Biochemistry, Genetics and Molecular Biology · Biophysics

Advanced Fluorescence Microscopy Techniques

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Abstract editorial illustration accompanying the article: A new way to map cell detail inside thick samples needs no added labels

A new way to map cell detail inside thick samples needs no added labels

Researchers developed an imaging approach that reconstructs label-free, three-dimensional subcellular detail in thick, highly scattering biological samples. Tests on model samples and biological specimens showed that specific measurement and calculation choices produced high-quality maps of the samples’ internal optical properties.

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