University of Rochester

Longitudinal exploration of auditory sensory-perceptual processing in CLN3 disease (Juvenile Neuronal Ceroid Lipofuscinosis (Batten disease)): A high-density auditory evoked potential (AEP) study

Background: There is currently limited information about sensory and perceptual abilities across the progression of CLN3 disease (Juvenile Neuronal Ceroid Lipofuscinosis; Batten disease), a recessively inherited lysosomal storage disorder and a leading cause of childhood neurodeg...

Comparison of lower urinary tract symptoms between incontinent males and females: An analysis of AUASS and its subdomains

Introduction and objectives: The American Urological Association Symptom Score (AUASS) assesses lower urinary tract symptoms (LUTS), primarily in males with benign prostatic hyperplasia. Though validated in females, differences remain understudied. This study compares AUASS in in...

Continuous Publishing as Next Step in Continuous Improvement at Hospital Pediatrics

We are excited to announce that Hospital Pediatrics has moved to a continuous publishing model. What is continuous publishing? It is a relatively new model in which articles are published shortly after acceptance versus the historical model of publication occurring when space was...

Postoperative Interventions and Cost Associated With Disposition After Tonsil and Adenoidectomy

OBJECTIVE To evaluate postoperative disposition and resource use among patients admitted to the inpatient unit or pediatric intensive care unit (PICU) following tonsillectomy, adenoidectomy, and tonsillectomy/adenoidectomy (T/A). PATIENTS AND METHODS This retrospective cohort stu...

Influenceof Chalcogen Bonding on Lattice Dynamicsin Isostructural Molecular Solids

Abstract Solid-state lattice dynamics can significantly impact the expression of material properties in crystalline molecular materials, complicating crystal engineering efforts that approach materials design from a primarily static structural picture. While noncovalent interacti...

Late Adolescents' Beliefs About Parental Monitoring of Online and Routine Behavior

INTRODUCTION: Despite the amount of time adolescents spend online, relatively little research has focused on parental monitoring of adolescents' online behavior. The present study examined late adolescents' retrospective evaluations of parental rules and their right to know about...

Distinct Sex-Specific Characteristics of Apoe Deficient and Ldlr Deficient Mice in Atherosclerosis: Implications for Model Selection and Therapy Development

The progression of cardiovascular disease shows significant sexual dimorphism: although females generally develop the disease later in life, they exhibit a higher age-related incidence than males. While current studies have separately reported sex differences in atherosclerotic d...

Mating strategies in Caenorhabditis elegans populations are determined by male developmental history.

Mating strategies, whether sexual or asexual, confer unique costs and benefits to populations and species that facilitate evolutionary processes. In wild isolates of Caenorhabditis elegans, mating strategies are dependent on developmental history. Outcrossing significantly increa...

Long‐term prediction of epilepsy following traumatic brain injury among veterans using routine clinical data

OBJECTIVE: Despite elevated risk for epilepsy following traumatic brain injury (TBI), there are limited tools to assess epilepsy risk following TBI using routine clinical data. The objective of this study was to develop and validate a machine learning approach to predict the onse...

Reach of Palliative Care in Parkinson Disease: Progress and Gaps After a National Team-Based Implementation Project.

BACKGROUND AND OBJECTIVES: The value of palliative care (PC) is increasingly recognized in the care of people with Parkinson disease (PWP) and their carepartners. While clinical trials demonstrate PC improves quality of life for PWP and carepartners, little is known about the imp...

UNC5B regulates epithelial-to-mesenchymal transition through a SRC-ZEB1 signaling axis to facilitate pancreatic cancer metastasis

Metastatic dissemination is the principal cause of death in pancreatic ductal adenocarcinoma (PDAC), yet the molecular determinants that enable this process remain poorly understood. Here, we identify the axon guidance receptor UNC5B as a central regulator of PDAC metastasis. Usi...

Enhancing EFL Oral Proficiency through Video-Based Tasks Implemented in a Flipped Classroom

This study investigates patterns associated with the integration of video-based tasks within a flipped classroom model grounded in task-based language teaching (TBLT) in relation to English as a foreign language (EFL) learners’ speaking fluency, accuracy, and engagement. TBLT emp...