Nd-Fe-B made the deposition of EN coating uncontrollable. Sodium hypophosphite was use...

From 5Cs to ABC: operationalizing the AAP guidelines into the MEPA-ABC scale for parental mediation of children’s digital media use

Parental regulation of children’s digital media use is central to healthy development, yet existing instruments are often lengthy or only loosely aligned with contemporary clinical frameworks. The American Academy of Pediatrics (AAP) formulated the 5Cs of Media Use (Child, Conten...

Field evaluation of Pix4D viDoc for retaining wall inspections

Reliably accurate documentation of retaining wall conditions is necessary for managing long-term infrastructure health and maintaining public safety. Current visual inspection practices lack the precision and consistency needed to detect early signs of change in a structure. This...

Antidepressant Use During Pregnancy: An Evidence-based Review of Risk–Benefit Balance and Drug-specific Considerations

Antenatal depression affects approximately 12% of pregnancies, and antidepressant exposure during pregnancy-predominantly selective serotonin reuptake inhibitors (SSRIs)-is estimated at approximately 3% of pregnancies in multinational estimates.Clinical decision-making requires b...

Leak-safe functional forecasting of daily variance: window-to-curve predictors for DAX Rogers–Satchell variance

Abstract We study one-step-ahead forecasting of daily DAX equity-index variance under an explicit information-availability design. The target is the Rogers–Satchell range-based variance proxy computed from open–high–low–close (OHLC) data, and predictors are daily log returns, wit...

Factors related to prenatal depression among hospitalized high-risk pregnant women in South Korea: a cross-sectional study focused on resilience, pregnancy stress, and marital satisfaction

PURPOSE: Prenatal depression affects 10%-25% of pregnant women and has important implications for maternal and neonatal health. High-risk pregnant women may be particularly vulnerable to anxiety and depression because of obstetric complications and concerns about fetal health. Th...

Mesoporous Magnetic Nanoparticles Functionalized With Quaternary Ammonium Salts as Targeted Nanocarriers for Doxorubicin Delivery in Breast Cancer Therapy

Background: Nanotechnology offers promising strategies to overcome major limitations of conventional cancer chemotherapy, including poor targeting, systemic toxicity, and low drug bioavailability. This study focuses on developing a biocompatible magnetic nanocarrier modified with...

Derivation of Pediatric Emergency Preparedness Checklist for Urgent Care Centers

OBJECTIVES To develop a consensus-based pediatric emergency preparedness checklist tailored for urgent care centers, addressing policies, procedures, personnel, equipment, and medications necessary to stabilize critically ill or injured children prior to transfer. METHODS A modif...

The general mental health conditions and related factors of the occupational health physicians working in Ankara Province

This study aimed to evaluate the personal and occupational factors associated with the general mental health status of occupational physicians. In this cross-sectional survey, data were collected through a self-administered online survey consisting of the General Health Questionn...