Research works

The WIPO Treaty on Intellectual Property, Genetic Resources, and Associated Traditional Knowledge: Miracle or Mirage?

Abstract On 24 May 2024, member states of the World Intellectual Property Organization (WIPO) concluded a new treaty. This is the first WIPO treaty in over a decade and will establish, under international law, a disclosure requirement for patent applicants whose inventions are ba...

Mutual Altruism and the Principle of Economic Priority

This monograph examines the possibility of sustaining altruistic behavior within a social and economic environment in which economic benefit remains a primary and, in practice, unavoidable incentive. The central concept proposed in the work is mutual altruism conditioned by econo...

Global Immunization Coverage Saw Gains in 2025, But Experts Warn of Trouble Ahead

This Medical News article discusses the latest global immunization coverage estimates released by the World Health Organization and the United Nation Children’s Fund.

An Improved Antarctic Sea Ice Thickness Dataset Derived from CryoSat-2 Using LightGBM

Abstract Sea ice is crucial for modulating Antarctic air–sea fluxes, and its thickness (SIT) is the primary factor controlling the exchange of heat, moisture, and momentum. Although CryoSat-2 is commonly used for SIT retrieval, conventional algorithms rely on empirical parameters...

Policy (dis)integration in water management: a historical analysis of a Swiss case

Abstract Over the past 170 years, water management in Switzerland has undergone a profound transformation. What began as a localized, event-driven practice shaped by immediate needs and local initiative—such as efforts to ensure flood protection—gradually evolved into a complex,...

Sequential FIB-4–based testing limits detection of fibrotic MASLD despite optimized ELF thresholds

Background: Societal guidance recommends sequential noninvasive testing for metabolic dysfunction–associated steatotic liver disease (MASLD), using Fibrosis-4 (FIB-4) ≥1.3 as a gatekeeper before second-line assessment with the Enhanced Liver Fibrosis (ELF) score (<7.7 as a rul...

Oceanic Thermal and Storm Dynamic Controls on Precipitation Variability of Landfalling Typhoons in Zhejiang Province, China (2000–2025)

Landfalling typhoons frequently cause severe flooding and socioeconomic losses along the eastern coast of China, yet the relative influence of oceanic and storm-related factors on precipitation variability remains insufficiently understood. This study investigates the relationshi...

"Critical Language Ecosystem": About Truth, Power, and Digital Media from a Marxist Critical Philosophy Approach

Language is a product of labour, both a means of expressing the truth and a potential means of hiding and distorting reality. In the context of digital media and artificial intelligence, the dialectical movement between language's truth and falsehood becomes a central issue in in...

Utility of Prognostic Staging Systems in Transthyretin Amyloidosis Cardiomyopathy in the Era of Available Disease‐Modifying Treatment

Background Prognostic staging systems in transthyretin amyloid (ATTR) cardiomyopathy were developed before the introduction of disease‐modifying treatment. We therefore evaluated contemporary risk stratification according to different staging systems in patients with ATTR cardiom...

Distinct Yet Coordinated: Pattern of Leaf and Root Fungal Endophyte Communities in an Alpine Meadow

Leaf and root fungal endophytes (LFEs and RFEs) represent essential yet distinct components of the plant holobiont, but their ecological relationships remain poorly understood. Here, we investigated the community structure of LFE and RFE across 45 plant species in an alpine meado...

Autonomous Constraint Recognition Protocol Layer

**Autonomous Constraint Recognition Protocol Layer** presents a foundational cybernetic protocol (ACRPL) that redefines digital governance by enforcing a strict computational separation between optimizable variables and unoptimizable variables within AI-assisted decision-making....

A case of mucopolysaccharidosis I with severely increased albuminuria and Graves’ disease, and functional analysis of previously uncharacterized variant

Abstract Background Mucopolysaccharidoses (MPS) are a group of inherited lysosomal storage disorders which results in accumulation of glycosaminoglycans throughout the body. MPS I is a subtype characterized by mutations in the α-L-iduronidase (IDUA) gene with subsequent multiorga...

CosmoBeating • Fungal Geometry and Topology — Sub-Paper III: Biodiversity

CosmoBeating — Fungal Geometry and Topology (CB-FGnT)A Complex-Systems Reading of Fungal Networks This is a short, non-technical companion to the 15-paper CB-FGnT series. It is written for readers with a background in mycology, network science, or complex systems — not for reader...

Oral Microbiome Resilience: From Ecological Stability to Precision Oral Healthcare

Introduction: The concept of oral microbiome resilience has emerged as a new paradigm that emphasizes the ability of the oral microbial ecosystem to maintain ecological stability and recover from environmental disturbances. This concept provides a broader perspective than dysbios...

Beyond Static Expertise : Unpacking Live-Streamer Professionalism as Contextual Competence in Interactive Commerce

Traditional celebrity endorser models conceptualize expertise as a static trait focused on the possession of product knowledge. However, the synchronous and highly interactive nature of live commerce challenges these static models in explaining consumer engagement. Grounded in So...

SYSTEM EVOLUTION PROPOSALS (rlab #97) — E8 Intelligence Research

- Add a numeric ratio extractor agent that parses Carlson-style presentations for phi, pi, sqrt2, sqrt3, and precessional numbers - Implement a Fourier analysis pipeline for monument dimensions against E8 root length ratios - Create a cross-reference table between precessional nu...

EuroMillions Breakthrough Mining — 1527 Sources, 10821 Leads Extracted — E8 Intelligence Research

Mined 1527 lottery+quantum breakthroughs. Extracted 10821 leads across 13 categories. 8895 high-value leads found. Categories: {"CORRIDOR": 889, "FORMULA": 740, "GEOMETRIC": 690, "FORWARD_ATTEMPT": 928, "QUANTUM": 1138, "TIMING": 186, "CELESTIAL": 829, "GEMATRIA": 877, "CONSTANT"...

Metal-Free Disulfonylationof Terminal Allenes

Abstract A facile and efficient metal-free protocol for the highly regio- and stereoselective disulfonylation of terminal allenes has been established herein, which enables the straightforward synthesis of structurally diverse (E)-1,2-disulfonyl allylic derivatives in satisfactor...

Beyond Forest Expansion: State Forest Land Acquisitions as an Instrument of Sustainable Land Governance

Land-use conflicts in non-urbanized areas are fundamentally governance problems rather than purely environmental ones: sustainability outcomes increasingly depend on integrated, cross-sectoral decision-making reconciling forestry, agriculture, tourism, infrastructure, and urbaniz...

Causal association between air pollution and functional outcome after ischemic stroke: Evidence from 2-sample MR study

Observational studies have shown that air pollution may affect functional outcome following ischemic stroke. Our study aimed to explore the relationship between genetically predicted specific air pollutants and poststroke functional outcomes using the Mendelian randomization (MR)...