Research works

Timing and Duration of Prediabetic Metabolic Dysfunction Differentially Impact Cerebral Perfusion, Vascular Structure, and Behavior

Abstract Obesity is a major risk factor for metabolic dysfunction and cognitive decline, yet the influence of age of onset and sex on neurovascular outcomes remains unclear. We examined how the age at initiation and duration of diet-induced obesity influence metabolism, cognition...

A 0.9 V Low-Power Body-Biased StrongARM Latch Comparator with Reduced Kickback Noise for High-Speed Analog-to-Digital Converters

This paper describes a low-power body-biased StrongARM (SA) latch comparator with low kickback noise, under a supply of 0.9 V for high-speed analog-to-digital converter design applications. To improve the speed of the SA latch comparator, a novel low-power clocked forward body bi...

Institutional metrics refreshed — Sharpe 1.65 · Sortino 3.8 · Calmar 1.94 — E8 Intelligence Research

{ "generated": "2026-07-26T16:51:04.332143+00:00", "method": "Out-of-sample verified weighted portfolio: sleeve weights trained on the first 70% of months only, verified on the final 30% (OOS Sharpe 1.87). Spread costs included, Dukascopy tick-derived data, 1% risk base. Member c...

EuroMillions Breakthrough Mining — 1442 Sources, 9987 Leads Extracted — E8 Intelligence Research

Mined 1442 lottery+quantum breakthroughs. Extracted 9987 leads across 13 categories. 8080 high-value leads found. Categories: {"CORRIDOR": 818, "FORMULA": 670, "GEOMETRIC": 677, "FORWARD_ATTEMPT": 849, "QUANTUM": 1062, "TIMING": 179, "CELESTIAL": 758, "GEMATRIA": 803, "CONSTANT":...

Kinematic Note 11: The Double Topological Transition - From Light to Mass (and vice versa) / Note Cinématique 11 : La Double Transition Topologique - De la Lumière à la Masse (et inversement)

In response to the conceptual limits of the Standard Model regarding the "creation" or "annihilation" of matter, this note reinterprets the equivalence equation E=mc² through the lens of symplectic geometry. Light and mass are described here not as distinct entities, but as two t...

Metal–Organic Framework‐Preserved Thermostable Microneedle Patch for Minimally Invasive Detection and Monitoring of Kidney Dysfunction

Early and decentralized biomarker detection and monitoring is essential for timely diagnosis and intervention, particularly in kidney disorders that often progress asymptomatically until irreversible damage has occurred. Here, we present a thermally resilient metal-organic framew...

Development of Sustainable Gypsum Composites Incorporating Silica Fume Waste and Fiber Reinforcement for Construction Applications

This study evaluates the feasibility of developing sustainable gypsum composites incorporating silica fume waste and fiber reinforcement for construction applications. The experimental program was divided into two phases. First, silica fume was incorporated into the gypsum matrix...

Day-to-day experiences and challenges of long-term warfarin use among patients with prosthetic heart valves at a National Cardiac Institute in Tanzania: A qualitative study

Background Long-term warfarin therapy following prosthetic heart valve placement is essential for preventing valve-related thromboembolic complications. Due to its narrow therapeutic window, maintaining a therapeutic International Normalized Ratio (INR) requires strict adherence...

MODEL-informed nivolumab less frequent dosing using virtual patients with solid tumors

Less frequent nivolumab dosing has been assessed for more efficient dosing, but there is no conclusive evidence. In this research, we suggested an appropriate model-informed drug dosing using virtual patients collected from the results of multiple clinical studies to provide a ra...

Toward smarter solar: IoT and fuzzy logic for real-time maximum power point tracking and monitoring of photovoltaic systems

Abstract Photovoltaic (PV) systems are extremely prone to wear and tear and physical damage due to large variation in environmental conditions. Integration of real-time monitoring systems with PV would be highly advantageous in detecting early faults and performance degradation c...

The Pythagorean Angle Lattice: Geometry, Algebra, and Hyperbolic Correspondence

A lattice built from the angles of primitive Pythagorean triples systematically generates algebraic, logarithmic and transcendental constants while revealing an S₃-Galois extension and a precise correspondence with closed geodesics on the modular surface : We study the Pythagorea...

A Unified Structural Model of Constraint, Stability, and Cross Domain Collapse Behaviour

This paper develops a unified structural model demonstrating how boundary conditions determine system behaviour across physical, conceptual, and hypothetical domains. Using the A–B–C boundary framework, the analysis shows that structured environments eliminate random possibilitie...

Defining a minimal clinically important difference for the Vanderbilt ADHD Parent Rating Scale in children with Attention-Deficit/Hyperactivity Disorder

Attention-deficit/hyperactivity disorder (ADHD) is a prevalent neurodevelopmental condition in children and adolescents that poses substantial challenges to health, functioning, and well-being. This study aimed to estimate the minimal clinically important difference (MCID) for th...

Adaptive-threshold max-SVM model with progressive-iterative algorithm for high-dimensional data classification and feature selection

Purpose Support vector machines have been progressively refined in existing research, but there are still certain limitations in feature selection for high-dimensional data. Design/methodology/approach This paper proposes an adaptive-threshold max-SVM model, which seeks to improv...

EuroMillions Breakthrough Mining — 1367 Sources, 9162 Leads Extracted — E8 Intelligence Research

Mined 1367 lottery+quantum breakthroughs. Extracted 9162 leads across 13 categories. 7255 high-value leads found. Categories: {"CORRIDOR": 743, "FORMULA": 595, "GEOMETRIC": 677, "FORWARD_ATTEMPT": 774, "QUANTUM": 987, "TIMING": 179, "CELESTIAL": 683, "GEMATRIA": 728, "CONSTANT":...

In Vitro Assessment of Nintedanib in Keratoconus Corneal Stromal Microenvironment

Keratoconus (KC) is a degenerative corneal disease, characterized by stromal thinning and abnormal ECM remodeling, leading to fibrosis. Corneal fibrosis is a leading cause of visual impairment. Corneal stromal keratocytes differentiate into myofibroblasts, which alters extracellu...

Simultaneity, Instantaneous Gravity, and the Measurement of Absolute Velocity: A Companion Protocol to Quantum-Geometry Dynamics

Any synchronization scheme that relies solely on light signals cannot test the isotropy of the one-way speed of light. The convention used to split a measured two-way delay into one-way components becomes, by construction, the result of the subsequent measurement. This is the cla...

Does social capital improve gender equality?

The relationship between social capital and gender equality has been studied predominantly at the micro-level with mixed but often negative results. Both mixed-gender social capital and women’s social capital do not seem to benefit women as much as men. After developing a theoret...

Online Negative Reviews and Complaints in Healthcare and Dentistry: A Narrative Review of Patient Experiences

Background: The widespread use of online review platforms has transformed how patients evaluate healthcare providers and has created a valuable source of patient-generated feedback on healthcare quality. Negative online reviews provide valuable insights into patient experiences a...

Miocene Evolutionary History Shaped the Phylogeography of Willow Species (Salix L.) in the European Alps

In the European Alps, plant species have persisted through major geological and climatic changes, leaving distinct genetic signatures of divergence. While these patterns are often attributed to Pleistocene glacial refugia, they may also reflect older, pre-Quaternary events. In mo...