The Orexin System—A Key Component of Sleep Regulatory Networks and Involvement in Narcolepsy
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Abstract
In this Perspective, 2026 Albert Lasker Basic Medical Research Award winners Emmanuel Mignot, MD, PhD, and Masashi Yanagisawa, MD, PhD, discuss their identification of the brain peptide orexin and how it relates to sleep, specifically orexin deficiency and narcolepsy.
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Authors: Emmanuel Mignot, Masashi Yanagisawa
Institutions: University of Tsukuba, Stanford University, Palo Alto University