University of Ottawa

The Effect of Ceratonia siliqua (Carob) on Male Infertility: A Systematic Review and Meta-analysis of invitro and randomized controlled trials.

Oxidative stress is a key contributor to impaired se-men quality in male infertility. Ceratonia siliqua L. (car-ob), a polyphenol-rich plant traditionally used to improve male fertility, has been investigated as a potential in-tervention for improving semen parameters and repro-d...

Periphery or Center? Ukrainian Modernism in Kyiv

Contesting the use of the geospatial concepts of “periphery” and “center,” this essay argues that a mathematical metaphor, the Möbius strip, better expresses the continuously morphing, interrelated, dynamic mesh that we call modernism. One of the major but still understudied node...

Evidence-based atlas of risk and protective factors for psychotic disorders: an umbrella review to inform personalized prognosis and prevention.

Identifying updated, evidence-based risk and protective factors for psychotic disorders is essential to advancing scientific and clinical knowledge of their etiology. Since the most recent umbrella review published in this journal, the evidence base has expanded substantially. Fo...

Nasal Packing After Trans-Sphenoidal Surgery for Pituitary Tumor: A Pilot of a Randomized Controlled Trial.

BACKGROUND AND OBJECTIVES: The goal of the study was to determine the feasibility of a larger trial to evaluate whether nasal packing after routine endoscopic endonasal resection of pituitary tumor negatively affects sinonasal quality of life (QOL) in the postoperative period and...

A screening template for knowledge synthesis: the IED-uOttawa algorithm

When conducting a knowledge synthesis, the screening of studies appears to be the critical task and is the most time-consuming segment and human resources. The development of the IED-uOttawa was the result of a hands-on natural experience using several knowledge synthesis project...

On the Inhibition of Lipid Peroxidation and Ferroptosis by Fatty Acids

Most inhibitors of lipid peroxidation (LPO) and associated ferroptosis are small molecules that trap LPO-propagating radicals. Among the handful of other inhibitors are select fatty acids: monounsaturated fatty acids (MUFAs) and polyunsaturated fatty acids substituted with deuter...

Development and evaluation of a quality assessment tool for equality, diversity, and inclusion (QUALITY-EDI) within healthcare research

Implementing equality, diversity, and inclusion (EDI) in healthcare research is critical to ensuring findings are translatable and provide the greatest benefit to patients who need it most. A quality assessment scoring tool (QUALITY-EDI) was developed to evaluate the conduct of E...

MRI Characteristics of Myelin Oligodendrocyte Glycoprotein Antibody-Associated Disease

Importance Myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD) is a demyelinating disease distinct from multiple sclerosis (MS) and aquaporin-4 antibody-positive neuromyelitis optica spectrum disorder (AQP4+NMOSD). Magnetic resonance imaging (MRI) is central t...

Rethinking Organisational Justice in Healthcare Through Nurses' Voices: Insights From Nancy Fraser's Theory of Justice

ABSTRACT Organisational justice has emerged as a key area of interest given the challenges of protecting the health and well‐being of nurses in healthcare organisations. Existing research shows significant conceptual and methodological limitations that must be addressed to achiev...

Machine learning–driven design of catalytic processes for sulfur dioxide oxidation: Lessons from the trenches

Abstract Despite the growing use of ML in chemical engineering, the catalytic conversion of sulfur dioxide (SO 2 ) to sulfur trioxide (SO 3 ) remains underexplored from a data‐driven modeling perspective. This study evaluates an integrated workflow for literature‐derived SO 2 oxi...

Hydro‐Mechanical Modelling of Gas Migration in Bentonite: Formulation and Laboratory‐Scale Validation

ABSTRACT Gas generation and migration in bentonite buffer materials are critical processes affecting the performance of deep geological repositories for radioactive waste. This study presents a new hydro‐mechanical formulation for simulating gas migration in saturated, compacted...

Clinical, biochemical and genetic spectra of carnosinemia: a systematic review of case reports and case series

Abstract Carnosinemia, also referred to as carnosinase 1 (CNDP1) deficiency, is an ultra-rare inborn error of metabolism characterized by impaired CNDP1 activity and carnosine degradation. The clinical significance and phenotypic spectrum of this condition remain poorly defined,...

P4-Days: Programmable Data-Plane Execution in a Multicore Discrete-Event Network Simulator

Packet-level simulation of P4-programmable networks is expensive because a software P4 pipeline must be interpreted for every packet at every programmable hop. Existing integration through P4sim provides realistic BMv2 execution inside ns-3, but ns-3 uses a sequential event core....

P4-Days: Programmable Data-Plane Execution in a Multicore Discrete-Event Network Simulator

Packet-level simulation of P4-programmable networks is expensive because a software P4 pipeline must be interpreted for every packet at every programmable hop. Existing integration through P4sim provides realistic BMv2 execution inside ns-3, but ns-3 uses a sequential event core....

The role of personality traits in arbitral decision-making

Purpose This study examines the relationship between arbitrators’ personality traits and three dimensions of arbitral decision-making: perceptions of decision bias, arbitral preferences, and preferred sources of decision-making. Design/methodology/approach A quantitative, deducti...

Clinical Improvement, No Improvement, and Worsening at 24 Hours Following Reperfusion in Patients With Stroke due to Large-Vessel Occlusion

BACKGROUND: Restoring blood flow to ischemic tissue is the cornerstone of acute stroke therapy and is usually beneficial. However, when reperfusion is achieved for severely injured tissue, it is often futile and may occasionally cause harm. We aim to determine the prevalence and...

The quantum spin Brauer category

We introduce a diagrammatic braided monoidal category, the quantum spin Brauer category , together with a full functor to the category of finite-dimensional type- 1 modules for U q ( 𝔰𝔬 ( N ) ) or U q ( 𝔬 ( N ) ) . This functor becomes essentially surjective after passing to the...

Protocol 1: Pediatric Rare Disease Clinical Trials Inventory: A Living Scoping Review Protocol

Scoping review protocol to develop an inventory of pediatric rare disease clinical trials, updated on an ongoing basis, to serve as a database to support research about the design, implementation, and evaluation of such trials.

Negotiating consent, sexualized substance use, and digital platforms among two-spirit, gay, bisexual, trans, and queer men: Perceptions of Canadian service providers

The interplay of digital platforms and sexualized substance use has reshaped Two-Spirit, gay, bisexual, trans, and queer (2SGBTQ) men’s sociality and wellbeing. 2SGBTQ men use digital platforms and sexualized substances at unprecedented rates. The overall aim of this research was...

Versatile Thin Polymer Fibers Produced by a Cotton-Candy Melt-Spinning Method: Examples of Dye Doping and Microplastic Generation

Abstract We report a method for producing thin plastic fibers (TPFs) in a few minutes using an inexpensive cotton-candy machine. Commercially available plastics (PP, PMMA, PETG, and PLA) were used to evaluate the versatility of this simple technique. Thin fibers are generated sta...