Mapping Cellular Senescence, Cellular Plasticity, and Alveolar Niche Heterogeneity in Human Lung Development

Abstract

This repository contains the code, workflows, and source files used for the analyses presented in the manuscript. Contents Preprocessing and integration of pediatric lung snRNA-seq datasets Harmony integration and Azimuth annotation workflows Cell proportion analyses Differential gene expression analyses Gene ontology and pathway enrichment analyses Heatmap generation Feature plots and visualization scripts Pseudotime trajectory analyses Molecular clock and senescence-related analyses The repository is organized by figure to facilitate reproducibility and code availability.