Research works

Transcriptome and 16S rRNA Gene Sequencing of Grass Carp During Dietary Transition

This project contains transcriptome and 16S rRNA gene sequencing data from juvenile grass carp (Ctenopharyngodon idella) during dietary transition. Intestine and liver tissues from the NDT, HERB, and CARN groups were subjected to RNA sequencing. Intestinal contents and the associ...

Historical Anti-Fascism and Right-Wing Voting in Italy

We study how anti-fascist opposition during Mussolini’s dictatorship affects post-war support for right-wing parties in Italy. We construct a measure of anti-fascism from the universe of recorded opponents, and use newly digitized historical data to resolve simultaneity between t...

Velocity deviation-based pore type classification in an Iranian carbonate gas reservoir using multiscale integrated data

This study presents an integrated approach to pore type classification in a carbonate gas reservoir from the Dalan/Kangan formations in Iran, utilizing velocity deviation log (VDL) analysis derived from thin sections, conventional well logs, Nuclear Magnetic Resonance (NMR) data,...

Chidamide plus venetoclax as effective and safe maintenance therapy in high-risk acute myeloid leukemia and myelodysplastic syndrome post-transplantation

Abstract Relapse after allogeneic hematopoietic stem cell transplantation (allo-HSCT) remains the leading cause of treatment failure in high-risk acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS), yet effective maintenance strategies are currently lacking. The combi...

Development and validation of a two-gene urine DNA methylation assay for noninvasive prostate cancer detection: a prospective multicenter study

Prostate-specific antigen (PSA) screening lacks specificity, particularly within the 4-10 ng/mL diagnostic gray zone, leading to unnecessary prostate biopsies and overtreatment. Here, we developed and validated a streamlined urine DNA methylation assay for non-invasive prostate c...

Regulatory Manner and Role of Circular RNAs in the Microsporidian Invasion of Asian Honeybee

Vairimorpha ceranae, an obligate intracellular parasitic fungus, infects the midgut of worker Apis cerana cerana, disrupts nutritional metabolism and immune homeostasis of hosts, and poses severe threats to honeybee health and the sustainable development of apiculture. To date, t...

National health institutions and the management of COVID-19 pandemic: fulfilling the sustainable development goal three (SDG-3) in Nigeria

Abstract Background The Coronavirus Disease 2019 (COVID-19) pandemic posed significant challenges globally, testing the capacity of national health institutions to respond effectively. In Nigeria, the pandemic revealed systemic gaps but also demonstrated institutional resilience....

Recognition of ear, nose and throat involvement in patients with ANCA-associated vasculitis: from in-depth interviews to insights for the future

PURPOSE: Ear, nose, and throat (ENT) manifestations are common in antineutrophil cytoplasmic antibody-associated vasculitis (AAV). Although timely intervention is crucial, diagnosis and treatment are often delayed due to its rarity and nonspecific symptoms. Currently, no standard...

Short-term knowledge gains and learner satisfaction after a basic radiology course for family medicine residents in a 3-dimensional virtual environment: a multi-cohort pretest–posttest study in Spain

Purpose: This study aimed to evaluate a structured basic radiology course for Family Medicine residents delivered in a 3-dimensional (3D) virtual environment (Second Life). We hypothesized that participation would be associated with higher post-course knowledge test scores and hi...

Social determinants of health and lifestyle in the progression of degenerative bone and joint diseases: a prospective multi-state analysis

Abstract Aims The role of social determinants of health (SDOH) in the progression of degenerative bone and joint diseases (DBJDs) - from initial onset to multimorbidity and mortality - remains unclear. We aimed to assess the associations of SDOH with DBJDs progression, examine th...

Surgical Complexity and Postoperative Outcomes in Recurrent Versus Primary Incisional Hernias Following Elective Retromuscular Repair: A Retrospective Cohort Study

Background/Objectives: Recurrent incisional hernia remains a major challenge in abdominal wall surgery and is frequently associated with increased surgical complexity and adverse outcomes. However, its role as a distinct surgical entity and its cumulative operative impact remain...

Burden of pancreatic cancer in China and the United States, 1990–2023

Abstract Objective: Pancreatic cancer (PC) remains a major global health burden characterized by high mortality and substantial socioeconomic inequality. This study compared long-term trends, inequality patterns, and risk-factor transitions of PC burden in China and the United St...

Insulin resistance as a potential mediator between central obesity and diabetic kidney disease risk in type 2 diabetes

Abstract Obesity is a key risk factor for diabetic kidney disease (DKD). However, BMI fails to capture body fat distribution. We hypothesized that central obesity, rather than generalized obesity, is associated with DKD risk in patients with type 2 diabetes mellitus (T2DM), and t...

Autonomous Solar-Thermal MHD Desalination Node

This comprehensive engineering specification details the complete architecture, physics, and autonomous operation of a closed-loop Solar-Thermal Magnetohydrodynamic (MHD) Desalination Node designed for extreme arid environments. The system integrates four synergistic subsystems:...

Evolution of treatment distribution and patient characteristics of muscle invasive bladder cancer patients: results from two multi-national real-world surveys

To describe the real-world clinical characteristics and treatment distribution of patients with muscle-invasive bladder cancer (MIBC), and to discuss how these patterns have evolved over time. Data were drawn two separate cohorts of the Adelphi Muscle Invasive Urothelial Cancer D...

Genomic insights into replicons and conjugative transfer systems of blaNDM-positive plasmids in the Enterobacter cloacae complex

The Enterobacter cloacae complex (ECC) represents a prominent opportunistic pathogen associated with multidrug-resistant nosocomial infections. The emergence of New Delhi metallo-β-lactamase (NDM)-producing ECC isolates presents a significant threat to public health, owing to the...

Ethical Conflicts and Educational Needs of Rehabilitation Clinicians in a Teaching Hospital in Malaysia

OBJECTIVE: To identify the ethical issues encountered by rehabilitation clinicians in routine clinical practice and explore their needs and preferences for ethics education. DESIGN: A descriptive survey study. SETTING: This study was conducted in an urban tertiary teaching hospit...

Annotated dataset for retinal fundus image segmentation: vascular arcade and optic nerve head

Abstract Objectives Digital fundoscopy is an ophthalmological technique used to evaluate the posterior segment of the eye, including the retina and its anatomical structures [1]. This technique acquires fundus images, visually documenting the aforementioned structures. This datas...

Outcomes of Audiologist-Delivered Tinnitus Management in Singapore Public Health Service: A Retrospective Service Evaluation

Background/Objectives: Tinnitus can have an adverse impact on some patients’ lives, affecting the daily functioning for a proportion of patients. In recent years, audiologists in Singapore who are specialised in tinnitus and hyperacusis rehabilitation have increasingly been provi...

A GHz-Gated Dual-Anode InGaAs/InP SPAD Front-End for OAM Cat-Qubit Syndrome Extraction

The OAM cat-qubit encoding developed in a companion note [1] defines an operationalprotocol for extracting the channel’s mode-hopping rate γ from the linear growth of OAMpopulation variance, Var(l) = γz, measured via repeated single-photon counting at the outputports of a telecom...