Research works

Development of Novel Triangular Single-Layer Separation and Recombination Inspired Micromixers Integrated with The Minkowski Fractal Principle

Abstract The present work proposes and numerically investigates a series of novel passive micromixers based on the triangular-shaped separation and recombination (TSAR) configuration. These designs are further integrated with the Minkowski fractal principle into the triangular ob...

Energeticsof Formation and Fragmentation of Carbon-CenteredRadicals α- to Nitrogen and Oxygen in N , N , O -Trimethylhydroxylamine in Comparisonto Trimethylamine and Dimethyl Ether: Implications for Medicinal andSynthetic Chemistry

Abstract α–C–H bond dissociation energies (BDEs) have been computed for N,N,O-trimethylhydroxylamine, trimethylamine, and dimethyl ether, leading to the conclusion that there is no advantage to hydrogen abstraction from trisubstituted hydroxylamines over the corresponding tertiar...

Incomplete male puberty: a new nosographic entity

Abstract Purpose Incomplete male puberty is a recently proposed nosographic entity defined by the development of normal secondary sexual characteristics in boys who nonetheless fail to achieve adequate testicular volume (<12 mL) during puberty due to underlying Sertoli cell dy...

EuroMillions Breakthrough Mining — 1569 Sources, 11207 Leads Extracted — E8 Intelligence Research

Mined 1569 lottery+quantum breakthroughs. Extracted 11207 leads across 13 categories. 9264 high-value leads found. Categories: {"CORRIDOR": 924, "FORMULA": 772, "GEOMETRIC": 696, "FORWARD_ATTEMPT": 964, "QUANTUM": 1176, "TIMING": 190, "CELESTIAL": 860, "GEMATRIA": 914, "CONSTANT"...

Cyclic Transformational Universe Model: A Mathematical Framework for a Closed Cosmological Model with a Transformational Region

We present a mathematical framework for a cyclic transformational cosmological model in which the universe is treated as a single closed system with no external space or external temporal ordering. The model introduces one transformational region, termed the supersingularity, whi...

A Computational Bioinformatics Approach for Analysis of DNA and Protein Sequences Using Biopython

The rapid development of genomic technologies has resulted in the generation of large amounts of biological sequence data. Efficient analysis and interpretation of this information require computational approaches that combine biology, computer science, and data analysis. Bioinfo...

Continual learning for autoregressive PDE surrogates under evolving physical regimes

Abstract Deploying machine learning surrogates in scientific simulations faces multifaceted challenges, primary among which is the lack of Continual Learning (CL) capabilities—specifically, the inability to adapt to new physical regimes without significantly degrading performance...

Association between risk of eating disorders and an unhealthy lifestyle score in university students: uniHcos project

Introduction The first year of university is a critical period for the consolidation of lifestyle habits and has been associated with an increased risk of developing eating disorders (EDs). This study aimed to assess the prevalence of ED risk among first-year Spanish university s...

A community-based online machine learning platform for predicting rapid decline in kidney function: a nationwide cohort study

Rapid decline in kidney function (RDKF) is an early and modifiable precursor of chronic kidney disease, yet proactive risk identification remains limited in community-based populations. This study aimed to develop, validate, and deploy an interpretable machine learning model to p...

Graphitic Grain‐Network Nanoarchitecture for Ultrahigh‐Rate and Exceptionally Durable Potassium Ternary Intercalation

ABSTRACT Potassium–ternary graphite intercalation compounds (K + ‐T‐GICs) are promising high‐power potassium‐ion storage materials, but their low reversible capacity and poorly understood electrolyte‐dependent behavior have limited their practical viability. Herein, this sensitiv...

The Correction Is Accepted, but the Premise Persists

This record includes the English edition and the Japanese source-language edition. The Japanese edition served as the semantic reference during preparation.

Meaning, Opacity, and Function: An Observer-Relative Classification of Artifacts

Every working epistemic system – a research group, a software stack, a model with its operators – holds artifacts it uses without understanding: models invoked through interfaces, cryptographic routines run as black boxes, legacy code executed daily. Whether an artifact is unders...

Golden Ratio as Universal Recurrence Constant and Photonic Bandgap Optimizer — E8 Intelligence Research

FINDING: Golden ratio (φ) emerges as a universal recurrence constant in infinite sequences and as a geometric ratio in pentagon diagonals, with potential application to photonic bandgap optimization in 1D photonic crystals. MATH: - Golden ratio φ = (1 + √5)/2 ≈ 1.6180339887… - Re...

Tumor-SelectiveVascular Modulation by Acid-CleavableRetro-Inverso Bradykinin Conjugates Enhances the Antitumor Efficacyof Nanomedicine

Abstract Enhancing the tumor accumulation of nanomedicines through vascular modulation represents a promising strategy to improve anticancer drug delivery. Bradykinin (BK), a potent vasoactive peptide, can enhance intratumoral blood flow and vascular permeability; however, its cl...

Riemann Hypothesis Linked to Black Hole Entropy via Spectral Geometry and Liouville Sums — E8 Intelligence Research

FINDING: Riemann hypothesis linked to black hole entropy via spectral geometry and a new arithmetical approach using Liouville partial sums. MATH: - Sufficient condition for RH: \( M(x) = \sum_{n \le x} \lambda(n) = O(x^{1/2+\epsilon}) \) where \(\lambda(n)\) is Liouville functio...

Serum decoy receptor 3 (DcR3) concentrations and associations with clinical parameters in Plasmodium vivax and Plasmodium falciparum malaria

Decoy receptor (DcR3) is a soluble member of the tumor necrosis factor receptor superfamily with immunomodulatory properties that is elevated in several inflammatory and infectious diseases. However, its role in malaria remains poorly understood. This study investigated serum DcR...

Geometric Relations between Relative Phase Difference and Hyperbolic Geometry in Special Relativity

This study presents a geometric interpretation of key relations in special relativity through relative phase difference and phase unfolding. A relative phase difference Δθ is associated with the relative state of motion between two observers, connecting the circular relations sin...

Diet-dependent, beneficial and adverse effects of rapamycin on life span of Drosophila melanogaster

Abstract Rapamycin supplementation has been reported to extend life spans in numerous species, including Drosophila melanogaster , but a recent study in this laboratory revealed a marked life-shortening effect in y w male flies. The experiments reported here were performed to cha...

E8 Lattice Chronon: Root-Phase Quantization Replaces Arbitrary Sampling — E8 Intelligence Research

The 132 Hz carrier frequency phase-locks to the E8 root lattice's 240 vectors through the Coxeter number h=30, yielding a fundamental chronon of 132/30 = 4.4 Hz (227.27ms) — not 100ms. Each root vector advances the lattice phase by 2π/240, and the 8-dimensional Weyl group orbit s...

Torsion Corridor Arithmetic Solitons in E8 Liouville Cascade — E8 Intelligence Research

At precise sub-harmonic fractions of the 132 Hz base frequency, the 60 torsion corridors of the E8 root lattice undergo a topological phase transition in their Liouville spectral cascade, generating coherent "arithmetic solitons" — localized eigenvalue packets whose topological w...