Zhejiang University

Performance Optimization of Novel Laser Hybrid Ultrasonic Vibration Assisted Micro Milling for Inconel 718

Miniaturization drives advanced manufacturing essential for next-generation systems using superalloys in aerospace, biomedical and microelectronics. Hybrid machining combines distinct processes to harness their individual strengths and overcome limitations. This experimental rese...

ACE2-PNA conjugates exploit viral endocytosis for targeted intracellular delivery and exhibit dual antiviral efficacy against SARS-CoV-2

The COVID-19 pandemic and its protracted consequences underscore the urgent need for more effective antiviral strategies. Current antiviral strategies face a persistent challenge achieving sufficient viral suppression while minimizing off-target toxicity, particularly against suc...

Organizing Large GTPase Atlastin‐Mediated Membrane Fusion by Programmable DNA Origami Platforms

ABSTRACT In eukaryotic cells, the endoplasmic reticulum (ER) utilizes membrane fusion to form interconnected networks. GTP hydrolysis‐triggered conformational changes in ER‐anchored atlastins (ATLs) have been shown to be responsible for this process, which is facilitated by the a...

Vision-Based Counting of Horticultural Seeds Using ViT-UNet Density Regression for Post-Harvest Quality Assessment

Reliable counting of horticultural seeds is important for seed grading, batch consistency assessment, packaging, sowing-rate control, and post-harvest quality evaluation. Manual counting is labor-intensive, whereas conventional image-processing methods can be sensitive to seed ad...

Microbiota Dynamics and Listeria monocytogenes Inhibition in Vacuum-Packed Brown Bear Meat Treated with β-Cyclodextrin-Encapsulated Essential Oil

Abstract This study evaluated the microbiological quality and microbiota dynamics of brown bear ( Ursus arctos ) meat treated with β-cyclodextrin inclusion complexes of Origanum vulgare essential oil (OVEO/β-CD) and Illicium verum essential oil (IVEO/β-CD) during 21 days of refri...

Sexual dimorphism in root exudation mediates belowground neighbor recognition and shapes rhizosphere soil microbial assembly

Summary Sexual dimorphism in physiological traits is a hallmark of dioecious plants, yet whether these differences extend belowground to mediate neighbor recognition and rhizosphere microbiome assembly remains largely unexplored. Using split‐root experiments, 13 C‐pulse labeling,...

Renovation dimensions and residents’ subjective well-being in old residential neighbourhoods: a structural equation modeling study in Hangzhou, China

Abstract Aligned with the global agenda for sustainable urban regeneration, this study examines how different dimensions of old residential community renovation relate to residents’ subjective well-being (SWB) in urban China. SWB is defined as residents’ situated evaluation of co...

Metal‐Half‐Salen Chemistry for One‐Pot Mineralization on Hydrophobic Polymer Membranes

ABSTRACT Organic–inorganic composite membranes combine the advantages of polymers and inorganic materials, yet their fabrication remains challenging due to poor interfacial compatibility, especially on chemically inert hydrophobic substrates. Here, we report a one‐pot strategy to...

Defect‐Rich Ir Single‐Atom/NiMnO x Catalyst: From Surface Reconstruction to Practical PEM Electrolysis

ABSTRACT Developing highly active and durable catalysts for the acidic oxygen evolution reaction (OER) remains a key challenge for proton exchange membrane water electrolysis (PEMWE). Herein, we report an efficient OER catalyst constructed via a low‐temperature calcination‐hydrot...

The proletarianized professoriate: Digital narcissism and affective exhaustion on academic social networks

Contemporary academic life is increasingly mediated by digital platforms that promise visibility, connection, and faster circulation of research. This article argues that the affective exhaustion associated with these conditions should not be treated only as a problem of individu...

Integrated 1D‐LC‐HRMS and Heart‐Cutting 2D‐LC–MS for Impurity Profiling and Chiral Separation of Mitiglinide Drug Substance

ABSTRACT Rationale The comprehensive quality control of chiral pharmaceuticals like mitiglinide necessitates simultaneous assessment of chemical impurities and enantiomeric purity, yet conventional workflows address these separately, leading to inefficiency. This study develops a...

Associations of dietary inflammatory index with respiratory tract infections among US adults and the mediating roles of systemic inflammation markers

Respiratory tract infections (RTIs) remain a major public health burden among adults, with substantial interindividual heterogeneity in susceptibility. Chronic low-grade systemic inflammation has been proposed as an important host-related determinant of infection risk, and the di...

Bioactive composition and pharmacology of red wine, beer, and Huangjiu (Chinese rice wine): a review

Red wine, beer, and Huangjiu (Chinese rice wine) are widely consumed fermented alcoholic beverages whose compositions and health effects have attracted considerable interest. Current evidence indicates that fermentation endows these beverages with diverse bioactive compounds such...

Unified Friction Factor Model for Dune Beds from High to Low Submergence

Abstract Accurate prediction of flow resistance in dune-bed streams is critical for river engineering and flood management. Traditional methods, which rely on empirically partitioning total shear stress into skin and form drag, often fail under low-submergence conditions where th...

All-Optically Controlled Memristive Reservoir Computing Capable of Bipolar and Parallel Coding

Physical reservoir computing (RC) utilizes intrinsic dynamics of physical systems for efficient data processing. Emerging optoelectronic RC platforms merge the benefits of electronic and photonic computation. However, conventional designs are constrained by the unipolar photoresp...

Genetic screening identifies WNT5A/RYK as a determinant of extracellular vesicle fate

Extracellular vesicles (EVs) are natural mediators of intercellular communication through the transfer of cytoplasmic material from donor to recipient cells. The molecular mechanisms governing EV uptake and cargo delivery in recipient cells remain largely elusive. To address this...