Research works

HeartMate 3 in Pediatric and Complex Populations: Physiologic Rationale, Patient Selection, and Management Strategies

The HeartMate 3 (HM3) left ventricular assist device (LVAD), initially designed for adults, is increasingly utilized in children, small adults, and those with congenital heart disease (CHD), necessitating expanded knowledge and collaborative efforts. This review highlights key ph...

Science Education as Strategic Infrastructure: A Comparative Analysis of the United States, the European Union, England, Japan, and South Korea

This study presents a comparative analysis of science education policies and practices in the United States, the European Union, England, Japan, and South Korea. Rather than comparing student achievement alone, the paper examines how different education systems conceptualize the...

Enhancing optical confinement in hybrid surface plasmonic nanocavities via external mode coupling near avoided resonance crossings

Plasmonic devices have been intensively studied in the past few decades. However, the substantial intrinsic ohmic losses imposed by noble metals highly limited further applications of such devices. Herein, we demonstrate the formation of long-lived states via external mode coupli...

MINIMAX REGRET TREATMENT RULES WITH FINITE SAMPLES WHEN A QUANTILE IS THE OBJECT OF INTEREST

Consider a setup in which a decision maker is informed about the population by a finite sample and, based on that sample, has to decide whether or not to apply a certain treatment. We work out finite sample minimax regret treatment rules under various sampling schemes when potent...

Antioxidant nanozymes for regenerative medicine: mechanisms, design, and applications in tissue repair

Natural antioxidant enzymes play a central role in regulating oxidative stress within living organisms. During tissue repair following injury, these enzymes act synergistically to scavenge excess reactive oxygen species and maintain cellular redox homeostasis, thereby supporting...

Determinantal Diophantine Linear Algebra: Foundations and Lorentz--Fermat Factorization

We propose \emph{determinantal Diophantine linear algebra} as a systematic framework for integer and rational solutions of prescribed-determinant equations inside affine linear families of matrices. A datum consists of an integral affine matrix pencil\[ \mathcal A(\mathbf x)=A_0+...

Climate Impact Robust Design Optimization for Turbofan Aircraft Engine

Abstract This paper investigates robust design optimization of turbofan engines to minimize climate impact while accounting for significant uncertainties in climate models based on performance calculations. By incorporating engine performance, flight mission, emission, and linear...

Exploring how AI-integrated entrepreneurship education influences technopreneurship behavior through an integrated TAM–UTAUT-informed framework

This study aims to examine the role of AI-integrated Entrepreneurship Education (DEd) with ChatGPT as a main instrument to influence behavioral intention (BI) and technopreneurship behavior (TB). The research involved the main variables from TAM, including perceived usefulness (P...

Efficiency Analysis of Predictive Current Control of a Multiphase Drive

In Finite Control Set Model Predictive Control for multiphase drives, weighting factors govern the relative priority among the multiple objectives included in the cost function. Although their influence on control performance, harmonic characteristics, and switching behavior has...

Pan-Africanism Reimagined? Burkina Faso, Ibrahim Traoré and the Confederation of the Sahel States

Abstract Ibrahim Traoré, president of Burkina Faso since 2022, is a controversial figure: some view him as a leading figure of decolonisation, national sovereignty, and Pan-Africanism; others accuse him of authoritarianism and repression of civil society and the media. The articl...

Structure and Spatio-Temporal Dynamics of Marine Communities Associated with the Kelp Forests at Cape Froward, Strait of Magellan

Giant kelp forests, Macrocystis pyrifera, dominate the coasts of southern Patagonia and are particularly abundant in the coastal ecosystems of Cape Froward, where they play a key role in biodiversity conservation and the provision of multiple ecosystem services, establishing them...

A Research-Informed Framework for AI-Supported Business English Instruction: Integrating TED Talks, Task-Based Language Teaching, and Generative AI

This white paper presents a reusable, evidence-based instructional architecture for Business English teachers who want to integrate generative AI into lesson design without sacrificing pedagogical rigor. Synthesizing research from Second Language Acquisition, Task-Based Language...

Visual Pathways Involvement in Friedreich’s Ataxia Patients Without Macular Impairment

Objectives: Visual Evoked Potential (VEP) abnormalities in Friedreich Ataxia (FA) may result from dysfunction of retinal ganglion cells (RGC), post-retinal visual pathways, or both. Therefore, we aimed to clarify whether in Friedreich Ataxia (FA), abnormal neural conduction is du...

EuroMillions Breakthrough Mining — 1428 Sources, 9833 Leads Extracted — E8 Intelligence Research

Mined 1428 lottery+quantum breakthroughs. Extracted 9833 leads across 13 categories. 7926 high-value leads found. Categories: {"CORRIDOR": 804, "FORMULA": 656, "GEOMETRIC": 677, "FORWARD_ATTEMPT": 835, "QUANTUM": 1048, "TIMING": 179, "CELESTIAL": 744, "GEMATRIA": 789, "CONSTANT":...

The Impact of Urban Green-Space Landscape Patterns on Carbon Storage: A Case Study of Shenyang, China

Urban green-space carbon sinks can contribute to reducing urban carbon emissions and supporting carbon-neutrality goals. This study examined the associations between urban green-space landscape patterns and above-ground carbon storage (AGCS) in Shenyang. The spatial distribution...

FROM EMPIRICAL TO PATHOGENETIC CHOICE OF ANTIHYPERTENSIVE THERAPY: THE ROLE OF BIOIMPEDANCEMETRY

<p>Background. The proportion of patients with arterial hypertension achieving target blood pressure remains low, largely due to the empirical nature of therapy selection that disregards the individual haemodynamic mechanism of blood pressure elevation.</p><p style...

Machine Learning-Based Prediction of Mononuclear Cell Collection Efficiency for CAR-T Manufacturing

Abstract Objective To develop and internally validate an interpretable machine-learning model using routine precollection variables to predict mononuclear cell (MNC) collection efficiency (CE) during leukapheresis for CAR-T manufacturing. Methods This retrospective study included...

Approved Monoclonal Antibody Therapies for Hidradenitis Suppurativa

Importance Biologic therapies are increasingly used for moderate to severe hidradenitis suppurativa (HS), yet their high cost presents challenges for health systems and payers. Comparative economic evaluations of these therapies are limited. Objective To evaluate the efficiency f...

Regulation of PCSK9 During Oxidized LDL-Induced Foam Cell Formation in RAW264.7 Cells

Proprotein convertase subtilisin/kexin type 9 (PCSK9) is traditionally known for regulating plasma LDL cholesterol levels via LDL receptor degradation. This exploratory study examined the association between chemically induced changes in Krüppel-like factor 2 (KLF2), a vasoprotec...

A configurational perspective of digital transformation: uncovering the multiple pathways to digital success in an emerging economy

Purpose Digital transformation (DT) research remains fragmented as prior studies adopt linear and factor-based approaches that overlook causal complexity. Drawing on the configurational theory and critical realism, this study addresses whether and how multiple organizational cond...