Research works

Parathyroid hormone exposure frequency regulates spatiotemporal coupling during bone remodeling in a functional bone model

Abstract Bone homeostasis is maintained by coupling, in which osteoclast-mediated bone resorption is followed by osteoblast-mediated bone formation at the same site. Parathyroid hormone (PTH), including the PTH(1-34) analog, exerts distinct anabolic and catabolic effects on bone...

Saturation-Splitting Hypothesis: Integrated-Intelligence Saturation and the Divergence of Local Improvement in Self-Improving AI

Recursive self-improvement is often discussed as though an AI system could increase its intelligence without bound. This paper applies the author's previously proposed AI Saturation-Splitting Hypothesis to the narrower case of single-agent self-improvement. The hypothesis propose...

Age- and sex-specific predictive performance of obesity indices for hypertension in the Persian (Shahedieh) cohort study

The rising global prevalence of obesity and its associated negative health outcomes impose a substantial burden on healthcare systems. This study aimed to investigate the predictive power of obesity-related indices for hypertension (HTN) in an Iranian population. This prospective...

Spatiotemporal patch identification and multiscale drivers of nonagricultural conversion of cultivated land in the Jianghan Plain

Abstract The nonagricultural conversion of cultivated land (NACCL) poses a major challenge to cultivated land protection and food security in intensive agricultural regions. However, the reliable identification of NACCL in complex agricultural plains remains difficult because cul...

Theoretical study into a novel design of oscillating water column with high broadbanded efficiency

This paper considers the theoretical operation of a novel wall-mounted oscillating water column wave energy device designed to be resonant over a broad range of frequencies. A curved duct with a submerged opening in a vertical wall is partitioned into a number of separate narrow...

MF-DETR: an efficient end-to-end framework for small object detection in UAV imagery

Unmanned aerial vehicle (UAV) object detection plays an important role in intelligent transportation, environmental monitoring, and public safety. However, UAV images usually contain dense small objects, large scale variations, occlusion, and complex background interference, maki...

Interpretable machine learning reveals spatial drivers and regional gradients of soil organic matter across Anhui Province, China

Abstract Soil organic matter (SOM) is a crucial indicator of soil quality and carbon sequestration capacity. In regions with complex topographic and climatic gradients such as Anhui Province, the spatial patterns of SOM and its environmental controls remain insufficiently charact...

A total infectome framework for resolving complex disease etiology in aquaculture

Traditional pathogen isolation can establish disease causality but often fails in complex infections involving unknown or multiple microbial backgrounds, whereas metatranscriptomics comprehensively captures the total infectome without directly resolving the primary etiological ag...

The Read-Once Factorial-Divisibility Conjecture: Algebraic Proofs Through Six Inputs

We formulate the division-free read-once factorial-divisibility conjecture for pairwise distinct integers. Using congruence arguments, signed residue classes, parity decompositions, and disjoint block constructions, we prove the conjecture algebraically for all input sizes 1≤n≤6....

Highly DispersedCuO/ZnO Nanocomposite Supported onMgO as Catalyst for the Purification of Trioxane: Transfer Hydrogenationof Formaldehyde Impurities to Methanol

Abstract In trioxane (TOX) production, unreacted formaldehyde (HCHO) readily forms a hard-to-separate ternary azeotrope with TOX and water, impairing purification efficiency and increasing energy demand. We report a green catalytic strategy that selectively converts azeotropic HC...

Phoebe and Machilus chloroplast genomes

Phoebe and Machilus chloroplast genomes

Improved adaptation mechanism in MRAC scheme with nonlinear reference model for nonlinear uncertain systems

Abstract This paper proposes a direct Model Reference Adaptive Control (MRAC) architecture integrating a nonlinear reference model for a class of MIMO nonlinear systems with parameter uncertainty. The proposed Lyapunov-based adaptive rule makes the MRAC architecture favourable fo...

Viral transformation of stem cells into cancer stem cells and tumor enhancement by immunoexcito-oncomodulation: Accumulating evidence that most cancers are virally induced and further altered to increase their aggressiveness

The enigma of cancer development from stem cells and/or somatic cells has now been questioned, primarily by Thomas Seyfried and co-workers. From a genetically triggered disorder, they have made a powerful case for a metabolic origin or cancer. In this paper I make a case for a vi...

Machine learning force field molecular dynamics simulation of SEI formation on lithium metal

Abstract Lithium metal batteries represent a cornerstone technology for next-generation energy storage systems owing to their exceptional energy density. However, the extreme reactivity of lithium metal drives continuous parasitic reactions with electrolytes, causing interfacial...

Q-VOLT: A Quantum–Classical Pipeline for Multi-Period Data-Center Siting on the IEEE 30-Bus System

Q-VOLT is a hybrid quantum–classical pipeline for the multi-period data-center siting-and-scheduling problem on the IEEE 30-bus system with real California-ISO locational-marginal-price data and published hyperscale workload traces. I formulate the problem as a QUBO with per-job...

Isolated retroiliac ureter causing hydronephrosis in a young adult female: a case report

Abstract Background A retroiliac ureter is an exceptionally rare congenital anomaly characterized by a posterior course of the ureter relative to the iliac vessels. Its nonspecific clinical and radiological features frequently lead to misdiagnosis, and definitive diagnosis is oft...

Utilising virtual environments to assess the visibility of fallow deer to human hunters

Abstract Visual detection of prey is a critical element of human hunting behaviour. We examine how factors such as prey coat colouration, distance to the observer and orientation influence the ability of humans to visually locate fallow deer in simulated virtual environments. The...

Evolution of functional and mental status and quality of life in people aged 75 years and over after the COVID-19 pandemic in Spain: a prospective cohort study

The COVID-19 pandemic has had significant health and psychosocial consequences in the older adults. However, there is little community-based evidence that clearly distinguishes the effect attributable to SARS-CoV-2 infection to be differentiated from the contextual impact of the...

Diffusion in deforming semi-permeable media: a Monte Carlo random walk approach

Abstract Diffusion processes in deforming media with semi-permeable barriers are fundamental to understanding many biological and physical systems. The presence of semi-permeable barriers causes temporal and spatial departures from normal diffusion. We present an analytic express...

Maternal immune activation disrupts the kynurenine pathway of tryptophan metabolism in the placenta–fetal brain axis in rats

Abstract Background Maternal immune activation is a major risk factor for neurodevelopmental disorders; however, the molecular mechanisms linking gestational inflammation to fetal brain vulnerability remain incompletely defined. The tryptophan–kynurenine pathway is highly respons...