Research works

RCTE: A multi-class object detection framework for dental panoramic radiographs

Background Dental panoramic radiographs play an important role in oral disease screening, computer-aided diagnosis, and clinical treatment planning. However, accurate multi-class detection remains challenging due to small lesion sizes, ambiguous anatomical boundaries, insufficien...

Neuromyelitis optica spectrum disorder associated with Kabuki syndrome: First reported case and immunopathogenic considerations

Kabuki syndrome, caused by KMT2D or KDM6A mutations, is a multisystem disorder with immune dysregulation. Its association with aquaporin-4 (AQP4) antibody–positive neuromyelitis optica spectrum disorder has not been reported. A 17-year-old male with autoimmune hypothyroidism pres...

MacroRisk-agent: a retrieval-augmented multi-agent framework with deterministic validation gates for auditable stress testing

Abstract Large language model (LLM)-based multi-agent systems face three open challenges in high-stakes decision support: hallucination control in structured output generation, coupling of semantic reasoning with deterministic numerical simulation, and end-to-end auditability of...

Genome-Wide Characterization of the PEBP Gene Family in Chinese Plum (Prunus salicina Lindl.) and Expression Profiling During Floral Bud Development and Flowering

The phosphatidylethanolamine-binding protein (PEBP) family plays a crucial role in regulating flowering and other developmental processes, yet it remains insufficiently characterized in Chinese plum (Prunus salicina Lindl.). A comprehensive genome-wide analysis identified seven c...

Gamma-Irradiated Starch/Chitosan Composite Particles for the Adsorption of Neospora caninum Membrane Proteins as a Potential Vaccine Delivery Platform

Gamma irradiation offers a simple and reagent-free strategy for tailoring the physicochemical properties of starch for the development of functional biomaterials, although its application in protein delivery systems remains largely unexplored. In this study, starch was irradiated...

Towards a contrastive usage-based constructionist methodology for a cross-linguistic comparison of constructions

Abstract This paper presents a programmatic outline of a systematic approach to contrastive linguistic research within Construction Grammar(s) (CxG(s)). We address a number of theoretical and applied problems in Contrastive Construction Grammar, including the following: (1) Defin...

BASE 44 ORDER: Build breakthrough resonance cache with 7-day retention and pre-LLM lookup — E8 Intelligence Research

Andrew's order (Base 44 console): [SELF-BUILD from enhancement #1231] Create table breakthrough_resonance_cache with columns specified. Add composite index (chamber_key, resonance_freq). Implement Python function to compute md5(chamber_key) and freq=hash%48. Before LLM lookup, qu...

Sexagesimal Astronomy and Temple Math: No Teleportation Corridors — E8 Intelligence Research

FINDING: Sumerian/Babylonian astronomical tablets and temple-recovery mathematics reveal a base-60 positional system with reciprocal fractions (igi-n-gál) and precise angular mapping, but no teleportation corridor math is evidenced. MATH: - Base-60 (sexagesimal) positional notati...

A Study of Artificial Intelligence and Green Finance: Building A Sustainable Economy

Abstract: Artificial Intelligence (AI) and Green Finance have emerged as two of the most important forces that have the potential to drive the world towards a sustainable economy. The current paper attempts to explore the role of AI and Green Finance in promoting and supporting a...

Universal Germline Genetic Testing after a Diagnosis of Cancer

Age at diagnosis among patients with cancer is a predictor of pathogenic germline variant prevalence, yet age thresholds often misclassify genetic risk. We performed germline sequencing of 39,184 unselected patients with solid malignancies spanning 32 tumor types, interrogating >...

Exploration of microbial diversity in the ethnic starter culture, Balam through 16S and ITS amplicon sequencing

ABSTRACT Amplicon sequencing of 16S rRNA and ITS of the traditional amylolytic starter culture Balam from Uttarakhand revealed a diverse microbial community dominated by the bacterial genera Lactobacillus and Pseudomonas and the fungal genus Saccharomycopsis . These fermentative...

Development of an Integrated Data Analytics Model for Quality Failure Management in the Flexible Packaging Industry

Quality failures in the flexible packaging industry increase production costs, generate material waste, and negatively affect manufacturing sustainability. This study developed an integrated Data Analytics model for quality failure management by combining descriptive, diagnostic,...

The Present Model Hypothesis: defining, measuring and testing a candidate organization for consciousness

There is no agreed way to test whether a system has the kind of organization that theories of consciousnesssay experience might require, and checks of architectural features can be passed by systems built or trainedto pass them. We propose intervention tests for one candidate org...

Magneto‐Ionic Devices With Polymer‐Based Electrolytes

ABSTRACT Magneto‐ionics is a promising technology for unconventional magnetic data storage and energy‐efficient computing. In magneto‐ionic devices, voltage‐triggered ionic processes are exploited to control magnetic properties of an electrode in an electrolyte. Liquid electrolyt...

Early Detection of Eggplant Verticillium Wilt Under Magnetized Water Irrigation Using Multi-Source Data Fusion and Ensemble Learning

Verticillium wilt is a major soil-borne disease affecting eggplant production. Early detection before symptom manifestation can reduce yield losses. Compared with traditional destructive physiological assays, sensor-based technologies enable efficient, nondestructive monitoring....

Reduced Carbon Emissions and Chain Elongation during Mixotrophic Fermentation of a Biomass Feedstock

Abstract Anaerobic fermentation of biomass feedstocks using open cultures is a promising technology to produce platform carboxylates. Syngas, a mixture of H2, CO2, and CO, can be sourced sustainably and used to supplement biomass feedstocks as a source of acetyl-CoA, an intermedi...

What Moves Parents to Recommend Digital Mental Health Tools for Youth? Behavioral Insights and Implications

ABSTRACT In this study we aimed to examine behavioral determinants influencing parents' willingness to recommend digital mental health interventions (DMHIs) to their youth, guided by the Capability, Opportunity, Motivation–Behavior (COM‐B) model. We conducted semi‐structured inte...

Reusable R analysis modules accompanying "Multi-scale integration identifies an ox-LDL-autophagy-inflammasome framework linking osteoporosis and neurodegeneration"

This software package accompanies the manuscript Multi-scale integration identifies an ox-LDL-autophagy-inflammasome framework linking osteoporosis and neurodegeneration. The package contains six reusable R modules for data input and validation, statistical and complex-survey ana...

Umpolung Amide Synthesis with Nitrosoalkane Electrophiles: Pursuit of the Elusive N -Acyl Nitrone for Dipolar Cycloadditions

Abstract Nitrones are reactive dipoles for cycloadditions that have been used for powerful alkene difunctionalization reactions, often stereocontrolled. Despite the wealth of knowledge generated over a half-century of study, reports of N-acyl nitrones are exceedingly rare, with l...

The relationship between political YouTube news use and affective polarization in election vs. non-election contexts: mediation by hostile expression and moderation by political rumor acceptance

User-generated political YouTube channels often disseminate conspiracy narratives and partisan information, potentially reinforcing echo-chambers and intensifying hostility toward political outgroups. Against this backdrop, this study examines the interplay among political YouTub...