University of Hong Kong

Developmental Relations Between Oppositional Defiant Disorder and Depression in Childhood: A Symptom Level Perspective

Background Oppositional defiant disorder (ODD) has substantial comorbidity with depression. However, their comorbidity at the symptom level, including potential gender differences, is currently underspecified. This study aimed to explore the comorbidity network of ODD and depress...

p38β-mediated BiP phosphorylation drives stemness and chemoresistance by suppressing UPR activation in hepatocellular carcinoma

Abstract Tumor-initiating cells (TICs) promote tumor initiation and therapy resistance, yet the kinase regulators that sustain TICs remain incompletely defined. Here, we identify the stress kinase p38β (MAPK11) supports TIC maintenance and drug resistance in hepatocellular carcin...

Terminology for describing the 24-h cycle of physical activity, sedentary behaviour, and sleep: a scoping review

Abstract Background Physical activity, sedentary behaviour, and sleep are three behaviours which occupy the 24-h cycle and interact to influence a multitude of health outcomes. Different terms are currently used to describe these behaviours collectively (e.g., movement behaviours...

Predicting infection risk in rheumatoid arthritis patients receiving biological or targeted synthetic disease-modifying anti-rheumatic drugs: an application of machine learning and healthcare big data

Patients with rheumatoid arthritis (RA) initiating biologic or targeted synthetic disease-modifying antirheumatic drugs (b/ts DMARDs) face elevated risk of serious infections, necessitating tools for individualized risk stratification. Primary objective was to develop and validat...

Photochemical Impactsfrom Resolving Isomers and InterferenceBiases in PTR-ToF-MS Measurements of Atmospheric VOCs

Abstract While proton-transfer-reaction time-of-flight mass spectrometry (PTR-ToF-MS) is widely used for ambient volatile organic compounds (VOCs) quantification, its accuracy is limited by isomeric speciation and ionization byproducts. Here, gas chromatography (GC) coupled with...

Achieving Synergistic Kinetics and Stability in Li‐Rich Mn‐Based Oxides via AlPO 4 ‐Assisted Multi‐Scale Regulation

ABSTRACT Realizing the full potential of Li‐rich Mn‐based oxides (LRMOs) is contingent upon overcoming the intrinsic conflict between sluggish anionic redox kinetics and structural instability. Conventional modification approaches often fail to harmonize kinetic enhancement with...

“It Can't be Translated Into a Conventional English Phrase” : Crafting Academic Identities Through Translingual Writing

ABSTRACT This qualitative multiple case study explores multilingual postgraduate students’ academic identities through writing at an EMI university in Hong Kong, with a focus on how they gain legitimacy in knowledge‑making with their multilingual repertoires. Grounded in a postst...

Homoepitaxial GaN-on-GaN trench MOSFETs with 438 MW/cm2 figure of merit and improved gate reliability

In this paper, we report enhanced high-voltage blocking capability and improved gate dielectric reliability in vertical GaN-on-GaN trench metal–oxide–semiconductor field-effect transistors (MOSFETs) through fabrication process optimization. A thick bottom dielectric (TBD) is intr...

Counterfactual load forecasting with LLM-structured events and representation learning

News-reported social, environmental, and grid events can substantially reshape electricity demand, yet quantifying how such events perturb forecasted load trajectories remains largely unaddressed. Existing news-augmented forecasting studies use news as auxiliary features to reduc...

Enhanced Ultrasound Transmission Through Aberration Layers Using Space‐Coiling Acoustic Metamaterials

Ultrasound is widely used in medical imaging and therapy. Yet its performance is limited by layers such as the skull or calcified tissue that exhibit an impedance mismatch with the background medium. As a result, wave energy scatters, phase distorts, and overall transmission decr...

Diagnosis and analysis of plasma phosphorylated tau 217 in a memory clinic cohort: limitations of Generative Pre-trained Transformer-5

INTRODUCTION: No published studies have evaluated the application of Generative Pre-trained Transformer-5 (GPT-5) in the analysis of memory clinic patient clinical notes or the interpretation of plasma phosphorylated tau (P-tau) 217 values. We compared Alzheimer's disease (AD) pr...

Surface selection at the gripping interface for tensile testing per ASTM F2516 affects the pseudoelastic stress-strain response of Nitinol

Complications such as premature failure and sample slippage associated with testing uniform cross-sectioned samples using conventional gripping systems are well known within the testing community. While these complications can be avoided for most materials using dogbone-shaped sa...

Recent Advances in Interfacial Chemistry for Solid‐State Lithium–Sulfur Batteries

ABSTRACT All‐solid‐state Lithium–sulfur batteries (ASSLSBs) have emerged as a highly promising candidate for next‐generation energy storage systems, featuring a unique combination of earth‐abundant sulfur cathodes, high‐capacity lithium metal anodes, and nonflammable solid‐state...

Beyond the 90 Reserved Days for Each Parent: Associations Between Fathers' Parental Leave Duration and Depression Symptoms in a Swedish National Cohort Study.

. 2026;116(8):1121-1129. https://doi.org/10.2105/AJPH.2026.308589).

Early life sugar rationing and ageing related diseases, biological ageing and mortality

Early-life nutrition may influence lifelong ageing, yet human evidence is scarce. Using Britain’s postwar sugar rationing as a natural experiment, we examine its long-term effects in 64,809 United Kingdom Biobank participants. Exposure to sugar rationing during the first 1,000 da...

Aligning Clinical Needs and AI Capabilities: A Survey on LLMs for Medical Reasoning

Abstract Large language models (LLMs) have emerged as important tools in healthcare, showing growing potential for clinical reasoning and patient care. This survey examines recent progress in medical LLMs, focusing on reasoning applications and requirements. We present a dual-vie...