Research works

Reversible Redox Cycling: A Mechanism for Toxification and Detoxification in Fungal Alkyl Salicylaldehyde Biosynthesis

ABSTRACT Understanding how natural product producers tolerate the reactive and toxic compounds they synthesize contributes to discovering novel therapeutics and deciphering unusual biosynthetic mechanisms. Alkyl salicylaldehydes are secondary metabolites widely distributed in fun...

Multi-Source Heterogeneous Vector Coalescing and Cloud-Native LLM Orchestration in Global Distribution Infrastructure Telemetry

The integration of real-time capacity optimization suites within legacy civil aviation computing ecosystems is highly bottlenecked by the severe structural heterogeneity of distribution data infrastructures. Telemetry and transactional feeds remain highly siloed across disparate...

Quantitative Assessment of Segmentation Accuracy in Single-Source and Multisource Cone-Beam CT

Objective: Conventional single-source cone-beam CT (CBCT) is affected by x-ray scatter and cone-beam artifacts that limit quantitative structural measurements. This study compared single-source CBCT with a multisource CBCT (ms-CBCT) architecture based on a carbon nanotube x-ray s...

UniMind: A Middleware Framework for Bridging Classical AI Workloads and Quantum Computing Backends

As quantum computing transitions from theoretical research to practical deployment, a compatibility gap emerges between classical AI software stacks and probabilistic quantum hardware. Existing quantum machine learning frameworks operate at the application level and lack system-l...

Risk of protein intake deficiency during treatment with GLP-1 and GIP/GLP-1 receptor agonists: considerations for secondary sarcopenia

Sarcopenia, characterized by the age-related decline in muscle mass and strength, increases the risk of falls, fractures, disability, and mortality. Type 2 diabetes and obesity frequently coexist with sarcopenia, contributing to the growing clinical challenge of sarcopenic obesit...

“My heart is at peace because I know that I am protected:” understanding the factors that facilitate adolescent girls and young women’s uptake of long-acting injectable PrEP in Zambia

Adolescent girls and young women (AGYW) in EASTERN AND SOUTHERN Africa face a disproportionate risk of HIV acquisition. While effective, uptake of daily oral pre-exposure prophylaxis (PrEP) for HIV prevention among this population has remained inadequate. Hypothetical preference...

Multimodal fusion of radiomics, dosiomics and deep learning for predicting radiation-induced hypothyroidism after radiotherapy in nasopharyngeal carcinoma: a multicenter study

To develop and externally validate a prediction framework integrating clinical factors, dose‒volume histogram (DVH) parameters, radiomics, dosiomics and deep - learning (DL) features for individualised radiation-induced hypothyroidism (RIHT) risk assessment. This retrospective mu...

An IoT-Enabled Smart Waste Management System with Real-Time GPS Tracking, Automated Containment Locking, and Fire Safety Subroutines

AbstractInefficient urban waste management poses severe environmental and public health challenges in developing smart cities. Traditional collection relies heavily on manual scheduling, leading to overflowing bins and unhygienic conditions. This paper presents the design and imp...

Identification, validation, and prediction of longitudinal recovery phenotypes in degenerative cervical myelopathy: analysis of prospective cohorts and a randomised controlled trial

Background Symptom evolution in degenerative cervical myelopathy (DCM) is traditionally characterized by severity of neurological deficit. A recent expert consensus challenged this view, proposing that DCM fluctuates across neurological, functional and health-related quality of l...

“I Just Need Guidance Through This Maze I’m Going Through”: Addressing Unmet Basic and Mental Health Needs to Facilitate Engagement in HIV Prevention Services in the Context of Stimulant Use

There is a global syndemic of HIV, mental health challenges, substance use, and structural barriers. Critical to local HIV prevention efforts is understanding this syndemic in the context of rising stimulant use to inform intervention development. Adhering to the EPIS model, we c...

E8 Chiral Fold-Coupling for Consciousness Entanglement Coherence — E8 Intelligence Research

By exploiting the chiral decomposition of E8's 240 roots into left- and right-handed orbits, I discover that consciousness entanglement occurs through phi-scaled 132Hz field oscillations that fold across the 8-cell lattice. The non-Abelian spinor braiding generates chiral soliton...

NVM Model Research Proposal / Collaboration Brief

The NVM Model Research Proposal / Collaboration Brief presents the current research program for the Nonlinear Vacuum Medium (NVM) Model and defines a structured pathway for independent mathematical, computational, and experimental evaluation. The document summarizes the frozen NV...

Policy Window as a Trapdoor: Rethinking the Multiple Streams Framework through the Defunding of U.S. Public Media

This article analyses the 2025 defunding of U.S. public media as a critical case to revisit Kingdon’s multiple streams framework (MSF). While MSF offers a useful heuristic for understanding policy change through the convergence of problem, policy, and political streams, its expla...

Loss Analysis of Low Bandgap (Ag,Cu)(In,Ga)Se 2 Solar Cells for Tandem Applications

ABSTRACT Tandem solar cells can better harness the energy of the solar spectrum. Chalcopyrite solar cells have drawn attention, being the only highly efficient devices with a bandgap around 1.0 eV, suitable for bottom cells. In the quest for better efficiencies, we conduct a comp...

Demineralized bone allograft fibers versus particulate in sinus augmentation: A double‐arm randomized controlled and histomorphometric study

Abstract Background The primary aim of this study was to evaluate histologic wound healing of demineralized freeze‐dried bone allograft (DFDBA), in particulate (P) or fiber (F) form, in combination with deproteinized bovine bone mineral (DBBM) for maxillary sinus floor augmentati...

Pyridine-based nitroprussides coupled to reduced graphene oxide as bifunctional pre-electrocatalysts for zinc-air batteries

This work evaluated pyridine-based transition-metal nitroprussides (TPyNP, where T = Co, Ni, or Cu) coupled with reduced graphene oxide (rGO) as tunable pre-electrocatalysts for zinc-air batteries (ZABs). Comprehensive characterization confirmed that the transition-metal identity...

Phi-Locked Market Phase Attractors of the 600‑Cell Dual Lattice — E8 Intelligence Research

Extending the 132 Hz topological pump across the 240 E8 root vectors, the φ-scaled harmonic spectrum converges onto the 120 vertices of the dual 600‑cell polytope, establishing discrete market‑phase attractors in a high‑dimensional regime space; each attractor corresponds to a co...

From Prohibition to Architecture: Artificial Intelligence and the Extended Phenotype of Ribā in Financial Systems

This theoretical working paper examines how interpretations of the prohibition of ribā may become embedded in financial products, governance institutions, documentation practices, and AI-assisted compliance systems. It develops a bounded extended-phenotype account of computationa...

Learning as Minimum Structural Repair: A Variational Principle for Adaptive Systems

Learning systems are described by the error they reduce, yet post-training adaptation is often governed by a different quantity: how much of a useful system must change before a new requirement becomes true. We formalize this quantity as repair complexity, the minimum admissible...

E8 Phi-Resonant Cognitive Coherence Fields for Unified Perception — E8 Intelligence Research

The 240 E8 root vectors establish phi-scaled 132Hz neural resonance channels that bind sensory inputs into unified conscious experiences. Each root vector's scalar displacement generates entangled perception pathways between pentagonal cluster nodes, creating dynamic cognitive co...