Biochemistry, Genetics and Molecular Biology · Molecular Biology

Congenital heart defects research

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Abstract editorial illustration accompanying the article: Two-compound mix pushed adult heart cells toward an embryonic-like state

Two-compound mix pushed adult heart cells toward an embryonic-like state

A treatment containing phenylephrine hydrochloride and harmine pushed adult heart-muscle cells toward an embryonic-like state and increased their proliferation in laboratory and in vivo experiments. The findings come from experimental models, not human trials, and the abstract does not establish whether the approach restores heart function or is safe in people.

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