Research works

The chromatin-organizer Satb1 modulates regulatory T cell activity within the tumor microenvironment

Regulatory T cells (Tregs) are essential for maintaining immune homeostasis and preventing autoimmune diseases, but are also a major cellular constituent of the tumor microenvironment (TME) that facilitates cancer progression. Identifying differences in Treg subtypes to specifica...

Transient receptor potential channel activation targets multiple stages of the schistosome parasite

Schistosomiasis, a neglected tropical disease caused by infection with parasitic blood flukes of the genus Schistosoma , affects more than 250 million people worldwide. Currently, patients rely on a single medicine, praziquantel (PZQ), discovered half a century ago. To combat dru...

Association of PTH1R Gene Polymorphisms with Three-Dimensional Mandibular Morphology Across Three Recruitment Cohorts

Parathyroid hormone 1 receptor (PTH1R) regulates chondrocyte differentiation and mandibular condylar cartilage development, but its contribution to adult mandibular morphology remains unclear. We investigated associations of two PTH1R single-nucleotide polymorphisms (SNPs), rs724...

Hierarchical Core‐Shell Phase‐Change Fibers for Active‐Passive Thermal Management, Multimodal Sensing, and Infrared Camouflage

ABSTRACT The continuous development of smart textiles calls for multifunctional fibers that can simultaneously achieve thermal energy storage, active heating, and real‐time sensing. Using an emulsion‐based wet‐spinning strategy, thermoplastic polyurethane/octadecane/poly(3, 4‐eth...

Mass Protest and Civil Society Positioning in Romania

Romania's contentious politics has been undergoing significant change in recent times, most visibly marked by repeated cycles of mass protest. Based on political ethnographic research conducted in Romania, this study conceptualises this process by exploring activists’ meaning-mak...

DOE‐Based Sensitivity Analysis for Rational Constitutive Parameter Selection in Coupled Hydro‐Mechanical Simulations of Test in Unsaturated Soils

ABSTRACT The Barcelona Basic Model (BBM) is the most well‐known elasto‐plastic constitutive model for describing the behavior of unsaturated soils. However, the selection of BBM parameters from laboratory data remains challenging due to the strong coupling and interdependence amo...

Double-Lock Superpolymer TDN is Used for the Theranostics of HCC

Abstract Hepatocellular carcinoma (HCC) is difficult to diagnose early and treat effectively due to its heterogeneity and lack of highly specific biomarkers. Here, we develop a double-lock superpolymer tetrahedral DNA (TDN) integrated with small extracellular vesicles (SUPDIA) fo...

Influence of Shelf-Aging on Resistive Switching Characteristics of Sol–Gel-Processed ZnO and Al-Doped ZnO Structures

Sol–gel-processed zinc oxide (ZnO) is indispensable in various optoelectronic applications, such as quantum dot light-emitting diodes (QLEDs), due to its high electron transport capability and adjustable oxygen vacancy characteristics. However, its commercialization has been dela...

Interactions Among Three‐Tier Factors of Community Safety Resilience: A Dual‐Perspective Analysis

ABSTRACT Enhancing community safety resilience (CSR) is critical for sustainable urban development. Disregarding the complex interactions among CSR factors may cause imbalanced resilience building, limiting a community's capacity to respond to uncertain disasters. This study aims...

Yellow‐Green Fluorescence in Sebaceous Carcinoma Under Ultraviolet‐Induced Fluorescence Dermoscopy

Paweł Pietkiewicz is the President of the Polish Dermatoscopy Group and the National Representative (Poland) of the International Dermoscopy Society. He is an adviser for HEINE Optotechnik GmbH & Co. KG; he has received honoraria from HEINE Optotechnik GmbH & Co. KG, speaker fees...

β-XGCH TEKSHIRUVI NATIJASI MUSBAT BO‘LGANIDAN KEYIN ERTA REPRODUKTIV YO‘QOTISH XAVFINI BASHORATLASH MODELI

β-XGCh tekshiruvi natijasi musbat bo‘lganidan keyin erta reproduktiv yo‘qotish xavfini bashoratlash uchun matematik model ishlab chiqildi. Homiladorlik yakuni ma’lum bo‘lgan 62 nafar ayolning ma’lumotlari tahlil qilindi. Dastlabki ma’lumotlar bazasiga anamnez, klinik xususiyatlar...

Creating an Ear and Hearing Health Culture for Professional Ear Users: Current Perspectives on Challenges, Management, and Recommendations

Professional ear users (PEUs), including musicians, instrument makers, or sound engineers, depend on highly trained auditory abilities for occupational performance. Given these demands, PEUs may benefit from tailored prevention, diagnostics, and treatment. Ear and hearing disorde...

Reverb, Chillwave, and the Disinterested Hipster

Abstract This article examines the role of reverb in shaping the sonic and cultural identity of chillwave, a genre that emerged in the late 2000s and became emblematic of the disinterested hipster aesthetic. Focusing on the production techniques in tracks by Washed Out and other...

Modeling and hierarchical energy storage dispatch control of a pulverized coal buffer unit for flexible operation of coal-fired power plants

With the increasing integration of renewable energy, coal-fired power units require higher operational flexibility. However, the delays caused by raw coal grinding and pulverized coal transport in conventional direct fired pulverizing systems limit rapid load response. To address...

Evaluation of liquid equation of state for deuterium oxide (D2O) and perfluorooctane (C8F18) via tamped Richtmyer–Meshkov instability experiments

Window materials in shock compression experiments maintain shock stresses in samples and enable optical velocimetry measurements of the sample–window interface. Transparent liquids present unique opportunities as negligible-strength window materials that conform to nonuniform sur...

Progesterone Modulates Protein Synthesis in Osteoarthritic Fibroblast-like Synoviocytes

Knee osteoarthritis (OA) is highly prevalent in women and is characterized by structural joint alterations and synovial inflammatory processes that contribute to pain and impaired mobility. In a previous study, we identified a positive correlation between progesterone levels and...

Constant to change: can a stable management team best drive digital development?

Purpose This study aims to investigate the impact and underlying mechanisms of top management team (TMT) stability on firm digital development, addressing a significant gap in the literature regarding how stable leadership shapes corporate digital transformation. Design/methodolo...

Palynology of Malpighiaceae Juss. In an Area of Ferruginous Campo Rupestre In The Iron Quadrangle, Southeastern Brazil

Serra do Pires, in the Iron Quadrangle (Southeastern Brazil), is a preserved area of ferruginous campo rupestre in a region marked by intense mineral extraction. Malpighiaceae is represented in the area by 14 species whose pollen grains were analyzed to assess their contribution...

Fasting proinsulin as a predictor of future glucose tolerance deterioration in Japanese adults

ABSTRACT Aims/Introduction Proinsulin is associated with β‐cell stress and has been linked to subsequent deterioration in glucose metabolism in Western populations, but its predictive value in Asian populations remains unclear. We investigated whether proinsulin is associated wit...

Morphological, genetic, and phenolic characterization of Baccharis glutinosa and Baccharis salicifolia and their application in the biogenic synthesis of silver nanoparticles

The genus Baccharis exhibits high taxonomic diversity and marked morphological plasticity, which complicates the species-level delimitation of closely related taxa. In this study, an integrated characterization of Baccharis glutinosa and Baccharis salicifolia collected in the La...