Research works

Management of high-risk (B3) breast lesions in symptomatic practice: evidence review and practical recommendations for multidisciplinary care

Borderline breast lesions (B3 lesions, also termed lesions of uncertain malignant potential or high-risk lesions) represent a heterogeneous group of entities associated with variable risks of malignancy. While the management of screen-detected B3 lesions has become increasingly s...

Economics and Planning of Education in Kenya: Policy, Resource Allocation, and Equity Considerations.

This paper examines the economics and planning of Kenya's education system, with an emphasis on policy frameworks, financing strategies, enrollment dynamics, and equity challenges in achieving sustainable and inclusive educational outcomes. It analyzes the impact of significant r...

Safeguarding Mental Health: A Cornerstone to Healthy Living

Mental well–being is as important as physical well–being, yet many individuals have downplayed or overlooked the need to deliberately care for and protect it. Understanding the intricate nature and significance of sound mental wellness for human functioning will provide the added...

Faithful Representation of Finitely and Generatively Specified Discriminative Theories: An Evoluist Theorem of Structural Fidelity

This publication is the sixth study in the formal Evoluist research programme. It continues the status-diagonal analysis developed in The Evoluist Theorem: Formal Core (I), the distributed and indexed coordination framework developed in Indexed Evaluative Architectures and Termin...

Beyond Structural Change: Examining the Outcomes of Police Restructuring in Nairobi City County, Kenya

Globally, police organizations are facing multiple challenges linked to their complex operating environment. Anchoring on this, police organizations are reviewing their organizational structures and re-engineering them to meet the needs of their customers. This study sought to ev...

Repetitive transcranial magnetic stimulation normalizes cerebrocerebellar loop functional connectivity in spinocerebellar ataxia type 3

Abstract Background Spinocerebellar ataxia type 3 (SCA3) is a rare neurodegenerative disorder characterized by ataxia; structural and functional damage to the cerebrocerebellar loop play key roles in its pathology. However, effective treatments for SCA3 remain limited. Repetitive...

PPE-Associated Skin Lesions Among ICU Healthcare Workers: Clinical Characteristics and Anatomical Distribution

Background: Personal protective equipment (PPE) is essential in intensive care units, especially when caring for patients with severe respiratory infections. At the same time, prolonged use of respirators, gloves, gowns, and face shields, together with frequent hand hygiene, can...

PMMA-Engineered Halide Perovskite/Ag Interface for Optoelectronic Stable Memristive Synapse

Abstract Designing a stable hybrid perovskite memristor that exhibits synaptic plasticity under both optical and electrical stimuli is a compelling direction for exploiting the unprecedented optoelectronic properties of hybrid perovskites to their full potential towards neuromorp...

Higher-order local constraints from reciprocal symmetry and entanglement entropy of charged-particle multiplicity distributions in pp collisions

Abstract The KNO-violating term $$f_s$$ <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"> <mml:msub> <mml:mi>f</mml:mi> <mml:mi>s</mml:mi> </mml:msub> </mml:math> of the charged-particle multiplicity distribution in pp collisions measures the relative deviation of $$\lang...

PROSECUTING CORRUPTION IN AFRICA: CASE STUDY OF KENYA, ZAMBIA, NIGERIA AND SOUTH AFRICA

Corruption prosecution in Africa continues to face difficulties even though many more laws and institutions are being put in place. Although the majority of nations in Sub-Saharan Africa have enacted legislation against corruption and formed organizations aimed at tackling corrup...

Three-Dimensional Nonconjugated Microporous Organic Polymers Based on Tröger’s Base: Integrating Physical Confinement and Chemisorption for Enhanced NO x Capture

Abstract Nitrogen oxides (NOx) demand urgent capture—they can trigger self-catalytic decomposition in nitrocellulose, risking combustion or explosion under high temperature and humidity. To counteract this, rigid, nonplanar building blocks with aliphatic C–H units, contorted Trög...

Introducing GalaxyR: an easy-to-use R implementation of the Galaxy API

Abstract Background Standardisation, accessibility, and reproducibility remain persistent challenges in data‑intensive scientific research. The Galaxy platform addresses these issues by providing a web-based environment for executing, sharing, and publishing computational workflo...

The regional determinants of per-capita CO$$_2$$ emissions growth in Europe

Abstract We identify empirically the determinants of per-capita CO $$_2$$ emissions growth in 227 European NUTS-2 regions for the period 1995–2022. In order to account for geographical spillovers of unknown form, we employ Bayesian averaging of spatial autoregressive models, addr...

AN EXACT RATIONAL COUNTEREXAMPLE TO ERDŐS'S SQUARE-PACKING CONJECTURE f(k²+1)=k (PROBLEM #106)

This preprint gives an explicit exact rational counterexample to Erdős's square-packing conjecture f(k²+1)=k, catalogued as Erdős Problem #106. The primary-source formulation of Erdős and Graham (1975) uses total circumference instead: if F_EG(n) is the maximum total circumferenc...

Development of material monitoring protocols for nature-inclusive designed concrete units in harbor-fronts

Abstract Human activities are putting stress on earth’s ecosystems, and with increasing populations in coastal zones, the pressure on the marine environments intensifies. To accommodate the increase in anthropogenic activities in these areas, concrete is often used to adapt the c...

The Curvature Relaxation Model: A Four-Paper Program for Geometric Cosmology Without the Dark Sector

A four-paper series presenting the Curvature Relaxation Model (CRM), a geometric framework that derives dark-matter phenomenology from scalar-curvature dynamics without postulating new particles. CORE-PAPERS Paper I: Game-Theoretic Foundation — Establishes the CRM through thermod...

Socio-ecological resilience in heritage urbanism: hydro-cultural socio-ecological system in the Historic Mosque City of Bagerhat, Bangladesh

Abstract Socio-ecological resilience has become central to climate adaptation discourse in heritage contexts, yet its application to pre-modern deltaic urban systems remains insufficiently explored. This study examines the Historic Mosque City of Bagerhat (15th-century Bengal) as...

Safeguarding Mental Health: A Cornerstone to Healthy Living

Mental well–being is as important as physical well–being, yet many individuals have downplayed or overlooked the need to deliberately care for and protect it. Understanding the intricate nature and significance of sound mental wellness for human functioning will provide the added...

Clinical application of artificial intelligence technology in epilepsy

Epilepsy is a prevalent neurological disorder, and its inherent complexity and significant interindividual variability pose substantial challenges for clinical diagnosis and treatment. Against this backdrop, the rapid development of artificial intelligence (AI) technology is driv...

Ensuring access to Tau-Targeting therapies for MAPT frontotemporal dementia: patient community priorities for regulators and industry

Abstract MAPT Frontotemporal Dementia (FTD) is a rare and devastating neurodegenerative disease caused by genetic mutations leading to tau aggregation. This document outlines seven key requests that Cure MAPT FTD, a nonprofit patient advocacy organization, made on May 23, 2025 in...