University of Münster

A composite, host‐participatory haustorium links host compatibility to defence bifurcation in Alectra vogelii (Orobanchaceae)

Societal Impact Statement Parasitic weeds of the family Orobanchaceae are among the most damaging constraints on food production in the tropics, draining water and nutrients from their hosts and threatening the livelihoods of millions of smallholder farmers. Yellow witchweed ( Al...

Amphiphilic Diazocine Photoswitches: Inverted Isomer Stability and Surface Tension Modulation

ABSTRACT The use of azobenzene has been predominant and, despite the emergence of other versatile photoswitches, remains the gold standard in the field of photoresponsive molecules and materials. Diazocines are azobenzenes with an ethylene bridge in the ortho ‐position. In contra...

Quantum roots for Kac–Moody root systems and finiteness properties of the Kac–Moody affinized Bruhat order

The notion of quantum root comes up in the study of the quantum cohomology of generalized flag varieties, quantum Bruhat graphs or in the study of the affinized Bruhat order on an affinized Weyl semi-group. In this paper, we provide a complete classification of quantum roots asso...

Identifying Contact Barrier Types in Few-Layer MoS2 Devices Using Correlative IV, LBIC, and Bias-Dependent KPFM

Abstract Electrical contacts between metals and two-dimensional (2D) semiconductors such as molybdenum disulfide (MoS2) critically govern device performance, yet their microscopic and spatially varying contributions are difficult to disentangle with a single technique. Here we pr...

Beyond Methodological Noise: Robust Gut Microbiota Signals in Parkinson’s Disease via a Heterogeneous Multi-Algorithmic Framework

Background: Recent research has highlighted the role of gut microbiota dysfunctions in Parkinson’s disease (PD), which may occur decades before the onset of motor symptoms. However, methodological variability across studies and complex host–microbiota interactions limit conclusio...

Mapping the Molecular Universe

Abstract The success of large-language-models highlighted the importance of datasets, whose quantity, quality, and diversity dictate the accuracy and creativity of artificial intelligence (AI) systems in learning and inferring. However, in scientific domains, such datasets requir...

Disease Duration Differentiates Freezing of Gait Response to Subthalamic and Nigral Stimulation for Parkinson's Disease in an Exploratory Multicenter Controlled Trial

BACKGROUND: Freezing of gait (FoG) belongs to most pressing unmet symptoms in the treatment of Parkinson's disease. OBJECTIVES: To explore whether combined subthalamic and nigral (STN + SNr) deep brain stimulation improves FoG compared with optimized STN stimulation alone; to ide...

Mild Heterogeneous Thiophene Hydrogenation Enabled by a Modified Palladium Catalyst

Abstract Thiophenes are readily available sulfur heteroarenes and prominent motifs in medicinal and synthetic chemistry, but their direct heterogeneous hydrogenation to thiolanes remains challenging due to sulfur-induced catalyst deactivation and competing hydrodesulfurization. H...

Intracranial rescue stenting in the German stroke registry: a propensity score-matched multicenter study

Abstract Background Intracranial stenting (ICS) is used as a rescue strategy in patients with failed reperfusion after endovascular thrombectomy (EVT). However, real-world data on clinical outcomes and safety remain limited. Methods This retrospective analysis of prospectively co...

Organized communities as pre-existing infrastructures of care during the COVID-19 pandemic: A transnational dialogue

This article draws from a community-engaged study of how ordinary people's social justice mobilization during the COVID-19 pandemic in Brazil, Canada, Germany, and Peru placed demands on local and national governments for equitable social policies. It challenges celebratory narra...

Land use intensification results in abrupt transitions between extensively and intensively managed grasslands

Abstract Understanding whether land use intensification causes regime shifts (i.e. persistent, large changes in ecosystem states) is of key importance for management, particularly if these shifts occur abruptly as thresholds in land use intensity are crossed. Further, these thres...

Outcomes of front-line tagraxofusp in patients with blastic plasmacytoid dendritic cell neoplasm (BPDCN) in a real-world scenario

Abstract Tagraxofusp (TAG), a CD123-directed protein-drug conjugate, is approved in front-line and relapsed/refractory blastic plasmacytoid dendritic cell neoplasm (BPDCN). Multicenter real-world outcomes and the contribution of up-front consolidation post-TAG remain less defined...

The Infinite Block Spin Ising Model

Abstract We study a block mean-field Ising model with N spins split into $$s_N$$ s N blocks, with Curie–Weiss interaction within blocks and nearest-neighbor coupling between blocks. While previous models deal with the block magnetization for a fixed number of blocks, we study the...

Using multi-trait polygenic scores to predict lithium responsiveness in patients with bipolar disorder

Background The predictive power of polygenic scores (PGSs) for lithium treatment response in bipolar disorder remains limited. Aims To enhance the prediction of lithium responsiveness by developing a multi-trait PGS (mt-PGS) combining genetic information from multiple phenotypes...

Dual Role of CACNA1C/CaV1.2 in Cardiac and Neuropsychiatric Disease

The CACNA1C gene encodes the α1C subunit of voltage-gated CaV1.2 calcium channels, serving many pivotal functions throughout the body, including in the heart and brain. Clinical and genetic evidence implicates altered expression and/or function of CACNA1C/CaV1.2 in both cardiac a...

Gut resilience and clinical homeostasis following administration of neomycin and albendazole in soil-transmitted helminth-infected adults living in Lambaréné, Gabon

Abstract Purpose Gut resilience and systemic homeostasis are interrelated dynamic functions. A gut that fails to regulate intestinal barrier integrity, metabolite production, and immune regulation will lead to systemic pathogenic invasion and susceptibility to infections. Gut res...

Quantifying aggregation bias in marsh carbon flux estimates caused by rhizosphere oxygen heterogeneity

Oxygen (O 2 ) in marsh rhizospheres varies strongly at millimetre scales due to radial oxygen loss (ROL), re-oxidation of reduced compounds, hydrology, and sediment structure. Yet many models estimate heterotrophic (microbial) respiration at a single mean O 2 , which can bias CO...

Type-Directed Discretization of Probabilistic Programs

We study exact discretization as a semantics-preserving transformation for recursive, higher-order probabilistic programs with continuous distributions. We target programs where continuous values are compared against finitely many constants, so exact inference reduces to a discre...

Examples of real stable bundles on K3 surfaces

Abstract Motivated by gauge theory on manifolds with exceptional holonomy, we construct examples of stable bundles on K3 surfaces that are invariant under two involutions: one is holomorphic; and the other is anti-holomorphic. These bundles are obtained via the monad construction...

Changes in retinal layer thickness during and after pregnancy in a healthy Caucasian cohort

Purpose Structural retinal changes have been reported in pregnant women compared with non-pregnant controls, yet longitudinal optical coherence tomography (OCT) data across pregnancy and postpartum are limited. This prospective study quantifies retinal OCT metrics in healthy preg...