University of Ulsan

Bromide–Borate Coupling Enables Selective Electrochemical Oxidation of Glycerol to Dihydroxyacetone

ABSTRACT Selective electrochemical valorization of biodiesel‐derived glycerol is challenged by competing oxidation pathways that generate complex product mixtures. Here, we report a bromide–borate‐mediated indirect glycerol electrooxidation for selective dihydroxyacetone (DHA) pr...

Clinical Outcomes of Switching from Prostaglandin Analogs to Omidenepag Isopropyl in Primary Open-Angle Glaucoma and Glaucoma Suspect Patients with Prostaglandin-Associated Periorbitopathy: A Prospective, Multicenter Study

Background/Objectives: Prostaglandin-associated periorbitopathy (PAP) is a common treatment-related burden of prostaglandin analog (PGA) therapy that may compromise long-term glaucoma management. This study evaluated improvement in PAP and changes in intraocular pressure (IOP) af...

Screening strategies for the early detection of non-cardia gastric cancer in low- to moderate-prevalence regions: Asia-Pacific gastroesophageal cancer congress consensus 2026

Abstract Background Gastric cancer (GC) remains a major global health burden, and early detection is essential for improving patient outcomes. Although GC screening has been widely implemented in East Asian countries with a high disease burden, the optimal screening strategy for...

An Explainable Transfer Learning Framework Based on Acoustic Spectral Portraits for Pipeline Leak Diagnosis Across Composite Operating and Acquisition Conditions

This study proposes an explainable and lightweight pipeline leak-diagnosis framework based on a leak-oriented Acoustic Spectral Portrait (ASP) processing pipeline and transfer learning. The ASP processing pipeline converts one-dimensional acoustic emission signals into compact tw...

Long-Term Outcomes According to a Device-Assisted Enteroscopy Strategy after Capsule Endoscopy in Patients with Small Bowel Bleeding: A Nationwide Population-Based Cohort Study

Background/Aims: Although the use of device-assisted enteroscopy (DAE) has increased, few large-scale studies have examined long-term outcomes focused on small bowel (SB) bleeding. We analyzed National Health Insurance Service data to evaluate the clinical utility of DAE in patie...

A Dual-Modal Hybrid Marker for Automatic Registration and Coordinate Hand-Over in C-Arm CT-Guided Spinal Navigation

An asymmetric hybrid registration frame (RF) integrates radiopaque and optical markers to automate computed tomography (CT) registration and coordinate hand-over to a dynamic reference frame (DRF). We compared automatic and manual fiducial selection using three fixed CT datasets...

Age-Stratified Median Effective Dose of a Continuous Remimazolam Maintenance Infusion for Moderate Sedation During Spinal Anesthesia: A Prospective Up-and-Down Dose-Finding Study

Background and Objectives: Remimazolam is an ultra-short-acting benzodiazepine suitable for continuous infusion; however, evidence regarding its maintenance infusion rate for moderate sedation during spinal anesthesia across age strata is limited. We aimed to estimate and compare...

Association of Estimated Arterial Stiffness with Collateral Status and Functional Outcome after Endovascular Thrombectomy: A Secondary Analysis of the OPTIMAL-BP Trial

PURPOSE: Estimated pulse wave velocity (ePWV) is a surrogate of arterial stiffness that may influence stroke outcomes and potentially affect collateral circulation. We examined the association of ePWV with collateral status and 3-month functional outcome after successful endovasc...

Lipid Burden and Efficacy of Preventive PCI of Vulnerable Atherosclerotic Coronary Plaques: Post Hoc Analysis From the PREVENT Trial

BACKGROUND: Preventive percutaneous coronary intervention (PCI) of non–flow-limiting lesions (fractional flow reserve >0.80) that are high-risk plaques has emerged as a potential strategy to reduce cardiac events. However, identifying which lesions derive the greatest benefit fro...

