University of Rome Tor Vergata

Assessing the Climate and Habitability of Tidally Locked Rocky Exoplanets

Tidally locked exoplanets orbiting M dwarf stars are prime targets in the search for habitable worlds, yet their complex climate dynamics challenge conventional models of habitability. We homogeneously estimated the liquid–water habitability of exoplanets with the highest up-to-d...

Cuproptosis: an emerging member of the immunogenic cell death family

Cell death was long considered the terminal consequence of cellular stress or damage, and distinct cell death modalities were classified according to their molecular execution mechanisms rather than their immunological impact [ 1 , 2 ]. This reductionist view has progressively be...

Adult attachment, death anxiety, representation of death, and depression, anxiety, obsessive-compulsive, and somatic symptoms in early emerging adulthood: a moderated mediation model

Death anxiety has been increasingly recognized as a transdiagnostic factor associated with a wide range of internalizing symptoms, yet the psychological mechanisms linking existential concerns to psychopathology remain incompletely understood. Drawing on attachment theory and exi...

Effectiveness of Therapeutic Sport Footwear in Prevention of Ulcer Recurrence in Persons with Diabetic Foot Disease

Recurrence of diabetic foot ulcer (DFU) remains a major clinical challenge in patients with diabetes. Therapeutic footwear is a cornerstone of secondary prevention as it reduces plantar pressure and mechanical stress. However, most available evidence focuses on traditional orthop...

Localized brain delivery of drugs via focused ultrasound-responsive bi-layer nanobubbles

Focused ultrasound (FUS) in combination with micro- or nanobubbles is a promising strategy for transiently and non-invasively opening the blood-brain barrier (BBB) to enable targeted drug delivery to the brain. Here, we report a FUS-responsive delivery system using bi-layer nanob...

Beyond Weight Loss: A Comprehensive Review of Integrated Pharmacotherapy and Metabolic Bariatric Surgery in Endometrial Cancer Care

Backgroundand Objectives: Endometrial cancer ranks among the most prevalent gynecologic malignancies in high-income countries, with increasing incidence and mortality driven by the global obesity epidemic. Evidence suggests that women with early-stage disease face a greater risk...

Real‐world outcomes of venetoclax plus hypomethylating agents in unfit acute myeloid leukaemia: Results of the GIMEMA AML2320 trial

Summary Venetoclax (VEN) plus hypomethylating agents (HMAs) represents the standard of care for newly diagnosed acute myeloid leukaemia (AML) patients unfit for intensive chemotherapy, but prospective real‐world observational data outside randomized clinical trials remain limited...

Sulfur Dioxide Disproportionation by Magnesium Sulfite as Intermediate

Solar-assisted thermochemical cycles can convert intermittent solar energy into storable chemical fuels. Within the European SULPHURREAL project, elemental sulfur is investigated as a long-term energy-storage medium in a cycle based on H2SO4, S, and SO2. This work investigates an...

Fluid–Structure Interaction Modeling of Sloshing Dynamics with Flexible Baffles

This study presents a comprehensive analysis of sloshing dynamics in rectangular tanks equipped with flexible antisloshing devices (ASDs), focusing on how varying baffle elasticity influences fluid–structure interaction (FSI). Three configurations, differing in baffle submergence...

Visible-Light-DrivenPorphyrin/ZnO Nanohybrids forUltrasensitive Room-Temperature Triethylamine Sensing

Abstract Real-time monitoring of toxic triethylamine (TEA) at room temperature remains a significant challenge for metal oxide chemiresistors due to their typically high-power consumption and thermal requirements. This work presents a highly responsive, visible-light-activated ga...

Extra-Endocrine Features in Infancy as Early Clues to MEN2B

Multiple endocrine neoplasia type 2B (MEN2B) is a rare autosomal-dominant cancer predisposition syndrome in which prognosis is strongly influenced by the stage of medullary thyroid carcinoma at diagnosis. Virtually all affected children exhibit 1 or more extra-endocrine features...

Serum Angiopoietin-1 and Angiopoietin-2 as Biomarkers of Pulmonary Hemodynamic Burden in COPD-Associated Pulmonary Hypertension: A Cross-Sectional Study

Purpose: Pulmonary hypertension (PH) is a serious complication of COPD associated with worse outcomes. Reliable circulating biomarkers of pulmonary vascular involvement are lacking. Angiopoietin-1 (ANGP-1) and angiopoietin-2 (ANGP-2) regulate endothelial homeostasis, but their re...

Engineered PEA-producing Lactobacillus paracasei F19 prevents colitis-associated colorectal cancer in mice by modulating inflammatory–angiogenic signaling and beneficially reshapes gut microbiota composition

Colitis-associated colorectal cancer (CAC) arises from the interplay between chronic inflammation, epithelial dysregulation, angiogenesis, and microbiota alterations. Palmitoylethanolamide (PEA) is an endogenous lipid mediator with anti-inflammatory and anti-angiogenic properties...

Multimodal radiomic and foundation-model MRI features converge on basal ganglia patterns in Parkinson’s motor subtypes

Parkinson’s disease (PD) comprises heterogeneous motor phenotypes, most prominently tremor-dominant (TD) and postural instability/gait difficulty (PIGD), which differ in progression, disability burden, and therapeutic response. Despite standardized Movement Disorder Society–Unifi...

Association between candidate genes and FRAX scores in postmenopausal women

Abstract Purpose Single nucleotide polymorphisms (SNPs) have been associated with BMD and bone fracture risk. The aim of this study was to assess the possible association between FRAX scores and specific SNPs in Italian osteopenic and osteoporotic postmenopausal women. Methods We...

Double functionalization in chitosan scaffolds for bone tissue engineering improvement

Abstract Chitosan is a natural polysaccharide produced by the deacetylation of chitin. It has been employed for several biomedical applications since it is biocompatible and biodegradable. In this work, two synthetic peptides were covalently grafted to chitosan to enhance cellula...

Pricing semi-cooperation in unstable linear–linear bilevel programs via strictly convex tie-breaking and stability contracts

Abstract When the follower problem in a bilevel program admits multiple optimal solutions, the leader’s outcome depends on how ties are resolved. This yields the classical optimistic/pessimistic ambiguity and makes the model unstable (ill-posed) from a predictive viewpoint. We st...

Stage-dependent performance and molecular subtype-specific relapse patterns on same-session [18F]FDG PET/contrast-enhanced CT in breast cancer

PURPOSE: To evaluate stage-dependent performance of same-session [18F]FDG PET/contrast-enhanced CT (PET/ceCT) for initial breast cancer staging and PET/ceCT-detected relapse patterns during follow-up. METHODS: This retrospective single-centre study included a primary staging coho...

Tunable Oxygen Connectivity in Carbaporphyrinoid Polymers on Metal Surfaces

ABSTRACT Controlling oxygen‐mediated connectivity at metal surfaces offers a powerful route to engineer covalent and metal–organic architectures with atomic precision. Here, we demonstrate tunable oxygen‐based connectivity in carbaporphyrinoid polymers on Au(111) under ultrahigh...

Review of Particle Physics *

The Review summarizes much of particle physics and cosmology. Using data from previous editions, plus 3,200 new measurements from 903 papers, we list, evaluate, and average measured properties of gauge bosons and the recently discovered Higgs boson, leptons, quarks, mesons, and b...