University of Hong Kong

p38β-mediated BiP phosphorylation drives stemness and chemoresistance by suppressing UPR activation in hepatocellular carcinoma

Abstract Tumor-initiating cells (TICs) promote tumor initiation and therapy resistance, yet the kinase regulators that sustain TICs remain incompletely defined. Here, we identify the stress kinase p38β (MAPK11) supports TIC maintenance and drug resistance in hepatocellular carcin...

Durable Interphase Engineering on SiO x Anodes Through Interfacial‐Enrichment‐Facilitated Polymerization

ABSTRACT Constructing a robust solid electrolyte interphase (SEI) is a proven strategy to enhance the performance of Si‐based anodes by accommodating severe volume swings and suppressing interfacial side reactions. However, existing strategies that rely solely on either chemical...

Terminology for describing the 24-h cycle of physical activity, sedentary behaviour, and sleep: a scoping review

Abstract Background Physical activity, sedentary behaviour, and sleep are three behaviours which occupy the 24-h cycle and interact to influence a multitude of health outcomes. Different terms are currently used to describe these behaviours collectively (e.g., movement behaviours...

Photochemical Impactsfrom Resolving Isomers and InterferenceBiases in PTR-ToF-MS Measurements of Atmospheric VOCs

Abstract While proton-transfer-reaction time-of-flight mass spectrometry (PTR-ToF-MS) is widely used for ambient volatile organic compounds (VOCs) quantification, its accuracy is limited by isomeric speciation and ionization byproducts. Here, gas chromatography (GC) coupled with...

“It Can't be Translated Into a Conventional English Phrase” : Crafting Academic Identities Through Translingual Writing

ABSTRACT This qualitative multiple case study explores multilingual postgraduate students’ academic identities through writing at an EMI university in Hong Kong, with a focus on how they gain legitimacy in knowledge‑making with their multilingual repertoires. Grounded in a postst...

Achieving Synergistic Kinetics and Stability in Li‐Rich Mn‐Based Oxides via AlPO 4 ‐Assisted Multi‐Scale Regulation

ABSTRACT Realizing the full potential of Li‐rich Mn‐based oxides (LRMOs) is contingent upon overcoming the intrinsic conflict between sluggish anionic redox kinetics and structural instability. Conventional modification approaches often fail to harmonize kinetic enhancement with...

Homoepitaxial GaN-on-GaN trench MOSFETs with 438 MW/cm2 figure of merit and improved gate reliability

In this paper, we report enhanced high-voltage blocking capability and improved gate dielectric reliability in vertical GaN-on-GaN trench metal–oxide–semiconductor field-effect transistors (MOSFETs) through fabrication process optimization. A thick bottom dielectric (TBD) is intr...

Counterfactual load forecasting with LLM-structured events and representation learning

News-reported social, environmental, and grid events can substantially reshape electricity demand, yet quantifying how such events perturb forecasted load trajectories remains largely unaddressed. Existing news-augmented forecasting studies use news as auxiliary features to reduc...

Enhanced Ultrasound Transmission Through Aberration Layers Using Space‐Coiling Acoustic Metamaterials

Ultrasound is widely used in medical imaging and therapy. Yet its performance is limited by layers such as the skull or calcified tissue that exhibit an impedance mismatch with the background medium. As a result, wave energy scatters, phase distorts, and overall transmission decr...

Diagnosis and analysis of plasma phosphorylated tau 217 in a memory clinic cohort: limitations of Generative Pre-trained Transformer-5

INTRODUCTION: No published studies have evaluated the application of Generative Pre-trained Transformer-5 (GPT-5) in the analysis of memory clinic patient clinical notes or the interpretation of plasma phosphorylated tau (P-tau) 217 values. We compared Alzheimer's disease (AD) pr...

Beyond the 90 Reserved Days for Each Parent: Associations Between Fathers' Parental Leave Duration and Depression Symptoms in a Swedish National Cohort Study.

. 2026;116(8):1121-1129. https://doi.org/10.2105/AJPH.2026.308589).

Recent Advances in Interfacial Chemistry for Solid‐State Lithium–Sulfur Batteries

ABSTRACT All‐solid‐state Lithium–sulfur batteries (ASSLSBs) have emerged as a highly promising candidate for next‐generation energy storage systems, featuring a unique combination of earth‐abundant sulfur cathodes, high‐capacity lithium metal anodes, and nonflammable solid‐state...

Surface selection at the gripping interface for tensile testing per ASTM F2516 affects the pseudoelastic stress-strain response of Nitinol

Complications such as premature failure and sample slippage associated with testing uniform cross-sectioned samples using conventional gripping systems are well known within the testing community. While these complications can be avoided for most materials using dogbone-shaped sa...

Aligning Clinical Needs and AI Capabilities: A Survey on LLMs for Medical Reasoning

Abstract Large language models (LLMs) have emerged as important tools in healthcare, showing growing potential for clinical reasoning and patient care. This survey examines recent progress in medical LLMs, focusing on reasoning applications and requirements. We present a dual-vie...

Early life sugar rationing and ageing related diseases, biological ageing and mortality

Early-life nutrition may influence lifelong ageing, yet human evidence is scarce. Using Britain’s postwar sugar rationing as a natural experiment, we examine its long-term effects in 64,809 United Kingdom Biobank participants. Exposure to sugar rationing during the first 1,000 da...