Mitochondria-targeted DZ-1-dihydroartemisinin conjugate induces Bax/Bak-independent apoptotic cell death in colorectal carcinoma cells

Artemisinin and its derivatives possess anti-malarial as well as anti-cancer properties against various malignancies. However, their clinical application as anti-cancer agents is limited by several factors, most notably a lack of tumor selectivity. To address this limitation, we...

Early Mitral Valve Surgery and Survival in Asymptomatic Severe Primary Mitral Regurgitation

Importance The optimal timing of mitral valve (MV) surgery in patients with asymptomatic severe primary mitral regurgitation (MR) remains uncertain because randomized clinical trials are lacking. Objective To evaluate the association of early MV surgery with long-term survival in...

Preoperative pulse rate variability and the hemodynamic response to tracheal intubation: a retrospective secondary analysis

Individual hemodynamic responses to tracheal intubation vary considerably. We examined whether preoperative pulse rate variability (PRV), a photoplethysmography-derived surrogate of heart rate variability, is associated with this response. In this retrospective secondary analysis...

Clinical Importance and Usefulness of Direct Targeting of the Ventral Intermediate Nucleus of the Thalamus Using Fluid and White Matter Suppression Imaging at 3T MRI

BACKGROUND AND OBJECTIVES: Stereotactic targeting of the ventral intermediate nucleus of the thalamus (Vim) in tremor surgery traditionally relies on indirect, atlas-based coordinates, whereas direct visualization of the Vim using advanced MRI sequences has the potential to impro...

A Physics-Guided Statistical Framework for Bearing Fault Diagnosis Under Unit Variability and Rotational Speed Uncertainty

Reliable bearing fault diagnosis must differentiate between defects and normal-operation-condition variation. The predictor must remain accurate when shaft speed is uncertain. Conventional accuracy-driven models often ignore false-positive rates and fail to accurately locate faul...

2025 Korean Guidelines for Cardiopulmonary Resuscitation: Part 9. Neonatal resuscitation: a secondary publication

The 2025 Korean Guidelines for Cardiopulmonary Resuscitation provide updated, evidence-based recommendations to optimize the transition from intrauterine to extrauterine life. While approximately 85% of term newborns initiate spontaneous breathing independently, timely interventi...

Consensus recommendations for neurofibromatosis type 1 management in Asia Pacific

Neurofibromatosis type 1 (NF1) is a complex multisystem disorder requiring coordinated multidisciplinary care. This study aimed to develop consensus recommendations for NF1 management in the Asia-Pacific region. A modified Delphi process involving two survey rounds and a virtual...

Stereotactic body radiation therapy for hepatocellular carcinoma: 2026 expert consensus-based practical recommendation of the Korean Liver Cancer Association

Stereotactic body radiation therapy (SBRT) is a noninvasive, high-precision radiation technique that delivers a high dose to the tumor in a limited number of fractions, typically five or fewer, and is increasingly used as a curative-intent option for hepatocellular carcinoma (HCC...

Combined Gemcitabine and Nab-Paclitaxel Treatment Restores Gut Microbiota Homeostasis in an Orthotopic Pancreatic Ductal Adenocarcinoma Mouse Model

PurposeAlthough chemotherapy can disrupt homeostasis of gut microbiota, the role of chemotherapy affecting in gut microbiota of pancreatic ductal adenocarcinoma (PDAC) is unclear. Materials and MethodsWe evaluated whether chemotherapy could alter the integrity of gut microbiota o...

Fasting Duration and Differences Across Routine Laboratory Tests

Importance Fasting before blood collection is widely practiced to reduce preanalytical variability, yet whether fasting-related differences are clinically meaningful across a broad panel of routine analytes has not been systematically evaluated using clinical data. Objective To e...

Anaphylaxis with Paradoxical Hypertension During Platelet Transfusion: A Case Report

with epinephrine [2].Nevertheless, atypical presentations of anaphylaxis without hypotension have been reported, including cases with normal or elevated blood pressure [3,4].Such presentations may delay recognition or lead to misdiagnosis, particularly in transfusion settings whe...