University of Hong Kong

Comparative Efficacy Of Different Computer-Aided Detection Products in Colonoscopy: A Network Meta-Analysis Of Randomized Controlled Trials.

Background and aims: Multiple computer-aided detection (CADe) systems have been developed to improve adenoma detection during colonoscopy, but their comparative efficacy and consistency of effect remain uncertain. This network meta-analysis aimed to compare the efficacy of differ...

Beyond autonomy: cultural habitus and social scaffolding in elderly vaccination in post-pandemic Hong Kong

The COVID-19 pandemic reshaped vaccination behaviors, yet post-pandemic attitudes toward routine immunization among older adults remain underexplored in aging societies like Hong Kong. This study explores the impact and implications of the pandemic on influenza and pneumococcal v...

Reproducible left anterior-superior hypothalamic enlargement in episodic migraine: evidence from two independent cohorts

Growing evidence implicates the hypothalamus as a key structure in migraine pathophysiology; however, our understanding of its precise role and of the specific nuclei involved remains limited. We combined MRI data from our laboratory with publicly available MRI datasets from Open...

Exploring the hydrogen abstraction pathway in HOM formation from α -pinene photooxidation systems under varying NO conditions

Abstract. Highly oxygenated organic molecules (HOM) are formed via autoxidation during ⚫OH-initiated oxidation of α-pinene. We investigated the relative contributions of OH-addition and hydrogen (H)-abstraction to HOM formation from α-pinene photooxidation under varying nitrogen...

Experimental causal inference from measurements alone in the presence of spatial and temporal quantum correlations

The causal structure of a set of events specifies which events influence which others. Determining this structure, known as causal inference, is a fundamental task in science. Reset-style intervention is commonly used to determine causal structure in classical scenarios. However,...

Unravelling undergraduates’ development of evaluative judgments through AI-supported internal feedback

Making evaluative judgments is a core lifelong learning capacity and the foundation of student feedback literacy. However, its development in second language (L2) writing remains underexplored. This qualitative case study investigated how 28 undergraduates developed evaluative ju...

Living Structure + AI: A New Episteme for Liberal Arts and Whole-Person Education in the Era of Artificial Intelligence

The rapid integration of artificial intelligence (AI) into higher education marks a radical epistemic shift, unsettling long-held assumptions about how knowledge is made, taught, and judged. This paper argues that the theory of living structure offers a timely foundation for libe...

Cost utility analysis of two BK polyomavirus screening strategies: quantitative polymerase chain reaction vs 2-stage approach

Screening for BK polyomavirus (BKPyV) with quantitative polymerase chain reaction (qPCR) or a 2-stage approach with urine cytology followed by qPCR are acceptable strategies. However, the magnitude of the health benefits and incremental cost of adopting these 2 screening strategi...

Healing Following Endoscopic Reconstruction of the Anterior Skull Base in Patients With Sinonasal Malignancies

ABSTRACT Background Healing dynamics after anterior skull base (ASB) reconstruction following transnasal endoscopic surgery (TES) for sinonasal malignancies remain poorly characterized. This study aimed to describe the postoperative healing process, quantify time to healing, iden...

Trions as Fundamental Species in Chemically Doped Polymer Semiconductors

Doping is a cornerstone strategy for enhancing charge transport in semiconducting polymers, important for their application in, for example, semi-transparent electrode materials, thermoelectric devices, and antistatic coatings. Both chemical and electrochemical doping have, for t...

Genetic Predisposition and Pharmacological Effects Shape the Divergent Effects of Type 2 Diabetes on Atherosclerosis

Abstract Type 2 diabetes mellitus (T2D) increases the risk of atherosclerotic diseases, including coronary artery disease (CAD), but decreases that for abdominal aortic aneurysm (AAA), forming an intriguing diabetes-atherosclerosis paradox. We investigate how genetic underpinning...

Reconstructing Solvation Structure via Strongly Nucleophilic Anions for High‐Rate and Low‐Temperature Graphite||LFP Pouch Cells in PC‐Based Electrolyte

ABSTRACT Regulating Li + solvation structure in Propylene carbonate (PC)‐based electrolytes modulates solid‐electrolyte interphase (SEI) formation and desolvation, enabling compatibility with graphite anodes. However, existing high‐ and localized high‐concentration strategies rem...

Age-Associated Patterns of Cardiovascular Risk and Disease Phenotypes Across Diverse Care Settings: The GLOB-cAGE Consortium

Reported prevalence of cardiovascular disease (CVD) risk factors and phenotypes varies widely. In multi-cohort analyses, such variation reflects population risk, care setting, and data capture. We harmonized baseline data from four analytic cohorts (N=54,188, aged ≥50 years) in f...

Allosterically Controlled Capture of Mutually Repulsive Guests With Positive Cooperativity and Ultrahigh Affinity

ABSTRACT A hexacationic cage incorporating three urea units can encapsulate two mutually repulsive anions in close proximity through a combination of hydrogen bonding and electrostatic interactions. This leads to exceptionally high binding affinities, with a K 1 × K 2 value of ap...

Phenomic Medicine and Metabolic Disease Trajectories: Measuring and Modelling the Health to Disease Continuum

Abstract Phenomic medicine is an emerging field that involves measurement and modelling of multidimensional phenotypic data to provide a systems-level framework to understand how health and disease evolve over time and inform decision making in a clinical context . Unlike genomic...

A Configurable and Highly Efficient NTT/INTT/PWM Unit for CRYSTALS-Kyber and CRYSTALS-Dilithium

CRYSTALS-Kyber and CRYSTALS-Dilithium are representative lattice-based post-quantum cryptographic schemes, where number theoretic transform (NTT), inverse NTT (INTT), and point-wise multiplication (PWM) dominate polynomial arithmetic. Existing hardware accelerators are typically...

Intensity-StableWavelength Tuning in InGaN/GaN MultipleQuantum Wells

Abstract Dynamic tuning of emission from III-nitride multiple quantum wells (MQWs) without significant intensity variation is a highly desirable feature as the emission wavelength from MQWs is generally fixed. This work demonstrates a three-terminal InGaN/GaN field-effect light-e...

Virtual Health Interventions to Improve Breastfeeding: A Systematic Review

CONTEXT Use of virtual health interventions has increased rapidly, with growing evidence evaluating virtual breastfeeding support. However, the effectiveness of different types of virtual breastfeeding interventions remains unclear. OBJECTIVE To examine the effects of various typ...

Developmental Relations Between Oppositional Defiant Disorder and Depression in Childhood: A Symptom Level Perspective

Background Oppositional defiant disorder (ODD) has substantial comorbidity with depression. However, their comorbidity at the symptom level, including potential gender differences, is currently underspecified. This study aimed to explore the comorbidity network of ODD and depress...

Predicting infection risk in rheumatoid arthritis patients receiving biological or targeted synthetic disease-modifying anti-rheumatic drugs: an application of machine learning and healthcare big data

Patients with rheumatoid arthritis (RA) initiating biologic or targeted synthetic disease-modifying antirheumatic drugs (b/ts DMARDs) face elevated risk of serious infections, necessitating tools for individualized risk stratification. Primary objective was to develop and validat...