University of Turku

Regional Expression Profiles of Artemin Protein and GFRα3 mRNA During Postnatal Brain Development in Rats

Artemin, a member of the glial cell line-derived neurotrophic factor family, plays important roles in neuronal processes through GDNF family receptor alpha 3 (GFRα3)-mediated signaling. However, the expression patterns of Artemin and GFRα3 during normal postnatal brain developmen...

Haunting data: Mental health, data-hacking and digital temporalities

This article maps the experiences of victims of the Vastaamo psychotherapy centre data hack by analysing their stories through a lens provided by the digital hauntology framework. The article views the data-hacking incident as a form of terror that continues to weigh on the victi...

Identifying drugs associated with Alzheimer's disease risk using machine learning-assisted signal detection

Background Several Alzheimer's disease (AD) clinical trials currently focus on drug repurposing. Machine learning (ML)-based pharmacoepidemiological approaches may help identify candidate drugs for trials. Objective We applied an ML-based signal detection method to identify drugs...

Validation of diagnostic artificial intelligence models for prostate pathology in a Middle Eastern cohort

Abstract Artificial intelligence (AI) for pathology is accelerating cancer diagnostics. For global adoption, studies in currently under-represented populations – where the potential gains from AI may also be greatest – are needed. We present the first external validation study in...

Effect of sonication on European and Peruvian lupin flours: impact on the technological quality of gluten‐free breads and as a partial substitute for wheat

BACKGROUND: A widely cultivated pulse, lupin, has garnered interest for its beneficial nutritional properties, especially for baking applications. The harmful alkaloid content and poor functional properties of lupin limit its wider use. Sonication is an ecofriendly technology use...

The Diffusion of Cohabitation Among Immigrants in Europe: The Role of the National Cohabitation Context

Abstract Immigrants and their descendants constitute an increasing share of European populations, yet research on how immigrant background shapes the cohabitation experience remains limited. This study investigates how generational status at the individual level and national cont...

Thyroid carcinoma in Graves’ disease: a retrospective analysis of prevalence, histological subtypes, and clinical predictors

Graves’ disease (GD) is an autoimmune cause of hyperthyroidism frequently associated with thyroid nodularity. However, whether GD confers an increased risk of differentiated thyroid carcinoma (DTC) compared with euthyroid populations remains uncertain, and reliable clinical predi...

Digital solutions for tackling mental health in cancer patients and their families: The ALTHEA project

Despite advances in cancer treatment, the growing global cancer burden underscores the need for comprehensive and supportive care to address the needs of patients and their families. However, access to psycho-oncological support remains often limited across healthcare systems. Th...

Circulating Pro-Resolving Mediators Maresin-1 and Maresin-2 and Adipolin/CTRP12 in Adults with Atopic Dermatitis: A Case–Control Study

Background and Objectives: Defective resolution of inflammation may contribute to chronicity in atopic dermatitis (AD). Maresin-1 (MaR1) and Maresin-2 (MaR2) are docosahexaenoic acid-derived specialised pro-resolving mediators, and adipolin/C1q/TNF-related protein 12 (CTRP12) is...

Digital communication and occupational well-being in 25 European countries

Abstract This paper examines the association between digital communication at work and employee well-being, moderated by occupational status and the fulfillment of basic psychological needs. Two studies were conducted to investigate these relationships. Study 1 utilized data from...

Advances in 3D Bioprinting for Breast Cancer Modeling: Tumor Microenvironment, Metastasis, and Drug Screening

The tumor microenvironment (TME) is a complex and heterogeneous milieu encompassing biological and biochemical events and diverse physical, chemical, and mechanical interactions between tumor and stromal cells. This heterogeneity plays a pivotal role in regulating tumor progressi...

Landscape composition and photoperiod shape differences in space use and hunting behaviour between boreal and Alpine pygmy owl populations

Abstract Context Investigating how habitat specialists express population-level differences in habitat preferences and movement behaviour across contrasting landscapes and abiotic environments allows us to distinguish patterns that are consistent across populations from those tha...

The effect of women’s e-health literacy on their knowledge, attitudes, and behaviors regarding vulvar cancer and self-examination: a cross-sectional study

This study aimed to investigate the impact of women’s e-health literacy on their knowledge, attitudes, and behaviors regarding vulvar cancer and vulvar self-examination. This study was a community-based cross-sectional. This study was performed between November 7, 2024, and Janua...

Device-measured physical activity and sedentary behavior during office versus remote workdays among hybrid workers

OBJECTIVES: Daily sedentary time (SED) has been found to be higher during remote compared to office workdays, but current evidence mostly relies on studies from COVID-19 pandemic times. This study aimed to compare device-measured physical activity (PA) and SED between office and...

The Relationship Between Registered Population Size and Chronic Disease Management Performance Among Family Physicians

Aim: The increasing prevalence of chronic diseases requires systematic monitoring in primary care. This study examined the association between registered panel size and chronic disease management performance among family physicians and identified associated factors. Methods: In t...

A Hybrid Deep Learning Approach for Early Detection of Wildfires Using Transformer Models and Feature Fusion Techniques

Natural disasters, particularly wildfires, pose a serious threat to ecosystems, human lives, and infrastructure, making rapid and accurate fire detection essential for effective disaster management. Despite recent advances in deep learning-based wildfire detection, conventional C...

From Norms to Behavior: Examining the Mechanisms of Change in a Social Norms Anti-Bullying Intervention Among Early Adolescents

Social norm interventions offer a promising approach to bullying prevention, yet the mechanisms through which they operate remain unclear. Using a parallel mediation structural equation model, this study examined potential mediators of a classroom-based social norms intervention...

Asymmetric Structure‐Driven Functional Synergy: A Multistimuli‐Activated Janus Nanomotor for Self‐Amplifying NO Cascade Therapy

ABSTRACT Nitric oxide (NO)‐based cancer therapy is fundamentally limited by poor intratumoral penetration of exogenous donors and their inability to sustain localized relevant flux. Here, a multistimuli‐activated Janus nanomotor was developed to interconnect nonenzymatic and enzy...

Eudynamic bioethics

Abstract A woman’s chronic pain is controlled to a stable score, yet her sleep, her work, her singing, and her partnership have narrowed around her condition. Each clinical decision was defensible; what failed is the existential composition around them. This article proposes eudy...

Epidemiological associations between neurodegeneration and cancer – time to refine our research approach

Cancer and neurodegenerative diseases are devastating aging-related disorders. Epidemiological data suggest a general inverse risk association between them, the mechanisms of which might provide new avenues for developing treatments and prevention strategies. In addition to this...